1. Cell Membrane and Transport On the left side of your IntNB, draw the set-up of the demonstration once it has been explained to you. Make an hypothesis as to which direction the liquid will flow.

2. The plasma/cell membrane is selectively permeable ~only certain substances are allowed to pass through

3. What can and can not pass through the membrane? CAN PASS THROUGH Things that can dissolve in fat Small molecules Water CAN NOT PASS THROUGH 1.Things that can dissolve in water 2.Large molecules 3.Ions: Molecules with plus (+) or minus (-) charges CH 2 OH OH

4. What is an Isotonic Solution? [Water] inside cell = [Water] outside cell Cell is at equilibrium –Molecules are equally distributed in end The amount of water entering the cell = the amount of water leaving the cell 95% water

5. What is a hypotonic solution? A solution that has MORE water, and LESS solute The cell can lyse or burst if left in a hypotonic solution 100% water 95% water

6. What is a hypertonic solution? A solution that has LESS water and MORE solute The cell will dehydrate 90% water 95% water

7. What can pass through a membrane? (p. 253) Can pass through membrane Cannot pass through membrane Solubility? Size? Charge? Water soluble Fat soluble Small Large Uncharged Molecules Ions (H+, Na+, HCO3-, K+…)

8. The Plasma Membrane (p. 251) TEM of a red blood cell Hydrophilic Region Hydrophobic Region Phospholipid Proteins Carbohydrate side chains Glycoprotein Inside of Cell Outside of Cell

9. No energy is used [High]  [Low] (it’s the natural flow) This means it goes down a concentration gradient There are three types…

10. [High]  [Low] Passive Transport: Diffusion

11. Osmosis Passive Transport: Osmosis (Diffusion of water)

12. Facilitated Diffusion + CH 2 OH OH Passive Transport: Facilitated Diffusion

13. Energy is used [Low]  [High] This means it goes up or against a concentration gradient There are three types…

14. Protein Pumps store Protein Pumps: proteins use energy to pull or pump materials into or out of the cell to stockpile or store substances the cell needs Active Transport: Protein Pumps

15. Different Types of Membrane Proteins (page 252) TRANSPORTERSRECEPTORSENZYMES SIGNAL/ RECOGNITION

16. Different Types of Membrane Proteins (page 252) signal/recognition Enzymes receptor transporter

17. Endocytosis When cells engulf particles into the cell 2 types 1.Phagocytosis: When a cell wraps part of its membrane around a large particle forming a “pocket” or vesicle 2.Pinocytosis: The same process, but with smaller particles or liquids Active Transport: Endocytosis

18. Exocytosis 1.A vesicle carrying a substance 2.fuses with the cell membrane 3.and releases the substance Active Transport: Exocytosis