1. NANODETECTOR Ultrasensitive plasmonic detection of single nanoparticles Representative of the project coordinator: Dr. S. Nizamov NanoDefine NSC workshop, NRCWE, Copenhagen, June 6 th 2014

2. Ultrasensitive plasmonic detection of single nanoparticles … NanoDefine NSC workshop, NRCWE, Copenhagen, June 6 th 2014 FP7-NMP-2011 SME-targeted collaborative project NMP.2011.1.3-1: New methods for measuring, detection and identification of nanoparticles in products and /or in the environment Project duration: 42 months, June 2012 - November 2015 EU Contribution: 2.968.000 € BTU-CS: 441.400 € Other research institutions: 859.000 € SME's: 1.667.600 € Coordinator: Brandenburg University of Technology Cottbus–Senftenberg (former Lausitz University of Applied Sciences) Prof. V. M. Mirsky Partners: Leibniz-Institut für Analytische Wissenschaften (Germany) (ISAS) Fraunhofer-Institute for Biomedical Engineering (Germany) (IBMT) Imperial College London (United Kingdom) Mivitec GmbH (Germany) Hybrid Integrated Technologies Ltd (Czech Rep.) (HIT) Optolita (Lithuania) Phasis S.a.r.l. (Switzerland) MBN Nanomaterialia S.p.A. (Italy) Upperton Ltd. (United Kingdom)

3. Ultrasensitive plasmonic detection of single nanoparticles … NanoDefine NSC workshop, NRCWE, Copenhagen, June 6 th 2014

4. Ultrasensitive plasmonic detection of single nanoparticles … NanoDefine NSC workshop, NRCWE, Copenhagen, June 6 th 2014

5. Ultrasensitive plasmonic detection of single nanoparticles … NanoDefine NSC workshop, NRCWE, Copenhagen, June 6 th 2014

6. Ultrasensitive plasmonic detection of single nanoparticles … NanoDefine NSC workshop, NRCWE, Copenhagen, June 6 th 2014 WP2: Theory WP4: Selective surface coatings

7. Ultrasensitive plasmonic detection of single nanoparticles … NanoDefine NSC workshop, NRCWE, Copenhagen, June 6 th 2014 The NANODETECTOR technology is a unique technique to observe binding of single nanoparticles with different surfaces in real time in native media Using of different surfaces allows us to distinguish different nanoparticles Image from nanoparticles contains information on the size and material of nanoparticles Very large detection area (~ 1 mm 2 ) allows to detect binding of a few nanoparticles in the very high dynamic range – from 1 nanoparticle up to hundreds thousands of nanoparticles The technology is realized as a laboratory prototype Summary Topics of interest: The validation of the device performance requires reliable reference samples of different nanoparticles Extension of the application fields for NANODETECTOR technology (for example, detection of viruses or other biological nanoparticles or investigation of interaction of engineered nanoparticles with biomimetic surfaces)

8. Ultrasensitive plasmonic detection of single nanoparticles … Thank you for attention! NanoDefine NSC workshop, NRCWE, Copenhagen, June 6 th 2014 Contact: mirsky@b-tu.de Web-site: www.nanodetector.eumirsky@b-tu.dewww.nanodetector.eu Participants of Nanodetector project at kick-off meeting, Senftenberg - 2012