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Abdominal Pain: Hot or Not
Abdulwahab Telmesani MD College of Medicine Umm Al-Qura University
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Abdominal Pain: Hot or Not!
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Abdominal Pain Acute Chronic
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Acute Abdominal Pain 5% of the unscheduled visits to clinics
Sense of urgency Gets proper attention
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Chronic Abdominal Pain
Pathological (Organic abdominal pain). Functional abdominal pain (Non organic)
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Chronic Abdominal Pain (Non organic/Functional)?
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Chronic Abdominal Pain (Non organic/Functional)
No objective evidence of an Underlying organic disorder.
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Chronic Abdominal Pain (Pathological)?
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Chronic Abdominal Pain (Pathological)?
Alarm symptoms or signs RED FLGS
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Chronic Abdominal Pain Pathological
Weight loss.
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Chronic Abdominal Pain Pathological
Weight loss. Gastrointestinal bleeding.
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Chronic Abdominal Pain Pathological
Weight loss. Gastrointestinal bleeding. Persistent fever.
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Chronic Abdominal Pain Pathological
Weight loss. Gastrointestinal bleeding. Persistent fever. Chronic severe diarrhea.
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Chronic Abdominal Pain Pathological
Weight loss. Gastrointestinal bleeding. Persistent fever. Chronic severe diarrhea. Significant vomiting.
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Chronic / Functional Abdominal Pain
Why?
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Chronic / Functional Abdominal Pain
A common problem Indication of higher prevalence in our society It is a cry for help
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Chronic / Functional Abdominal Pain Terms Used
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Chronic / Abdominal Pain Terms Used
Chronic recurrent abdominal pain RAP Functional abdominal pain Nonorganic abdominal pain Psychogenic abdominal pain Rome II criteria for abdominal pain
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Chronic recurrent abdominal pain (RAP)
3 episodes of abdominal pain, over a period of 3 mo, severe enough to affect activities
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Functional abdominal pain
Abdominal pain that occurs in the absence of anatomic abnormality, inflammation, or tissue damage
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Functional abdominal pain
Used interchangeably with: Nonorganic abdominal pain & Psychogenic abdominal pain
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Rome II criteria for abdominal pain?
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Rome II criteria for abdominal pain
In 1999, a group of investigators (Rome II committee) was charged with identifying and then developing diagnostic criteria for childhood functional disorders including recurrent abdominal pain.
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Rome II criteria for abdominal pain
Functional dyspepsia. Irritable Bowel Syndrome (IBS). Functional abdominal pain. Abdominal migraine.
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Rome II criteria for abdominal pain
Functional dyspepsia. Upper abdominal pain, recurrent or persistent x 12 wks. Non organic.
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Rome II criteria for abdominal pain
Functional dyspepsia. Upper abdominal pain, recurrent or persistent x 12 wks. Non organic. Irritable Bowel Syndrome (IBS). Abdominal discomfort x 12wks + changed stool frequency and form.
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Rome II criteria for abdominal pain
Functional dyspepsia. Upper abdominal pain, recurrent or persistent x 12 wks. Non organic. Irritable Bowel Syndrome (IBS). Abdominal discomfort x 12wks + changed stool frequency and form. Functional abdominal pain. Abdominal pain more than 12 wks in a school-aged child or adolescent.
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Rome II criteria for abdominal pain
Functional dyspepsia. Upper abdominal pain, recurrent or persistent x 12 wks. Non organic. Irritable Bowel Syndrome (IBS). Abdominal discomfort x 12wks + changed stool frequency and form. Functional abdominal pain. Abdominal pain more than 12 wks in a school-aged child or adolescent. Abdominal migraine In the preceding 12 mo three or more paroxysmal episodes of intense, acute midline, abdominal pain lasting 2 h to several days, with intervening symptom-free intervals lasting weeks to months. (2 of; headache, one side, photophobia FHx, Aura)
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Epidemiology
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13% of middle-school students and 17%
of high-school students experience weekly abdominal pain. Hyams JS et al J Pediatr. 1996
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Functional Abdominal Pain
Up to 15% of the school age children. Youssef NN. Clinical Pediatrics 2007
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IN KSA
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27/55(26.2%) middle school students.
RAP was found in 55/314 (17.5%). 27/55(26.2%) middle school students. 28/55(13.3%) secondary school students. Telmesani A (unpublished)
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Associated complaints/symptoms
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Associated complaints/symptoms
Headache, Joint pain, Anorexia, Vomiting, Nausea, Excessive gas, and altered bowel symptoms.
