1. AMBIENT AIR POLLUTION, FETAL GROWTH AND PREMATURE BIRTHS IN POLISH URBAN POPULATION Bogdan Wojtyniak Jakub Stokwiszewski Daniel Rabczenko National Institute of Hygiene, Warsaw

3. The purpose of the study was to examine if exposure to outdoor air pollution during pregnancy is associated with increased risk of adverse birth outcomes in Polish urban population Air pollutants Black smoke (BS) Sulphur dioxide (SO 2 ) Nitrogen dioxide (NO 2 ) Birth outcomes Low birth weight (<2500g) Prematurity (<37 weeks) Intrauterine growth retardation Birth weight

13. Birth outcomes by the variables included in the models

15. Dose response curves for association between mean birth weight and BS during 1st trimester of pregnancy

16. Dose response curves for association between risk of low birth weight and SO 2 and BS during 1st and 3rd trimester of pregnancy in Lodz

17. Dose response curves for association between risk of IUGR and SO 2 and BS during 1st and 3rd trimester of pregnancy in Lodz

18. Dose response curves for association between mean birth weight and SO 2 and BS during 1st and 3rd trimester of pregnancy in Lodz

19. Dose response curves for association between risk of premature birth and SO 2 during 1st trimester of pregnancy

20. Dose response curves for association between risk of premature birth and SO 2 during 3rd trimester of pregnancy

21. Risk of premature birth associated with 10mg/m3 increase in ambient SO2 concentration during 3rd trimester of pregnancy * Random effect model

22. Dose response curves for association between risk of premature birth and BS during 1st trimester of pregnancy

23. Dose response curves for association between risk of premature birth and BS during 3rd trimester of pregnancy

24. Risk of premature birth associated with 10  g/m 3 increase in ambient BS concentration during 3rd trimester of pregnancy

25. CONCLUSIONS In Polish urban population: Ambient air pollution was not found a significant risk factor of fetal growth Ambient air pollution was not found a significant risk factor of fetal growth Air pollution with black smoke was found a significant risk factor of premature birth Air pollution with black smoke was found a significant risk factor of premature birth