1. HC70A Winter 2006 Genetic Engineering in Medicine, Agriculture, and Law Professor Bob Goldberg Course Administratorp

2. We Live in the Era of.... Genes & DNA Genetic Engineering Whole Genome Sequencing & Genomics Mammalian Reproduction & Cloning And the SYNTHESIS of These Technologies!!! Today

3. What Is A Gene? What Do Your Genes Look Like?

4. HC70A Winter 2006 Genetic Engineering in Medicine, Agriculture, and Law TAs Mike Gaviño Gloria Chu Course Administrator Jessica Luke Course Administratorp

5. HC70A Winter 2005 Genetic Engineering in Medicine, Agriculture, and Law Professor Bob Goldberg Class Announcements 1/10/06

6. Discussion Tomorrow Recombinant DNA Debate The Manipulation of Genes Read Papers Handed Out Today & Textbook Chapters 1-3 Be Prepared for Scientific & Ethical Discussion

7. RSVP (jluke@mcdb.ucla.edu) Dinners Prepare Good Questions NOVEL Chance For Intellectual Exchange

8. Using a Jellyfish Gene to Make Animals and Plants Glow!!!! Green Fluorescence Protein

9. Making a “GloFish”……….……Using Genetic Engineering & A Jellyfish Gene!!!! Making a “GloFish”……….……Using Genetic Engineering & A Jellyfish Gene!!!!

10. A “GloFish”Embryo!!!!!

11. A “GloFish!!!!!”

12. How About a GloFly!!!!!!

13. How About a “GloMouse!!!”

14. How About “GloMice!!!”

15. A GloPlant With the Same Jellyfish Gene What are the philosophical and biological implications of these experiments?

16. What Do These GloGene Experiments “Say” About Unity of Genetic Processes? What is the Hypothesis? What are the Predictions? What Experiment(s) to Test Predictions?

17. What are the Observations? What is Your Hypothesis? What are the Predictions? Scientific Process How Test Hypothesis? What are the Experimental Data? Have the Data Been Verified & Peer Reviewed?

18. What About Inserting Bacterial Genes Into Higher Organisms To Produce a Result With Significant Applications??

19. How to Make an Insect-Resistant Plant

20. Genetic Engineering a Plant to Resist Worms!

21. Max Smith Farmer What do Farmers Say About This Technology?

22. What Else Can Be Done With Genetic Engineering?

23. How About a “GloMonkey!!!” Using red fluorescence protein

24. Genetic Engineering for the Non-Science Major: Discovering Genes Required to Make a Seed Relating Molecular Biology to Society Bob Goldberg

25. A Three Part Program Designed to Teach Future “Decision Makers” About How Science is Carried Out……. Providing the Foundation Teach “Genetic Engineering in Medicine, Agriculture, & Law” to Non-Science Students and Entering Science Majors (HC70A-Winter) Teaching Undergraduates “How to Teach” Use Advanced Undergraduates as Teaching Assistants Provide a “Real-Life” Discovery Research Experience Establish Undergraduate Teams to Carry Out Discovery Research on “How to Make a Seed” Use Undergraduate Mentors to Lead Research Teams (HC70AL-Spring)

26. Giving Undergraduates a Unique Educational Experience Interactive “Team Approach” Socratic Style Teaching Method/Critical Thinking Discussion Taught as an Undergraduate Seminar Learn How to Read and Think About Science Discussion Taught By Undergraduate TAs Discuss the Social Implications of Genetic Engineering Simulate Real Situations with Plays and Docudramas Use Take-Home and Oral Exams/Group Learning Require an All-Class Film Project Bring Science into the Classroom (Fingerprint Class) Weekly Student Dinners Guest Speakers HC70A-Genetic Engineering in Medicine, Agriculture, & Law”

27. HC70A Winter 2003-2005 180 Students (125 UCLA+55 Kyoto)

28. What are the Genes Required to Make a Seed? Moving Undergraduates from the Classroom to the Laboratory An Intense Ten Week Experience!! Bigger Seeds More Seeds Increased Yield

29. HC70A & HC70AL 2003-2005 ~215 Students (180+35)