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www. Decaturfamilypsychiatry.com
160 Clairemont Ave Ste 445 Decatur, GA 30030 www. Decaturfamilypsychiatry.com
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Just In: Aspergers Prevalence Predicted To Fall To Zero
PHARMA & HEALTHCARE 12/04/2012
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Classic Autism A child labeled today as having an Autism Spectrum Disorder may look very different from the child diagnosed 30 years ago with Autism. At that time we diagnosed children who more closely resembled the children first described by Dr. Leo Kanner, in the seminal paper, Kanner, L. (1943), Autistic Disturbances of Affective Contact, Nervous Child 2, pp
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Types of Autism Spectrum Disorders/ Pervasive Developmental Disorders
Autistic Disorder Asperger’s Disorder Rett’s Disorder Childhood Disintegrative Disorder Pervasive Developmental Disorder- Not otherwise specified
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Asperger’s Disorder Impairments in social interaction
Problems with nonverbal social interactions such as eye gaze, facial expression, gestures and/or body posture Problems with peer relationships and an inability to form peer relationships appropriate to his/her age Problems with shared pleasure or enjoyment and a failure to seek such interaction with other people. (For example not pointing out interesting objects or not bringing a toy or object to an adult to share in the interest.) Problems with normal give-and-take of social interactions like taking turns or expressing emotions when socially appropriate
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Autism Spectrum Disorders
Persistent deficits Social communication/ interaction Restricted, repetitive pattern of behavior, interests, activities Present, early developmental period; may manifest later Impairment, assess each deficit separately Severity (each deficit) Requiring support, requiring substantial support, requiring very substantial support Specifiers With/ without accompanying intellectual impairment With/ without accompanying language impairment Associated with known medical or genetic condition or environmental factor Associated with another neurodevelopmental, mental, or behavioral disorder With catatonia
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Communication Disorders
Social (Pragmatic) Communication Disorder Persistent difficulties – social use of verbal & nonverbal communication Social Change with context/ listener Rules of conversation/ story-telling Non explicit Functional limitations Onset, early developmental period
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Changes Consolidation of all variants into 1 disorder Specifiers to indicate specific characteristics
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J Am Acad Child Adolesc Psychiatry. 2012 Apr;51(4):368-83. doi: 10
J Am Acad Child Adolesc Psychiatry. 2012 Apr;51(4): doi: /j.jaac Epub 2012 Mar 14. Sensitivity and specificity of proposed DSM-5 diagnostic criteria for autism spectrum disorder. McPartland JC, Reichow B, Volkmar FR.
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Asperger - 1944 “Autistic Psychopathy” Series of cases – all male
Marked social problems Good cognitive/language skills Motor problems Circumscribed interests Positive family hx (esp. fathers)
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Asperger: 1944 Unusual circumscribed interests
- all absorbing, interfered with functioning - family life would revolve around these Motor Skills - Often clumsy - poor body awareness
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Asperger: 1944 Social Disability Communication Problems
couldn’t join groups lack of friends even though interested in others intellectualization of affect conduct problems (noncompliant/negativistic) Communication Problems verbosity, one sided style impaired nonverbal skills idiosyncratic communication “little professors”
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Asperger Syndrome Limited Interest until early 1980’s
Limited Interest until early 1980’s - Van Krevelen in 1970’s – emphasized personality trait Wing (1981) synthesis and case series modifications in Asperger’s description some features - mild MR possible language problems possible continuity with autism case reports
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Asperger’s 1981 - 1994 Lack of consistent criteria
- markedly different views of the syndrome developed Issue of risk psychosis/violence Comparisons to Autism
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Other Diagnostic Constructs
From Neuropsychology - Nonverbal Learning Disabilities (NLD) From Neurology - Right Hemisphere Syndromes - Developmental Disabilities of the Right Hemisphere From Psycholinguistics - Semantic-Pragmatic Disorder Also - “Hyperplexia”, Schizoid Personality in Childhood, OC Behaviors, . . .
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Asperger’s Syndrome Inconsistencies in Use
Issues with lack of consensual criteria AS = higher functioning autism (without MR) AS = adults with autism AS = PDD-NOS/ “mild autism” AS = shyness/ “nerds” (shades into normalcy) AS = complex profiles associated with social problems AS = distinctive disorder
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Autism Spectrum Disorders
Persistent deficits Social communication/ interaction Restricted, repetitive pattern of behavior, interests, activities Present, early developmental period; may manifest later Impairment, assess each deficit separately Severity (each deficit) Requiring support, requiring substantial support, requiring very substantial support Specifiers With/ without accompanying intellectual impairment With/ without accompanying language impairment Associated with known medical or genetic condition or environmental factor Associated with another neurodevelopmental, mental, or behavioral disorder With catatonia
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Communication Disorders
Social (Pragmatic) Communication Disorder Persistent difficulties – social use of verbal & nonverbal communication Social Change with context/ listener Rules of conversation/ story-telling Non explicit Functional limitations Onset, early developmental period
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A particularly common problem in adolescents/adults
Depression A particularly common problem in adolescents/adults Growing awareness may risk for depression ? Genetic vulnerability Drug Treatments - Importance of careful diagnosis (difficulties in dx) - Track changes over time in mood and symptoms - Agents: SRIs, tricycle antidepressants - Need for appropriate monitoring, keep in mind time course and potential side effects
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Anxiety Various agents available Risk for anxiety problems
- Origins unclear - social limitations? Intrinsic? - Frequent victimization, difficulties in dealing with transitions, lack of empathy yet sufficient ability to realize that they are not “ getting it” Various agents available - SSRIs -minor tranquilizers, buspirone - alpha-adrenergic agonist medications - issues of disinhibition
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Anxiety Risk for anxiety problems
- Origins unclear - social limitations? Intrinsic? - Frequent victimization, difficulties in dealing with transitions, lack of empathy yet sufficient ability to realize that they are not “ getting it” Various agents available - SSRIs -minor tranquilizers, buspirone - alpha-adrenergic agonist medications - issues of disinhibition
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Don’t loose sight of the big picture
Goals for Education Academic Curriculum Don’t loose sight of the big picture Long-term goals - each item evaluated in terms of benefits for socialization, vocational potential, and quality of life - avoid curriculum inflexibility (i.e. strict adherence to credit system) - curriculum modification: the concept of “secondary gains” Emphasis on strengths that may serve vocational goals Mentorship, specific projects Foster motivation, self-initiative, and positive self-concept
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