1. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Chapter 10 Lymphatic System Diseases and Disorders

2. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Anatomy and Physiology Lymph vessels, ducts, and nodes Protects body from infection by filtering bacterial and nonbacterial products Prevents waste products from entering circulatory system Dependent on vascular system Lymph is clear fluid

3. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Lymph and Blood Vessels

4. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Anatomy and Physiology Two divisions of lymph system: –Right lymphatic duct drains lymph from head, upper torso, and right arm –Left lymphatic duct Also known as thoracic duct Rest of body drains through this duct –Organs related to lymph system: Tonsils, thymus gland, and spleen

5. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Animation Click Here to Play Lymphatic System Animation

6. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Common Signs and Symptoms Enlarged lymph glands or nodes, fever, fatigue, and weight loss Most diseases of lymphatic system related to diseases of other systems

7. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Common Signs and Symptoms Lymphocytosis –Increased WBCs Lymphocytopenia –Decreased WBCs

8. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Diagnostic Tests Complete blood count (CBC) with differential Lymphangiography –X-ray of lymph system after dye injection MRI CAT scan Biopsy of lymph nodes

9. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Common Diseases of the Lymphatic System Lymphadenitis –Inflammation of lymph glands –Symptoms: Swelling Pain Tenderness

10. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Common Diseases of the Lymphatic System Lymphangitis –Swelling of lymph vessels due to inflammation caused by strep infections following trauma –Characterized by red streak at bacterial entry extending to area of lymph node

11. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Common Diseases of the Lymphatic System Lymphangitis –Other symptoms: Fever Chills Malaise Cellulitis

12. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Common Diseases of the Lymphatic System Lymphangitis –Treatment: Antibiotics Warm, moist packs Elevation of affected area

13. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Common Diseases of the Lymphatic System Lymphedema –Abnormal collection of lymph fluid in extremities –Possible causes: Surgery or radiation treatments Pregnancy Burns Trauma

14. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Common Diseases of the Lymphatic System Lymphedema –Treatment: Antibiotics Compression therapy Surgical intervention depending on cause

15. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Lymphedema Photo courtesy Mark L. Kuss

16. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Common Diseases of the Lymphatic System Lymphoma –Neoplasms affecting lymphoid tissue –Affects normal lymphocyte production leading to impaired immunity –Most common type of blood cancer in United States

17. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Common Diseases of the Lymphatic System Mononucleosis –Viral infection –Somewhat contagious –Also known as kissing disease

18. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Rare Diseases Kawasaki disease –Also known as mucocutaneous lymph node syndrome –Acute febrile disease –Found mostly in children

19. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Rare Diseases Kawasaki disease –Symptoms: Rash similar to scarlet fever Edema of feet and hands Lethargy Congestion –Supportive treatment

20. Copyright © 2010 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Effects of Aging Decreased ability to produce antibodies –Thus, more prone to infections Increased susceptibility to autoimmune disorders Impairment of vascular system also impacts function