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UCLA Nanoscale Measurement System March 18, 2005 Nanoscale Measurement System Non-confidential summary of UCLA technology available for licensing, Case.

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Presentation on theme: "UCLA Nanoscale Measurement System March 18, 2005 Nanoscale Measurement System Non-confidential summary of UCLA technology available for licensing, Case."— Presentation transcript:

1 UCLA Nanoscale Measurement System March 18, 2005 Nanoscale Measurement System Non-confidential summary of UCLA technology available for licensing, Case reference: LA2004-660 March 18, 2005 Ken Polasko Business Development Officer Office of Intellectual Property Administration KPolasko@ResAdmin.UCLA.edu www.research.ucla.edu/oipa (310) 794-8087

2 Nanoscale Measurement System Markets  Force and displacement characterization tools for the nanotechnology market. Background  Construction of hybrid bio-nanosystems relies on measuring and optimizing forces and displacements at the molecular level.  The measurement of the forces and displacements involved when attaching biological material to inorganic material or micro electro mechanical systems (MEMS) is becoming an increasing import design capability. Problem  Conventional force transducers (e.g. load sensors) have been the choice for the measurement of forces however these sensors do not have the required sensitivity.  Conventional force microscopy relies on cantilever torsional modes for measuring forces along the surface plane, implying in poor visualization and sensitivity.  Optical tweezers have been the choice for the measurement of forces produced by single molecules however this techniques has limited force range (pN).

3 Solution  Prototype has been fabricated that can detect forces of ~ 0.2 nN and a corresponding displacement of ~ 40 nm.  The prototype incorporates a novel illumination system that permits excellent visualization of biological material.  The system design permits flexible handling of liquids.  This system fills the gap between existing tools for measuring forces associated with biological elements and purely atomic measurement systems. Nanoscale Measurement System

4 Technological Status ResearchDevelopmentCommercialization Discovery Technical Feasibility IntegrationPrototypeProduction Nanoscale Measurement System

5 Inventors and Collaborators  Professor Carlo Montemagno, Department of Bioengineering & Biomedical Engineering  Professor Jacob Schmidt, Department of Bioengineering & Biomedical Engineering  Professor Toshikazu Hamasaki, Department of Bioengineering & Biomedical Engineering  Dr. Sergio Freire, Department of Bioengineering & Biomedical Engineering Intellectual Property  Provisional patent filed Nanoscale Measurement System

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