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Our bowl is a mirror for our emotions !
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The pain is real. The child is not faking
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RAP & Anxiety children meeting criteria for RAP endorsed
significantly greater trait anxiety, anxiety sensitivity, pain anxiety, and somatic symptoms as compared to those not meeting RAP criteria Drews, Amanda. Dissertation 2006
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The impact of recurrent abdominal pain: predictors of outcome in a large population cohort.
Children with recurrent abdominal pain are at significant and continuing risk of adverse functioning. Ramchandani, Paul G. et al Acta Paediatrica
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School stressors, psychological complaints and psychosomatic pain.
School stressors are strongly associated with psychosomatic pain and psychological complaints in school children. Hjern A. et al Acta Paediatrica
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Recurrent abdominal pain, anxiety, and depression in primary care.
Anxiety disorders were significantly more likely to precede RAP. Ramchandani, Paul Child: Care, Health & Development 2004
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The significance of life-events as contributing factors in childhood RAP
This study strongly suggests that recent stressful life-events are important risk-factors for RAP. Boey CC ; Goh KL J Psychosom Res. 2001
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IN KSA
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Relation of Anxiety and Depression with Psychosomatic Symptoms in children at a Primary Health Care center at Makkah Al-Mukarama 2003 Halah S. Dahlan (MOH)
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Results The relation of Anxiety and Psychosomatic Symptoms (RAP) represents 53% of the cases. The relation of Depression and Psychosomatic Symptoms (RAP) represents 57% of the cases.
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Conclusion RAP is the most common indicator of psychological problems which can be detected and handled at early stages.
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RAP and H. pylori?
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RAP and H. pylori A causal relationship between H. pylori infection and recurrent abdominal pain of childhood is still not proven.
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RAP and H. pylori A population-based cross-sectional study among
1221 preschool children aged 5–8 years. A clear association between recurrent abdominal pain with social and familial factors, but not with H. pylori infection Bode G et al J Psychosom Res 2003
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RAP and H. pylori In 65 H. pylori positive children (age: 3–12 years) with recurrent abdominal pain, 83% of the children had complete symptomatic relief after eradication therapy Das BK Et al J Trop Pediatr 2003
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IN KSA
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27/55(26.2%) middle school students.
RAP was found in 55/314 (17.5%). 27/55(26.2%) middle school students. 28/55(13.3%) secondary school students. Telmesani A (unpublished)
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Students with RAP and H. pylori positive, 35/55
(63.6%), compared to 55/314 (27%) overall. Telmesani A (unpublished)
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Investigation
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Investigation A technical review found little or no evidence to
suggest that ultrasonography, endoscopy, or esophageal pH monitoring increase the yield of organic disease in the absence of alarm-symptoms. The 2005 AAP and NASPGHAN guidelines
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Investigation Rarely limited noninvasive investigations
can be done to reassure very anxious parents. The 2005 AAP and NASPGHAN guidelines
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Treatment
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Treatment The primary goal is return to normal function
AAP and NASPGHAN 2005
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Treatment Counseling (Psychologist help) Psychological support
Reverse the Physical and Psychological stress factors Remove augmentation (lactose intolerance)
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Treatment Parents insight and reassurance of no pathology
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Treatment Cognitive-behavioral therapy may be useful in improving pain and disability in the short-term AAP and NASPGHAN 2005
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Treatment Evidence regarding the benefit of treatment
with H2 receptor agonists, supplemental fiber, or a lactose-free diet is inconclusive. AAP and NASPGHAN 2005
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A Randomized Double-Blind Placebo-Controlled Trial of Lactobacillus GG for Abdominal Pain Disorders in Children. The LGG appears to moderately increase treatment success, particularly among children with IBS. A. GawroŃska et al Aliment Pharmacol Ther. 2007
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Probiotics and Abdominal Pain.
Modulation of pain perception. Some Lactobacillus strains appear to induce expression of micro-opioid and cannabinoid receptors in intestinal epithelial cells and mediate analgesic functions in the gut in a manner similar to the effects of Morphine. Rousseaux, C et al Nat Med 2007
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Hot or Not?
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It’s Hot
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Conclusions RAP is a common problem It is a real pain
Requires no or limited investigations Pay attention to red flags Parental engagement and reassurance Remove psychological stressors.
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