1. Identify the chemical signal that is released by glands in the endocrine system Identify the structure that chemical messages bind to in order to initiate change in the body The disease diabetes is caused by a lack of a certain hormone in the body. Which hormone?

2. What is Diabetes? Read along Underline key points Answer the questions below

3. Examine This Diagram: Can you put the events in order?

4. What is happening here?

5. Disrupting Homeostasis…

6. How do we get back to normal after a change disrupts our homeostasis?

7. HOMEOSTASIS CHANGE RESPONSE CANCEL CHANGE Negative Feedback- Thermostat Decrease in temperature Increase in temperature Heater turns on Heater turns off

8. HOMEOSTASIS CHANGE RESPONSE CANCEL CHANGE Negative Feedback- Insulin

9. What is negative feedback? Provide an explanation in your own words on your notes Summarizing What We’ve Learned

10. Negative Feedback- response that reverses changes in the body to restore homeostasis. Summarizing What We’ve Learned

11. White Board Review Quick Check! After a question is presented, we will discuss in partners and write our answers on our “white boards” We will hold these up to show Ms. L if we are Endocrine Experts or Failing Feedback

12. 1.The ability of the human body to keep blood glucose within a fairly narrow range, despite constant changes in the environment, is an example of a) the human niche b) genetic evolution c) homeostasis d) thermocrine regulation

13. 2. Identify the structure in the human body that is the usual source of insulin. a)the pituitary b)the thalamus c)the hypothalamus d)the pancreas

14. 3. Insulin: a) Causes an increase in blood sugar b) Is released in response to a decrease in blood sugar c) Causes cells to use glucose d) Initiates the production of glucose

15. 4) A person with diabetes: a) does not make the hormone insulin b) does not make the hormone glucagon c) does not respond to insulin d) either a or c e) both a and b

16. 5.Which of the following is NOT an example of negative feedback. a)the body experiences a decrease in temperature, this initiates shivering which raises the internal body temperature b) Hormone A is released in response to an increase in blood pressure. This triggers the release of hormone B which increases the production of Hormone A c) Insulin is released in response to an increase in blood sugar. It decreases the amount of sugar in the blood and then is no longer released d)Hormone 2 is secreted in response to dehydration. This triggers the body to increase its water intake, which also stops the secretion of hormone 2.

17. HOMEWORK Remaining Classwork problems HW 2.6- Negative Feedback and Diabetes REMINDER: Presentation Dates –Muscular/Skeletal: WEDNESDAY 10/5 –Circulatory/Respiratory: THURSDAY 10/6 –Excretory/Digestive: TUESDAY 10/11