3. The Skeletal System: An organ system composed primarily of a variety of connective tissues. Bone makes up most of the skeleton system, but also includes the cartilage, joints and ligaments make up about 20% of the total body mass of the body

4. Characteristics of Osseous Tissue: Mostly intercellular material with a few cells (about 2/3 minerals/proteins and 1/3 cells) – Matrix: rich in mineral salts. Calcium and phosphorous are the primary minerals in osseous tissue. Fibers: collagen and elastin – Cells: Osteocytes, Osteoblasts, Osteoclasts

5. Basic types of osseous tissue: – Compact (or dense bone): dense, looks smooth, homogenous

6. Spongy (or cancellous bone) Found in interior of bone Has a good deal of open space filled with marrow – Trabeculae: small needle-like or flat pieces of bone that make up the interior of bone.

7. Trabeculae

8. Functions of Bones: Provide support, protection, movement: Framework that supports and protects soft organs, functions as levers to move the body. Serve as the body’s mineral bank – Can be released as ions into blood Serves as the body’s blood cell factory – Hematopoiesis: blood cell formation Occurs in the marrow cavities of certain bones Stores fat

9. Classification of bone: The 206 bones of the skeleton are classified by their shape; long, short, flat and irregular.

10. Long Bones: – Considerably longer than they are wide. They have a central shaft and 2 ends or extremities – Primarily compact bone, but may contain substantial amounts of spongy bone. – Includes the bones of the legs, thigh, arms, forearms, fingers, toes, bones of the hand and foot, and the collar bone.

12. Gross Anatomy of Long Bone diaphysis: The tubular central shaft of compact bone: – Surrounds the medullary cavity Medullary cavities in long bones contain fat (yellow marrow), with blood vessels and nerve cells. Epiphyses: The bone ends or extremities. – more expanded than the diaphysis – surrounded by thin layer of compact bone – interior compose of spongy bone In adults, the spongy bone in the head of the femur and humerus are the only areas in long bones that routinely produce new blood cells.

15. Epiphyseal line: remnant of the epiphyseal plate (or growth plate: where long bones lengthen)

17. Periosteum: double layered membrane covering the outer surface of the diaphysis – Outer layer: connective tissue w/ blood vessels, lymphatic vessels and nerves – Inner layer: elastic fibers, blood vessels, osteoblasts and osteoclasts (bone destroying cells) Growth, development, repair of bone is initiated from this double membrane. Provides an insertion of anchoring point for tendons and ligaments.

19. Endosteum: Delicate connective tissue membrane covering the internal bone surfaces – Covers trabeculae of spongy bone – Lines the canals that pass through the compact bone – Contains both osteoblasts and osteoclasts

20. Articular cartilage: cartilaginous covering of the epiphyseal surfaces where long bones articulate. – Glassy textured hyaline cartilage – Cushions bone ends and absorbs stress during joint movement.

22. Short Bones: cube-like bones whose external surfaces are covered with periosteum and internal surfaces with endosteum – mostly spongy bone, with compact bone making up their thin surface layer. – Sesamoid bones are a special type of short bone found embedded within a tendon. The patella is a sesamoid bone.

24. Flat Bones Thin, flattened and usually slightly curved bones; (external surfaces periosteum, internal surfaces endosteum). Have 2 roughly parallel compact bone surfaces with a layer of spongy bone between. Include the sternum, ribs and most skull bones flat bones such as the sternum are the most significant areas of blood cell formation.

26. Irregular Bones All have complicated shapes: bones that don’t fit into the other classes. (external surface: periosteum, internal surface: endosteum) mostly of spongy bone enclosed by thin layers of compact bone Include the vertebrae, the hip bones, and some skull bones. some irregular bones, such as the hip, also make blood cells.

28. Surface features of bone The external surfaces of bone are rarely smooth and featureless. They display projections, depressions, and holes.

29. Projections: A.K.A. processes; help form joints or are the sites of muscle and ligament attachment.

31. Processes that help form Joints Head: large rounded articular process Facet: smooth, nearly flat articular surface Condlye: rounded, knuckle-like process where one bone articulates with another Ramus: arm-like bar of bone

32. Processes that serve as sites for muscle and ligament attachment Neck: narrow part of bone between “head” and “shaft” Spine: sharp, slender process Crest: ridge of bone that is unusually narrow Trochanter: large projection for attachment of muscles (only example is on the femur) Tuberosity: large, rounded projection; may be roughened Line: narrow ridge of bone; less prominent than a crest Tubercle: small rounded projection or process Epicondyle: raised area on or above a condyle

33. Scapula

34. Femur

35. Rib

36. Depressions and openings: allow blood vessels and nerves to pass Meatus: canal-like passageway Sinus: cavity within a bone, filled with air and lined with mucous membrane Fossa: shallow, basin-like depression in a bone, often serving as an articular surface Fissure: narrow, slit-like opening Foramen: round or oval opening through a bone

37. sinuses

38. Meatus

39. Foramen

40. Fissure

41. Microscopic Structure of Bone Compact Bone: – Although it appears very dense, compact bone is riddled with canals/passageways that serve as conduits for nerves, blood vessels and lymphatic vessels

42. – The osteon or Haversian system is the structural unit of compact bone Functionally each osteon is a tiny weight-bearing pillar Each osteon is an elongated cylinder oriented along the long axis of the bone and consists of a group of hollow tubes of bone matrix (called lamella); one place inside the next.

43. Osteons – All the collagen fibers in a lamella run in a single direction – Collagen fibers in adjacent lamella run in different directions. – Lamella reinforce each other and make units called osteons – A central or Haversian canal runs through the core of each osteon; containing blood vessels and nerve fibers

44. – Perforating or Volkmann’s canals run at right angles to the long axis of the bone connecting the vascular and nerve supplies of the pariosteum to those of the Haversian canals and the medullary cavity – Both the Haversian/Volkmann’s are lined with endosteum

45. – Osteocytes lie in small concavities called lacunae at the junctions of lamellae – Canaliculi connect lacunae to each other and to the Haversian canal and also tie all osteocytes together, permitting nutrients and wastes to be easily relayed from one osteocyte to another.

46. Osteon

47. Spongy Bone – Consists of trabeculae Trabeculae contain irregularly arranged lamellae and osteocytes interconnected by canaliculi There are no osteons: nutrients reach the osteocytes by diffusing through the canaliculi from the marrow spaces between the trabeculae