1. Life Science Genetics

2. Genetics The study of heredity, how traits are passed from parent to offspring x = or

3. The study of heredity started with the work of Gregor Mendel and his pea plant garden Mendel was an Austrian Priest that lived in the mid 1800’s

4. Mendel noted that the size of pea plants varied. He cross-bred these pea plants to find some surprising results.

5. Mendel’s cross between tall pea plants yielded all tall pea plants. His cross between small pea plants yielded all small pea plants. Mendels’ cross between tall pea plants and small pea plants yielded all tall pea plants. X = x = X =

6. Mendel then crossed these second generation tall pea plants and ended up with 1 out 4 being small. x =

7. Mendel’s work led him to the understanding that traits such as plant height are carried in pairs. -Carrying the information are chromosomes. -Chromosomes are made up of sections called genes. -Genes are made up of DNA

9. DNA D.N.A. - Deoxyribonucleic Acid Molecule made of: 1. Deoxy Sugar 2. Combination of four nitrogen bases Either:a. Guanine b. Cytocine c. Thymine d. Adenine The sum total of combinations that these four bases are capable of creating are greater than all the stars visible in the night time sky

10. DNA Nitrogen bases pair up – Cytosine & Guanine – Thymine & Adenine Pairing creates a ladder shape Angle of bonds creates a twist Ladder and Twist produces the famous “Double Helix”

11. DNA DNA resides in all cells – Inside the nucleus Each strand forms a chromosome Cell Nucleus DNA

12. DNA is found in all living cells – It controls all functions inside a cell – It stores all the genetic information for an entire living organism – Single cell like an amoeba – Multi cell like a human

13. Genetics Small sections of DNA are responsible for a “trait”. These small sections are called “Genes”. – Gene - A segment of DNA that codes for a specific trait – Trait - A characteristic an organism can pass on to it’s offspring through DNA Gene

14. Genetics Skin color is a perfect example of an incomplete trait Bart has yellow skin Smurfette has blue skin What color skin should their children have?

15. Genetics There are four basic kinds of genes: – Dominant - A gene that is always expressed and hides others – Recessive - A gene that is only expressed when a dominant gene isn’t present – Codominant – A form of inheritance in which both alleles are equally shown. – Incomplete Dominant- Genes that work together to produce a third trait

16. Genetics Punnet Square - A tool we use for predicting the traits of an offspring – Letters are used as symbols to designate genes – Capital letters are used for dominant genes – Lower case letters are used for recessive genes – Genes always exist in pairs

17. Genetics A Widows Peak, dominant, would be symbolized with a capital “W”, while no widows peak, recessive, would be symbolized with a lower case “w”. Father - No Widows Peak - w Mother - Has a Widows Peak - W

18. Genetics All organisms have two copies of each gene, one contributed by the father, the other contributed by the mother. Gene Types: Homo - Same Hetero - Opposite Pheno – Physical Geno - Genetic

19. Genetics We can use a “Punnet Square” to determine what pairs of genes Lilly has Wwww Wwww w w Ww Assume Lilly is heterozygous Ww Assume Herman is homoozygous recessive ww A Punnet Square begins with a box 2 x 2 One gene is called an “allele” One parents pair is split into alleles on top, the other along the side Each allele is crossed with the other allele to predict the traits of the offspring

20. Genetics Another possibility is that Lilly might be “WW”, homozygous dominant. Ww w w WW Assume Lilly is homozygous dominant WW Assume Herman is homoozygous ww Ww Notice that all the offspring are heterozygous and will have a widows peak

21. Genetics All the offspring from Bart and Smurfette will be heterozygous, “YB”, and since skin color is incomplete dominant….. all their children will have green skin (or a blend). Incomplete dominance - A form of inheritance in which the heterozygous alleles are both expressed, resulting in a combined phenotype +

22. Genetics The flowers in the picture below show codominance. Because one parent flower is white and the other is pink, the offspring will be pink and white. Codominance - A form of inheritance in which both alleles are equally shown. +

23. Cell Division (Meiosis) 1. A process of cell division where the number of chromasomes is cut in half 2. Occurs in gonads (testes, ovaries, stamens, etc) 3. Makes gametes (sperm, ova, pollen, etc)