1. Life Sciences Trend Analysis 2013 SWITZERLA ND

2. About Us The following statistical information has been obtained from Biotechgate. Biotechgate is a global, comprehensive, Life Sciences database encompassing the Biotechnology, Pharmaceutical and Medical Device industries. www.biotechgate.com www.biotechgate.com The Swiss Life Sciences Database is a part of the global Biotechgate and is brought to you in partnership with Swiss Biotech Association, Biotechnet, BaselArea, Life Sciences Zurich, and SIX Swiss Exchange. www.swisslifesciences.comwww.swisslifesciences.com Biotechgate is owned and operated by Venture Valuation AG, a Zurich based company specializing in independent assessment and valuation of technology-driven companies in high growth industries, such as the Life Sciences (Biotech, Pharma, Medtech), ICT, high-tech, Nanotech, Cleantech and Renewable energy. www.venturevaluation.comwww.venturevaluation.com

3. Status of the Sector 2012 Statistics Switzerland 2013 Statistics 318Total Biotech Companies345 95Biotech - Therapeutics102 163Biotech - R&D Services178 60Biotech - Other65 94%Percentage of SME's89% 4%Percentage of Publicly Owned Companies4% USD 159 M in 2011 Financing/Capital Raised USD 117 M in 2012 122Licensing Opportunities171

4. Key Activities of Biotechnology Companies Historical Data Subsector20132012 Bioinformatics & Bioelectronics5% Contract Research & Manufacturing 14%13% Diagnostics and Analytical Services 20% Genomics & Proteomics5% Other Services and Suppliers24%25% Therapeutics16% Other16%

5. Company Foundation Timeline

6. Company Ownership Historical Data Subsector20132012 Private/ Independent79%81% Public4% Subsidiary17%15%

7. Sources of Company Foundations Historical Data Company Foundation20132012 Independent foundation44%50% Merger1%2% Spin-off from company3%4% Spin-off from public institution / NPO2% Spin-off from university15%22% Subsidiary14% Other5%

8. Number of Employees Historical Data No. of Employees20132012 1-1034%33% 11-5040%44% 51-20015%17% Greater than 20011%6%

9. Products in the Pipeline

10. Financing Rounds in Switzerland & 3 Major Financing Rounds Financing for 2012/2013 Private Biotech Companies Major Financings in 2012/2013SectorUSD M Biocartis SA Biotech – Therapeutics & Diagnostics 45 GenKyoTex SA Biotech – Therapeutics & Diagnostics 27 PIQUR Therapeutics Ltd. Biotech – Therapeutics & Diagnostics 15

11. About Biotechgate Biotechgate contains over 29’000 high quality company profiles which include company descriptions, contact information, product pipeline information, financing rounds and management details. Profiles are regularly updated by the companies themselves, as well as by an experienced database team, to ensure the accuracy and relevance of the data. To register for free or learn more about the different subscription options, please visit www.biotechgate.com. www.biotechgate.com

12. Terms of Use The “Swiss Life Sciences Trend Analysis” is based on data entered in the Biotechgate Database available at www.biotechgate.com. The statistics and graphs in this presentation are based on figures and information entered in this database and we do not guarantee any accuracy hereof. The use of the figures and graphs provided in this report is free of charge for any presentations as long as www.biotechgate.com is clearly cited as the source. For all other uses please contact us for terms and conditions. Biotechgate c/o Venture Valuation VV AG Kasernenstrasse 11+41 (43) 321 86 60 8004 Zurichinfo@venturevaluation.com Switzerlandwww.venturevaluation.com