1. MOTIC VM600 Virtual Microscope Development of Motic’s New Model; Features & Improvements, Model Strategy, and Model Competition Development of Motic’s New Model; Features & Improvements, Model Strategy, and Model Competition Motic International Dealer Meeting March 2009

2. Topics Covered 1.Motic VM Introduction: Hardware & Softwares 2.Application solutions: a.Clinical Diagnosis/ b.Consultation, Research c.Education 3.VM System Operation & software 4.Competitive Analysis

3. VM600-4 ： Digital Slide Scanner VM ： Digital Slide View software Digital Pathology Consultation & Communication Platform 1 、 DPCC （ Digital Pathology Consultation & Communication Platform ） Digital Slide Server System 2 、 DSS （ Digital Slide Server System ） Motic Products Solution www.moticpathology.com www.motic.com/dssweb

4. 4 Motic VM Components (Hardware & Scanning software))

5. Scanning Scanning Process Demo ：

6. Digital Slide View Demo

7. Motic Pro 285 CCD 1. Motic 285A ： 2/3 ", 1360 x 1024, 6.45  m x 6.45  m MCAM285 Technical Data Item MCAM285 Sensor Size2/3"CCD Resolution1.4 mega pixels, 1360 X 1024 pixels Pixel Size 6.45  m x 6.45  m Frame Rate15 fps / second ShutterElectronic Dynamic Range>44db S/N Scanning SystemProgressive Minimum Illumination≈3Lux USB InterfaceUSB2.0(480Mbit/sec VoltageDC 5V± 5% Operating Current≈260mA Power Consumption≈1.3W Operating Temperature 0 ℃ -50 ℃ Storage Temperature 0 ℃ -60 ℃ Relative Humidity40%-80% OS recommendedWINDOWS2000 / WINXP / VISTA

8. Objective: 20x ； Specimen ： 10mmx10mm ； Scanning Method: Standard ； Speed ： About 4 min Scanning Speed

9. VM600 Stage Configuration X - 272mm ； Y - 196mm ； Z - 93mm ; Travel range of 80mm by 24mm Stage Accuracy: 1.5625um for x/y –axis,; 0.015um for z-axis; Relocation Accuracy: <1um

10. Motic VM600 Recommended PC Specifications Workstation System: Windows XP Professional Intel Core(TM) 2 processors 4GB RAM 300GB disk storage 22 “ Monitor(or larger Optional)

11. Motic VM Scanning Methodology 1. High Precision Auto –Focus every Image, high quality 2. Standard ： Build Scanning model, good quality with faster scanning speeds 3. ROI （ Region of Interest ） : Scan whole slide with low magnification(2x or 4x) first, then scan ROI with higher magnification. Small Digital slide Size(<10M), useful and convenient for pathology or educational applications (Motic only feature) 4.Multilayer Focus: Multilayer focus and amalgamation each tiled image. Very high quality,especially for thick glass slide (but may be too slow for most applications)

12. Multilayer Focus Scanning

13. Multi-Layer Amalgamation

14. Living specimen Freezes Tissue Traditional Pathology Workflow Fix, Dehydrate, Embedding…. Histo- processing SlideStaining Slides Surgery CenterPathology Center Pathologist Center Pathology Diagnosis Tissue specimen Pathology Education

15. Digital Slides Digital Pathology Solution: Adjusting Standard Workflows Living specimen Fix, Dehydrate, Embedding…. Histo- processing SlideStaining Tissue specimen Surgery Center Pathology Center Freezes Tissue Pathologist Center Pathology Diagnosis &Analysis Slide Image Analysis Workflow Management Remote-Consultation Education

16. Information Workflow, including Digital Slides… Integrated Patient records (HIS/PACS…) Education & Clinical Remote-Consultation Image analysis Future Digital Pathology Directions

17. Microscope MOTIC’s Digital Development Makes the VM600 The Next Logical Progression … Digital PathologyMicro+Camera

18. VM Application Solutions VM Application Solutions

19. VM600 Digital Slide Applications  Educational ()  Educational (Cell Morphology, Histology, Pathology, etc.)  Digital Slides Classroom Teaching  Remote Teaching and Learning  Virtual (Web) Teaching Lab for Images view and conference  Clinical Diagnosis(Pathology)  Digital Images Data and workflow Management  Remote Consultation  Digital Slides Conference  Aided Diagnosis  Research  Digital Slides Data  TMA  Image analysis  Pharmaceuticals

20. VM Educational Applications VM Educational Applications

21. Digital slides Education System for Pathology and Histology Teaching  Classroom Teaching 1. Digital Slides reduce concerns about slide making, loss, breakage or fading; 2. Archive and share critical slides; 3. Built-in Digital Slide information management to reduce teacher prep time for course development and dedicate more time to viewing  Digital slides Testing 1. Manage digital slides to create a test library as an effective means for distributing testing materials; 2. Auto testing  Digital Slides gallery( Web view) 1. Anywhere, anytime access via internet on web, Pre- learning and Review ; 2. Improving the teaching level and learning effectively;

22. Motic VM IE View DSS Server workstation IE View Motic Digital Slides Server Software System Motic Digital Slides Server Software System (DSS) Lan/Internet Web-Based

23. View by annotation, convenient for teaching and learning Motic Digital Slides Server System Motic Digital Slides Server System (DSS) Web-Based

24. Incorporating VM600 with Motic Net as an effective teaching tool.. Education (VM600 with Motic Net)

25. For Pathology Diagnosis (Secondary) & Consultation

27. Motic VM Feature: Observe slide by Motic VM whiling or after scanning the slide,it is the best way for beginning of diagnosing training

28. Digital Pathology Consultation & digital slide Communication Platform LAN or Internet （ ADSL ） LAN or Internet （ ADSL ） Motic VM Remote Experts On business or at home LAN or Internet （ ADSL ） LAN or Internet （ ADSL ） DPCC Platform Consultation station Remote Consultation Center Remote Consultation Center

29. Motic DPCC Platform Web Address http://www.moticpathology.com

30. HIS PIS Patient Information Info Management Workflow DICOM Digital Slides Report Remote Consultation Internet) Conference Motic VM Digital Pathology Information Workflow