1. Tips for writing well and getting your work published Madhukar Pai, MD, PhD McGill University, Montreal Editorial board member: Lancet Infect Dis PLoS Medicine PLoS One International J of TB and Lung Disease Journal of Epidemiology & Global Health

2. In academia, publications are critical for success (tenure, grants, etc.)

3. To get postdoctoral or advanced training positions, publications are quite critical

4. Publishing is the natural culmination of your hard work. Be a finisher! Do not contribute to the already bad problem of publication bias!!

5. While almost all trials with “positive” results on antidepressants had been published, trials with “negative” results submitted to the US Food and Drug Administration, with few exceptions, remained either unpublished or were published with the results presented so that they would appear “positive”

6. BMJ 2012

7. Optimism bias, non-replicated studies, and selective reporting

8. If exposure and disease are not associated False positive study 100 studies will be designed If  = 0.05 5 studies show false positive results 5 studies will be published Publication Bias Positive results bias Editor’s bias THE FALSE POSITIVE RESEARCH CYCLE (Choi, 1998) Courtesy: Bernard Choi, PHAC Likely to be meta-analyzed Hot topic Bias

9. PLoS Med 2005

10. Here are some

11. Target the right journal Tell a clear, simple story [identify your message early] Follow a clear structure [why you started, what you did, what you found, and what it means]

12. You know a lot about your research; do not assume the editors and reviewers do!

13. Have others read your manuscript before submission – A good guide will give critical but constructive feedback – You could present your paper to a group and get great feedback Go through multiple drafts before submitting Make sure your final manuscript is polished and presentable (no typos, no bad formatting, etc.) Be very careful about copying and pasting from online sources (plagiarism)

15. Follow existing standards/templates (STARD, CONSORT, PRISMA, STROBE, etc.) – use subheads liberally Do not overstate the importance of the findings Clearly discuss study limitations Do not expect the paper to get accepted: – Revise and resubmit is the most desirable first decision! If asked to revise, address every comment and do it politely – Make it easy for the editor to see that you have addressed all comments thoroughly – You don’t have to make all changes, but you need to explain what you did and why

16. Peer reviews can greatly improve your paper – Take reviews seriously and learn from them

17. If rejected (which will happen a lot!), use the reviews to improve the paper and quickly re-submit – perseverance is critical for success

18. I began my journey 15 years ago…

19. And have persisted, and gotten better (hopefully!)

20. As with everything else, you get better at writing/publishing with time!