1. 1 DISCONTOOLS Update CWG Meeting, Rome, 30 th January 2015 Johannes Charlier, DISCONTOOLS Project Manager

2. 2 Content Summary of activities in 2014 –Update progress 12 prioritised diseases –Communications –Website –Funding Activities planned in 2015

3. 3 About DISCONTOOLS –Objective: Develop and maintain a database containing critical information relevant to research needs in terms of knowledge gaps in relation to diagnostics, vaccines and pharmaceuticals. –Output is Public website containing disease information for 52 infectious diseases with gap analysis and prioritisation model. –Contributes to consensus across stakeholders concerning gaps and priorities to spend scarce research resources

4. 4 12 diseases in focus (1) Existing - AI, ASF, BTB, Campylobacter, Cysticercosis, E. coli, FMD, Nematodes, ParaTB, PRRS, SIV New – PEDV List determined by funders with offer to work on Cysticercosis & PEDV

5. 5 Expert group leaders DiseaseExpert group leader appointed AITimm Harder ASFJosé Sanchez-Vizcaino BTMargarida Correia Neves CampylobacterElina Lahti and Ingrid Hansson CysticercosisPierre Dorny E.coliRoberto La Ragione FMDDavid Paton NematodesJozef Vercruysse ParaTBHerman Barkema PEDVHans Nauwynck PRRSHans Nauwynck SIVKristien Van Reeth

6. 6 We developed online scoring system for gap analysis and prioritisation model Supports expert group leaders in collecting the information www.soscisurvey.de /DISCONTOOLS

7. 7 Progress for the 12 diseases (1) DiseaseEG leader agreed to do the work EG established Final documents when? ASFyes Finished ParaTByes Expected February Nematodesyes Expected February FMDyes Expected February E. coliyes Expected February-March BTByes Applied for funding FORMAS Campylobacteryes Considering to apply for funding FORMAS (March 2015) AIyes Expected 2015

8. 8 Progress for the 12 diseases (2) DiseaseEG leader agreed to do the work EG established Final documents when? CysticercosisyesExpected 2015 SIVyesExpected 2015 PRRSVyesExpected 2015 PEDVYesExpected 2015

9. 9 Communication materials Poster was developed which can be used to present DISCONTOOLS activities at several occasions Leaflet was developed explaining the current work of DISCONTOOLS (will be sent upon request) Scientific paper was not accepted by Prev. Vet. Med., now being considered for submission to Scientific and Technical Review of OIE

10. 10 Conferences DISCONTOOLS was presented at –CYSTINET conference (4-5 Sep 2014, Antwerp), presentation –PROVAXS seminar “Innovation in animal health through academia-industry partnerships” (4 th Nov 2014, Ghent), poster Next planned conferences –SVEPM conference (March, Ghent), poster –WAAVP conference (August, Liverpool), poster

11. 11 Website (1) User statistics: –> 6000 visitors in 2014 (± 500 / month). –worldwide coverage

12. 12 Website (2) We are investing to make the database easier to consult and include graphical display of prioritisation model.

13. 13 Funding (1) Countries having agreed to make a provision for 2015 Contributed in 2014Made Provision for 2015 AustriaYes GreeceYes Ireland ItalyYes SwitzerlandYes The NetherlandsYes UK – DEFRA UK - BBSRC (meetings) Sweden – FORMAS (meetings) New: Spain

14. 14 Funding (2) Last funders meeting: Alex Morrow to explore collaboration with OIE In addition, we are considering a COST application (Deadline 24 st March 2015) “Novel approaches for the prioritization of research on neglected and emerging diseases of animals”

15. 15 Work programme 2015 (1) Continue work with expert groups to update the D&Ps and scoring sheets Review and finalise the updated documents for approval by PMB and funders Organize PMB meeting Load the approved information on the website

16. 16 Work programme 2015 (2) Identify new diseases to initiate the updating procedure, liaising as much as possible with existing initiatives –Brucellosis (recent gap analysis performed, cfr. Alex Morrow) –Leishmaniasis? (New Marie-Curie Training Network) –Other ?

17. 17 Conclusions Significant progress has been made for the 12 prioritised diseases, although for some diseases progress is more slow than anticipated (EG leaders “overbooked”). Need to identify new diseases to initiate the reviewing process, by preference liaising with existing initiatives. More results to be presented on a next Funder’s meeting in September?

18. 18 For more information please consult: www.discontools.eu Rue Defacqz, 1 1000 Brussels, Belgium Tel.: +32 (0)2 543 7570 Fax: +32 (0)2 537 0049