1. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002 Life Sciences, Genomics and Biotechnology for Health Dr Alfredo Aguilar Head of Unit Biotechnology and Applied Genomics Research Directorate General European Commission

2. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002 Framework Programme 2002-2006 Focussing and Integrating Community Focussing and Integrating Community Research To assemble a critical mass of resources and support integration of EU research capacities in 7 priority areas supporting policies and anticipating needs SME International cooperation JRC (non-nuclear research) Structuring ERA To structure the ERA in: Research & Innovation Training & Mobility Infrastructures Science & Society Strenghtening the ERA Foundations To co-ordinate EU research activities To support the development of research/innovation policies

3. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002 7 Priority Thematic Areas 1. Life Sciences, Genomics and Biotechnology 2255 for Health 2. Information Society Technologies 3625 3. Nanotechnologies, Multifunctional Materials and New Production Systems and devices 1300 4. Aeronautics and Space 1075 5. Food Quality and Safety 685 6. Sustainable Development,Global Change and Ecosystems 2120 7. Citizens and Governance in a Knowledge Society 225 Budget proposed (EUR million)

4. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002 Framework Programme 6 (2002-2006) Thematic priorities Focus on strategic areas where immediate and longer term integration of European research is needed to generate and sustain necessary critical mass New knowledge >> understanding >>application

5. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002 Priority ‘Life Sciences, Genomics and Biotechnology for Health’ To help Europe to exploit breakthroughs in decoding the genomes of living organisms for the benefit of : - public health - citizens - increase the competitiveness of European biotechnology industry

6. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002 Priority 1: Life Sciences, Genomics and Biotechnology for Health Advanced genomics and its application for health (1100 Millions Euros): Fundamental knowledge and basic tools for functional genomics in all organisms Applications of knowledge and technologies in the field of genomics and biotechnology for health Combating major diseases (1155 Millions Euros): Application-oriented genomic approaches to medical knowledge and technologies Confronting the major communicable diseases linked to poverty

7. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002 Fundamental knowledge and basic tools for functional genomics in all organisms Objective: Understanding of genomic information, by developing the knowledge base, tools and resources needed to decipher the function of genes and gene products. - Research actions: gene expression and proteomics - Structural genomics - Comparative genomics - Comparative genomics and population genetics - Bioinformatics - Multidisciplinary functional genomics approaches to basic biological process APPLICATIONS MedicineAgricultureQuality of LifeEnvironment

8. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002 Applications of knowledge and technologies in the field of genomics and biotechnology for health (i) Objective: Foster the competitiveness of Europe’s biotechnology industry by exploiting the wealth of biological data produced by genomics and advances in biotechnology. - Research actions: Technological platforms for the development in the fields of new diagnostics, prevention and therapeutic tools … with an active and early involvement of regulators, experts on ethics, patients and society at large. APPLICATIONS Health Care DiagnosticsCost Reduction Individualised treatment New drugs and therapies

9. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002  Technological platforms for developments in the field of new diagnostic, prevention and therapeutic tools : Applications of knowledge and technologies in the field of genomics and biotechnology for health (ii) Rational and accelerated development of new, safer, more effective drugs including pharmacogenomics approaches Development of new diagnostics Development of new in vitro tests to replace animal testing Development and testing of new preventive and therapeutic tools (such as somatic gene and cell therapies [stem cells therapies]) Immunotherapies Innovative research in post-genomics, which has high potential for application

10. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002 Application-oriented genomic approaches to medical knowledge and technologies Objective: to develop improved strategies for the prevention and management of human disease and for living and ageing healthy. Research actions: - Combating cardiovascular diseases, diabetes and rare diseases - Combating resistance to antibiotics and other drugs - Studying the brain and combating diseases of the nervous system - Studying human development and the ageing process - Combating cancer APPLICATIONS Bringing basic knowledge through to clinical applications Improved patient- oriented strategies

11. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002 Confronting the major communicable diseases linked to poverty Objective: To confront the global emergency caused by the three major communicable diseases HIV/AIDS, malaria and tuberculosis through the development of effective disease interventions, particularly for use in developing countries.

12. Science, research and developmentEuropean Commission Chile-EC S&T Agreement Brussels, 24 September 2002 Ongoing and coming trends... 7 June 2002 deadline for the “Invitation to submit Expressions of Interest”. November 2002, First Call for Proposals, Framework Programme 6 To keep you informed with the latest news… www.cordis.lu/fp6/eoi-instruments … and with the new instruments, rules for participation,… http://europa.eu.int/comm/research/nfp/networks-ip.html Help and information : for Priority “Life Sciences, Genomics and Biotechnology for Health”: rtd-genomics@cec.eu.int Opportunities for Life Sciences, Genomics and Biotechnology for Health in Framework Programme 6 (2002-2006)