1. Main slide Cascara bark Names. Description and origin.
Constituents and uses.
Frangula bark
Constituents.
Medications and uses.
Kurchi bark
Names, description and origin.
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3. Outer part of the bark brown colour inner surface reddish brown
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5. Cascara bark :Cascara sagrada bark لحاء الشجرة المقدسة
Rhamnus purshianus
Family : Rhamnaceae
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6. Description Perennial trees Odor : slight . Taste : bitter.
The bark must be stored minimum one year before being used (more cathartic).
Origin: USA & Canada.
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7. Chemical constituents
Glycosides :anthraquinone group:
1.Cascaroside A & B (barbaloin)
2.Cascaroside C & D (chrysaloin)
USES
Purgative : for treatment of habitual constipation .
We add to the drug MgO ( magnesium oxide) to avoid bitter taste .
(dose 300mg)
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9. Frangula bark
Rhamnus frangula
Family : Rhamnaceae
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10. Description Perennial small trees . The bark color : dark brown .
Odor: slight .
Taste : bitter .
origin: Europe & Western Asia .
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11. Chemical constituents
Anthraquinone glycosides :
a. Frangulin
b. Gluco-frangulin
2. Free anthraquinone (emodin)
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12. Medications and uses Cascara and Frangula barks drugs:
Bilacton ®:Trima
Dragee
Cascara dry extract + Cortex Frangula + Phenolphthalein + Belladonna dry extract
Indication: constipation, acute and chronic.
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13. Holarrhena antidysenterica Family : Apocynaceae .
Kurchi bark
Holarrhena antidysenterica
Family : Apocynaceae .
Perennial trees 10 m.
The bark outer surface : reddish brown.
Inner surface : cinnamon brown .
Odor : slight .
Taste : acrid and bitter .
Origin: India .
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14. Chemical constituents
Alkaloid (steroidal group) Conessine
USES
Anthelmintic .
Anti-dysenteric .
Stomachic in small doses .
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