1. Medication Administration By: Diana Blum MSN NURS 1510

2. History Definition: Substance administered for diagnosis, cure, treatment, or relief of a symptom or for prevention of disease. Opium, castor oil, vinegar used in ancient times

3. Names Generic –Given before drug officially approved Official –Name under which it is listed in publications Brand/TRADE –Given my manufacturer –Several names if several manufacturers Chemical –Name by which the chemists know it

4. Legal Aspects U.S. drug legislation Sets official drug standards Defines prescription drugs Regulates controlled substances Improves safety Requires proof of efficacy Nurse Practice Acts Identify nursing responsibilities for administration and client monitoring

5. Standards Vary in strengths and activities Controlled by law NURSES can be punished if error made Controlled substances locked up in hospital

6. Effects of Drugs Therapeutic/Desired: what is intended or reason it was prescribed SE: secondary effect: effect that is not intended –May be harmful or harmless Adverse Effects: more serious side effects or a reaction to the drug Drug toxicity: related to overdose, ingestion when meant to be external in use, or build up in blood. Allergic Reaction: immune response to drug Anaphylactic Reaction: severe allergy to drug that could become fatal

7. Tolerance Person requires increase dose to maintain effectiveness (opiates, tobacco, etc) Cumulative effect: increased response to repeated doses. Toxic symptoms may occur. Idiosyncratic effect: unexpected result. Under response or over response Interaction: response to 2 drugs at once

8. Drug Misuse Improper use of common meds Abuse: inappropriate intake of drug Dependence: reliance of a drug may be physiologic or psychologic Habituation: feels better after taking drug Illicit: street drug

9. Actions of Drugs on the Body Half life: the time it takes for half of the drug to be excreted from the body If you don’t receive steady amount of the drug it concentration decreases. Onset of action: time it takes for the body to respond to drug Peak plasma level: the highest level achieved by a single dose Plateau: maintained level during a series of scheduled doses Agonist acts to respond to a substance Antagonist acts to inhibit a response to a substance

10. Pharmacokinetics Process by which drug is excreted absorbed distributed or biotransformed. Absorption: process of passing in the blood stream Distribution: transportation from site of absorption to site of action. Biotransformation: process that converts the drug to a less active form by way of a detox or metabolism Excretion: leaves the body

11. Factors that affect med action Developmental factors Gender Genetics/culture Diet Environment Psychologic Illness/disease Time of administration

12. Stock Supply: Bulk quantity Central location Not client-specific Unit Dose: Individually packaged Client-specific drawers 24-hour supply Medication Systems

13. Automated Dispenser: Password-accessible locked cart Computerized tracking Can combine stock and unit doses Self-Administration: Individual containers Kept at client’s bedside Medication Systems

14. Orders Types –STAT –Standing –PRN –Single Parts of the Order –Name –Date and time –Name of drug –Dose –Frequency –Route –why –signature TORB VORB Handwritten preprinted

15. Three checks: Before you pour: Check the medication label against the MAR After you pour: Verify the label against the MAR At the bedside: Check the medication again Nursing Considerations: Medication Administration Safety

16. Six Rights: Right drug Right client Right dose Right time Right route Right documentation Other Rights: Right reason Right to know Right to refuse Nursing Considerations: Medication Administration Safety

17. Routes PO SL Buccal Parenteral: SQ, IM, IV, intrdermal Topical

18. Equipment Preparation: Syringe/needle (size, gauge) Medication Preparation: Vials and ampules Reconstituting from powder Two medications in one syringe Never recap dirty needle Use the correct site Wrong site could mean wrong route Be familiar with the technique required for the medication (e.g., heparin, insulin) Parenteral Medication Administration

19. Use the six rights Calculate doses carefully; double-check with a second RN Watch for drugs with similar names Watch for clients with same last names Clarify illegible orders Know and use your resources Keep up with changes in medication orders Avoiding Medication Errors

20. Conversions

21. Systems of measurement Metric Ordered by units of 10 Decimal system Liter and gram are basic units kilogram milligram microgram milliliter

22. Apothecaries Older than metric Grain Minum Pound Pints quarts

23. Household Drops Teaspoons Tablespoons Cups Glasses

24. Metric: decimal system, most logically organized. Each unit is organized into units of 10. In X the decimal moves to the “R”; in division it moves “L” Basic measurement=meter(L), liter(volume), gram(weight) Equivalents of Measurements

25. Basic units: –Deci 1/10 or 0.1 –Centi 1/100 or 0.01 –Milli 1/1000 or 0.001 500mg or 0.5g, not 1/2g 10ml or 0.01L, not 1/100L –With fractions the zero is always place in front of the decimal to prevent error

26. In metric system, division or multiplication are used, ie, to change mg to g. divide by 1000 or move the decimal 3 points to the left To convert liters to ml, multiply by 1000 or move the decimal 3 points to the right Conversion in One System

27. To convert units of measurement within the apothecary or household system, must know the equivalent. Example: To convert ounces to quarts must know 32 oz is = to 1 quart To convert 8 oz to a quart measurement, divide 8 by 32 to get the equivalent, ¼ or 0.25 quart

28. When looking at a medication order, ask yourself 3 questions: What did the MD order? (desired quantity) What do I have on hand? (dose available) What conversion factor (conversion do I need? factor) Setting Up the Calculations

29. The desired quantity is the MD order, (10mg, v gr) The dose available is found on the drug label, (tablet, number of capsules, ml) *Remember, the quantity of tablets, capsules, or ml is always the numerator of the dose available; the amount (or dosage) is in the denominator

30. To decide which equivalent measure should be in the numerator and which should be in the denominator, look at the units of measure in the desired quantity. The units of measure in the desired quantity should be in the denominator of the conversion factor (i.e.,if the desired quantity is 100 mg and the equivalent conversion factor is 1000 mg = 1 g, then the conversion factor in fraction form should be 1 g / 1000mg

31. Desired quantity x Dose available X Conversion (if factor needed) = Amount to Administer This is a simple formula that uses ratio and proportions which will help you both correctly set up and solve dosage calculation problems Formula

32. MD order: ASA 300 mg q4h prn pain Drug label: ASA 1 tab = v gr Conversion factor: 1 gr = 60 mg 5gr x 1 tab x 60 mg = x 300mg 1 gr 5 x 1 tab x 60 = 300 tab = x 300 300

33. 300 tab = x 300 x = 1 tab continued

34. Another basic formula that can be used when preparing solid or liquid forms: Desire dose X Amt on hand = Amt to give dose Have Demerol 50 mg ordered comes in 100 mg vial in I cc More Formulas

35. Amount in cc’s X drip factor = gtt/min time in minutes Rate of infusions

36. 1 gram (G) = 1000 milligrams (mg) 1000 micrograms (mcg) = 1 mg 60-65 mg = 1 grain (gr) 1 fluid ounce = 30 ml or 2 tablespoons 1 teaspoon = 5 ml 1000 ml = 1 quart or 1 liter 1 kg = 2.2 pounds (lb) 1 inch = 2.54 cm 1 mL=15 gtts 30mL=1 ounce 1 tbsp= 15mL Conversions to know