1. Chapter 7 Diseases of the Blood

2. Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc. 1 Terms  Erythrocytes: Red blood cells  Hemoglobin: Protein in red blood cells  Anemia: Condition of reduced numbers of red blood cells  Hypoxia: Lack of oxygen in blood cells  Hemolysis: Red blood cell death  Pernicious anemia: Deficiency of Vitamin B12 which must be supplied by diet – body does not produce its own

3. Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc. 2 Terms  Leukocytes: White blood cells  Neutropenia: Reduction in circulating components of white blood cells  Age-related Anemia: is most common in persons greater than 75 years of age due to blood loss, nutritional deficits, chronic illness and chronic renal failure  Lack of white blood cells: Are generally secondary to cancer treatments, malignancy, and nutritional anemias

4. Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc. 3 Signs and Symptoms  Anemia: Iron deficient, of chronic disease and folic acid deficiency – Fatigue, SOB, decreased exercise tolerance  Pernicious anemia: Abdominal distress, nausea, vomiting, burning of tongue  Sickle cell anemia: pallor, SOB, fatigue, painful sickle cell crisis  Thalassemia (defective hemoglobin): Pallor, fatigue, SOB

5. Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc. 4  Polycythemia vera: Dizziness, headaches, and visual disturbances (treat with chemo, leeches)  Hemophelia A: Bleeding, genetic  Von Willebrand’s disease: Genetic, platelet adhesion causes bleeding  Neutropenia: Infection, fever, skin inflammation