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Surgical treatment for morbid obesity
General Surgery Department Surgical treatment for morbid obesity Ram Elazary, MD General Surgery Department Hadassah Medical Center Campus Ein Kerem
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Prevalence of obesity in Israel
60% of total population Morbid obesity: 9% of women and 4% of men
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Definitions Body mass index (BMI) = Kg/Height2 BMI > 40
35 < BMI < 39.9 and co-morbidity
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Co-morbidity related to BMI
60% 28% 16% 41% 51% 50% 44% 40% 32% PERCENT AFFLICTED 30% 26% 24% 23% 10% 14% 20% 18% 15% 10% 7% 4% 0% Diabetes Asthma Arthritis High Blood Pressure BMI < 25 25-30 30-40 BMI > 40
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Morbid obesity and loss of years of life
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Bariatric surgery (US)
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Bariatric surgery (Hadassah)
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Co-morbidity of Morbid Obesity
Hypertension Type 2 Diabetes Mellitus Hypercholesterolemia Orthopedic disease (Osteoarthritis, Back pain) Obstructive sleep apnea Venous insufficiency Fatty liver disease
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Surgery at Hadassah Sleeve gastrectomy Gastric bypass
Revision, conversion and reverse surgery
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Laparoscopic Surgery
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Advantages of laparoscopy
Less pain, early mobilization, better cosmesis
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Minutes post surgery…
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Decision making (risk stratification)
Benefit
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Success rate Weight loss vs cure of co-morbidity
Side effects (vomiting, reflux) Gastric band <80% Sleeve gastrectomy 90% Gastric Bypass 90-95%
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Sleeve Gastrectomy Low volume stomach Reduces hunger No malabsorption
Loss of 50-70% of excess body weight Relatively new procedure Morbidity 1-2%
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Roux en Y Gastric Bypass
Gold standard Low volume pouch Reduces hunger No malabsorption Loss of 50-70% of excess body weight More than 40 years of experience Morbidity 1-2%
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Post operative course Admission for 3 days
No urinary catheter or Naso-gatric tube Resuming fluids the day after surgery Discharged with liquid diet for 10 days
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Candidates for surgery
There is no age criteria Failed previous weight loss diets Strict BMI criteria Compliance
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Decision of which operation
Patient preferences Co-morbidity Laboratory results Imaging studies Overall risk
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Pre-operative studies
Swallowing contrast study or endoscopy Blood tests Abdominal sonography Chest X ray, EKG Psychiatric evaluation Dietician evaluation Other studies tailored specifically to the patient’s medical condition
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Weight loss “slope” after surgery
Different between patients Relatively excessive during the first 3 months Continues till months post surgery Excess skin – plastic surgery
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Follow up after surgery
Multidisciplinary approach: Surgeon / Dietician / Psychologist 3 / 6 / 12 months regular follow up Designing a web/phone based follow up ( s, phone, Skype etc.)
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Case presentation – gastric bypass
39 yo M 112 Kg, 173 cm BMI 37.4 Morbid obesity related co-morbidity: Hypertension Type 2 Diabetes Mellitus Hypertriglyceridemia Fatty liver disease
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Medications – prior to surgery
Aspirin 100mg q24h Tritace 2.5mg q24h Metformin 850mg q12h Novorapid 10units q8h Lantus 18units q24h Lipitor 80mg q24h
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Blood test result – prior to surgery
Fasting Glucose 134 mg/dl ALT 71 units HbA1c 8 mg/dl LDL 160 mg/dl TG 178 mg/dl
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One year post surgery Weight 112 84 Kg BMI 37 28
Morbid obesity related co-morbidity: Hypertension cured Type 2 Diabetes Mellitus cured Hypertriglyceridemia improved Fatty liver disease cured
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Weight post surgery
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HbA1c post surgery HbA1c
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ALT post surgery Months post surgery
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Medications one year post surgery
Aspirin 100mg q24h Tritace 2.5mg Metformin 850mg Novorapid 10units Lantus 18units Lipitor 40mg q24h
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Case presentation – sleeve gastrectomy
36 yo M 150 Kg, 184 cm BMI Fasting GLU 104 HbA1c Triglycerides 165 אציג בפניכם חולה שעבר ניתוח שרוול קיבה ,בקבלתו בן 36 משקל 150 גובה 184 BMI 44.8 רמות סוכר 104 בדם HbA1c 6.6
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9 months post surgery – sleeve gastrectomy
Weight 150 95 Kg 150 Kg cm BMI Fasting GLU 104 HbA1c Triglycerids 9 חודשים לאחר הניתוח משקל 95.7 ירידה של 53 ק''ג מאז הניתוח בדיקות סוכר 75 5.4 HbA1c TG 80 אני חושב שזה הצלחה ל LDL 133
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If all our allegations are true, there are possibly measures that could be taken in order to prevent this deleterious local and remote effects, for example by neutralizing the xanthine oxidase by oxygen radicals scavengers, or preventing this drastic portal vein blood flow reduction
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