1. ORGANIZATIONAL STRUCTURES PROMOTING RESEARCH, TRAINING, AND TECHNOLOGY TRANSFER IN MOBILITY Michael Boninger, Rachel Cowan, B.J. Fregly

2. Outline  Needs  What we saw / What worked  Research  Training  Technology Transfer  Gap Analysis - What was missing

3. Education Technology Transfer Research

4. Over 40 million Americans live with a disability Disability in the form of limited activities and restricted participation in social life is not an unavoidable result of injury and chronic disease. It results, in part, from choices society makes about working conditions, health care, transportation, housing, and other aspects of our environment. IOM Report - 2007 Need

5.  To ameliorate disability we must  Conduct high quality research  Transfer the research to clinical practice  Barriers  Lack of well trained researchers  Technology transfer  Changing clinical practice  Small populations with low income

6. Education

7. NOVEL EDUCATIONAL APPROACH Etienne Burdet, Imperial College

8. New course at Imperial College

9. Director : Wafa SKALLI ARTS ET METIERS PARISTECH BIOMECHANICS LABORATORY

10. Laboratories  LBM Education: Msc, PhD  Areas: Musculoskeletal, Modeling and clinical evaluation, Biomechanics: Sport, health and safety, Biomechanics and nervous system: motion analysis and restoration  International masters degree program in Biomedical Engineering  Collaboration between ParisTech and Paris Descartes Medical University  Admits half of students with engineering background and half with clinical background Education

11.  Medicine 2010  KVT - Clinical Science and Technology (2008)  Sports candidate (2008)  Sports bachellor (2007)  Medicine with indus. specialis. (2006)  BSc+MSc. in BME (2000)  Master in health informatics (1995)  Ph.d. i Biomedical Science and Engineering (1993)  Medicoteknik: BME MSc (1978) Problem Based Learning (PBL) Tell me and I will forget, Show me and I will remember, Involve me and I will understand, Old proverb Step back and I will act. EDUCATIONS PBL Education at HST

12. Education Summary  Structure to support the highest quality education  Multidisciplinary Clinicians & Engineers  Proximity  Experiential Problem based learning  Critical Mass

13. Technology Transfer

14. UNIVERSITY OF TWENTE Enschede, The Netherlands

15. MIRA  MIRA cuts across all departments, gathering expertise from many organizations and assisting them in bringing technology to market  MIRA currently has 250 researchers and will likely add 150 more in the next few years.  8 spin off companies to date and plan to have 3- 5/year moving forward.  Researchers may obtain stake in these companies, that are primarily funded by outside investors  MIRA’s role is helping bring research to a marketable point and connecting investors with researchers.

16. Demcon – advanced mechatronics  University of Twente spin off company (1993)  Incubator company  Brings products to market – up to first run series  Typically, a small or medium sized company has a problem and contracts with Demcon to provide a product solution.

17. RoboNED  Internal Dutch industry/academic/consumer innovation partnership supported by the Dutch government Develop a strategic robotic research agenda for the Netherlands. identify existing robotic research themes and research themes to pursue ultimate goal of commercially viable products. Cowan

18. LEO – Center for Service Robotics - notes  The Leo Center for Service Robotics is a newly formed collaborative offshoot of RoboNED. The LEO Center is located at University of Twente and includes a physical collaborative space. LEO has identified three service robotic themes: Medical (surgical, rehabilitation, prosthetics, etc…);  http://www.leo-robotics.eu/index.html http://www.leo-robotics.eu/index.html Cowan

19. HOCOMA - ADVANCED FUNCTIONAL MOVEMENT THERAPY Peter Hostettler, PhD & CEO, and team, Zurich Structural

20. Commission for Technology and Innovation  Joint projects between Swiss universities and companies, funded by Swiss government, to support the commercialization of new technologies.  Hocoma projects funded and realized through CTI:  Lokomat  Assessment Tools for Lokomat  Backtrainer: Augmented Feedback based Therapy for Low Back Pain  Hocoma has multiple relationships with Universities and rehabilitation centers

21. HANDICOM – NEW TECHNOLOGIES FOR INDEPENDENCE Prof. Mounir Mokhtari, Paris Structural

22. Reciprocal Patent Relationship  Telecom SudParis and Virginia Tech have a reciprocal relationship whereby:  Virginia Tech showcases Telecom SudParis patents in the United States.  Telecom SudParis showcases Virginia Tech patents in France.  Goal is to increase patent exposure to other countries so as to maximize the likelihood of product development for improved healthcare.  Current focus is on development of wearable systems to improve patient monitoring and safety in the field.

