12. Specific weight Size Plasma1,0261-4 μm Platelets1,0406-10 μm Lymphocytes1,07710-30 μm Monocytes1,08010-15 μm Eosinophils1,0829-15 μm Neutrophils1,08812-15 μm Erytrocytes1,1006-8 μm

17.  IgG 1, 2, 4  Types of immune complexes containing  Trombocytopeny refractory autoimmune  Familial Hypercholesterolemia

19.  RBC exchange  Leukocytapheresis  Extracorporeal photopheresis  Platelet apheresis  Thrombocytapheresis  Erythrocytapheresis  Plasmapheresis  LDL apheresis  Plasma exchange

20.  Crystalloid  Albumin 5%  FFP  colloidal Starch ( 3-6 % )  ACP ( acid citrate dextrose )  Heparin

21. Category I Category I Category II Category II Category III Category III Category IV Category IV

22. Acute inflammatory demyelinating polyneuropathy (Guillain-Barré syndrome) (plasma exchange) ANCA-associated rapidly progressive glomerulonephritis (Wegener’s Granulomatosis) (plasma exchange) ANCA-associated rapidly progressive glomerulonephritis (Wegener’s Granulomatosis) (plasma exchange) Anti-glomerular basement membrane disease (Goodpasture’s syndrome) (plasma exchange) Anti-glomerular basement membrane disease (Goodpasture’s syndrome) (plasma exchange) Babesiosis (RBC exchange) Babesiosis (RBC exchange) Cardiac allograft rejection prophylaxis (photopheresis) Cardiac allograft rejection prophylaxis (photopheresis) Chronic inflammatory demyelinating polyneuropathy (plasma exchange) Chronic inflammatory demyelinating polyneuropathy (plasma exchange) Cryoglobulinemia (plasma exchange) Cryoglobulinemia (plasma exchange) Cutaneous T-cell lymphoma; mycosis fungoides; Se´zary syndrome, erythrodermic (photopheresis) Cutaneous T-cell lymphoma; mycosis fungoides; Se´zary syndrome, erythrodermic (photopheresis) Homozygous familial hypercholesterolemia (plasma exchange or selective adsorption) Homozygous familial hypercholesterolemia (plasma exchange or selective adsorption) Hyperleukocytosis, leukostasis (leukocytapheresis) Hyperleukocytosis, leukostasis (leukocytapheresis) Hyperviscosity in monoclonal gammopathies, treatment of symptoms (plasma exchange) Hyperviscosity in monoclonal gammopathies, treatment of symptoms (plasma exchange) IgG/IgA, or IgM type of paraproteinemic polyneuropathy (plasma exchange) IgG/IgA, or IgM type of paraproteinemic polyneuropathy (plasma exchange) Myasthenia gravis (plasma exchange) Myasthenia gravis (plasma exchange) Renal transplantation, antibody mediated rejection (plasma exchange) Renal transplantation, antibody mediated rejection (plasma exchange) Sickle cell disease: red blood cell exchange for acute stroke Sickle cell disease: red blood cell exchange for acute stroke Thrombotic thrombocytopenic purpura (plasma exchange) Thrombotic thrombocytopenic purpura (plasma exchange)

24.  Concentration-time  The initial concentration  Plasma volume replacement in time

26.  Citrate toxicity  Allergic reactions  Anaphylactoid reactions  Infection  Deletion of drugs  Anemia & hemolysis  Hypotermia  Hypovolumy