23. Technology Transfer - Summary  Structure to support technology transfer  Industry, research partnerships  Government support  Regulatory and business expertise  Proximity  Gap  Conflict of interest/solid research

24. Cooperation

25. RESTORATION OF HUMAN MOTOR FUNCTION from Neurorobots to Motor Neuroprostheses J.L. Pons

26. European co-operation Rehab. Centres: RRD Rehab. Robotics: UoR EMG: AAU & U. Maribor EEG: TUGraz & EKUT FES: U. Belgrade Robotics: TUDelft Motion analysis: URT Industries: Prosthetics: Ossur Textiles: Smartex FES: UNA Sistemi EEG: gTec EMG: OT Bioelec Industries: Prosthetics: Ossur Textiles: Smartex FES: UNA Sistemi EEG: gTec EMG: OT Bioelec Hospitals: H. Erasme FSL Hospitals: H. Erasme FSL

27. INSTITUT FOR SUNDHEDSVIDENSKAB OG TEKNOLOGI AALBORG UNIVERSITY AALBORG, DENMARK DEPT. OF HEALTH SCIENCE AND TECHNOLOGY

28. Networking Mediconet Handiatek VCHI BioMedCom CHAT Center for ST V-CenTAH DMTS DSMI IDA-Sund Entrepeneurship Incubator at HST Innovation office at HST Spinn Out’s from HST Judex Datasystemer Neurodan – Otto Boch Ditens A/S Nemomed Mermaid Care ”AalQTeq /GE-Healthcare” TKS Cardiosound Collaborations Novo Nordisk RTX Coloplast Lundbeck Pfitzer Radiometer WM-Data Systematic ….. Innovation Your name here Research Dissemination – External Relations

29. SENSORY-MOTOR SYSTEMS LAB, ETH, ZURICH Prof., Dr. Robert Reiner

30. MIMICS  Multimodal Immersive Motion rehabilitation with interactive Cognitive Systems  Funded by European Union – Seventh Framework Program  Lokomat multimodal project observed at ETH http://www.mimics.ethz.ch/index.php?page_id=0

31. MIMICS  Key structural/organizational property  Technical, Clinical, and Industry partners involved  Expected to end in a commercial product  Pathway from technical development through clinical evaluation and commercialization is well defined  40% non-competitive internal, a part of his faculty package  Allows pilot development which translates into external funding  Goal is REAL products, so a balance must occur b/t discovery based learning & having to become competent in the multiple fields

32. Cooperation – summary  Cooperation Needed for  Effective clinical trials  Specialized expertise  Feeds  Education  Research  Technology Transfer  Forced by EU funding mechanisms

33. Cooperation - Gap  Balance of Cooperation and Competition  Forced versus real

34. Research

35. ORTHOPAEDIC SURGERY AND REHABILITATION Maria Benedetti, M.D. and Alberto Leardini, Ph.D., Bologna

36. Rizzoli Institute Overview  Surgeon, physiatrist, and biomedical engineer all working in same lab and sharing one office space.  Research activities span from before surgery to rehabilitation activities following surgery.  Focus on movement analysis of the lower limb and more recently on the trunk for low back pain.  Surgeon does a combination of research and clinical duties (50-50).  Hospital sees over 150,000 patients per year.

37. Brian Caulfield, Academic Director

38. TRIL Centre  Looks at the physical, social and cognitive consequences of ageing and develops technologies to address them.  Collaboration between researchers in academic, clinical and industry settings (ethnographers, clinicians, and designers).  Novel bio-psycho-social cohort data-set & technology platforms.  Ethnographers spend extended time understanding end users day-to-day lives. Helps to identify opportunities to put technologies.  Learn from our users – committed to a user-centered approach to technology development.

39. Research Summary  Infrastructure to support the highest quality research  Multidisciplinary Clinicians & Engineers Proximity We need to think of additional disciplines.  Gap  Multiple groups repeating work

40. End user input End user as investigator End user as student Many labs were not truly accessible What was missing

41. Thank you