1. Statewide IT Conference, Bloomington IN (October 7 th, 2014) The National Center for Genome Analysis Support, IU and You! Carrie Ganote (Bioinformatics Analyst) William K. Barnett, Ph.D. (Director) National Center for Genome Analysis Support

2. Overview Who is NCGAS? What do they do? How does this help me?

3. Started as a 3-year NSF-funded project to support genomics. A collaborative project between our center here at IU, the Pervasive Technology Institute and our partners:

4. Who we are 2.45 FTE Direct Staff 1.Yours Truly – 75% – Bioinformatics Analyst 2.Le-Shin Wu - PhD Computer Scientist 3.Tom Doak – 50% – PhD Genomicist and Biology Liason 4.Bill Barnett – 20% – Director and man with the plan Direct access to the rest of our partner supercomputing centers

5. What we do Provide Cyberinfrastructure to get things done Software support and gateways to lower barriers Consulting for genomics projects

6. Quarry IBM BladeCenter HS21 - General purpose Linux computing environment Big Red 2 Cray XE6/XK7 PetaFLOPS Supercomputer owned by IU Mason HP DL580 - Large memory machine for genomics XSEDE Tier 2 resource Meet the family

7. Short-term project storage on the Data Capacitor 2 High Performance Storage System Storage of up to 50 terabytes of research data on IU's Scientific Data Archive tape storage system. Services for curation and long-term storage of data sets and final results from genome research in the IUScholarWorks Internet 2 backbone for fast data transfer

8. Integrated collection of high-end compute resources for US researchers Distributed network of opportunistically available compute resources for US researchers Meet the family

9. Making IT easier for Biologists Web interface to NCGAS resources Supports many bioinformatics tools Available for both research and instruction. Common Rare Computational Skills LOW HIGH

10. NCGAS Galaxy Model Quarry Gateway Hosting Galaxy.iu.edu The host for each tool is configured individually Quarry Mason Data Capacitor 2 Archive NCGAS establishes tools, hardens them, and moves them into production. Each project can get 50 TB of archive space for raw data and finished products. Individual projects can get duplicate VMs. Policies guarantee that untouched data is removed with time.

11. Consulting Services linux $ Help! home -- bash Bioinformatics should be available to anyone, regardless of their background in informatics or computer related fields. We help with the following: Analysis and interpretation of results Learning to use UNIX Tools of the trade Best practices Experimental design Software installation Troubleshooting Letters of commitment for grant proposals

12. Who can get in on this? NSF Funded Projects and startups –If you have an NSF-Funded genomics project, you are entitled to use our services for free! –If you have a project in mind that is eligible, we may be able to accommodate your project so that you can make your proposal. Members of the IU Community –As a member of IU, you are entitled to use our services for free! –IU pays for our electricity, heating and air conditioning in the Cyberinfrastructure Building located on 10 th and the Bypass, Bloomington IN

13. Who can get in on this? The “Catch” We ask that you acknowledge our grant in any published work that uses our resources. Collaborations and authorship are requested for intellectual contributions.

14. How do I sign up? Email contact is the best way to get in touch with us. We are happy to discuss your project and needs: If you are ready to get your project off the ground, request an allocation at: help@ncgas.org http://ncgas.org/request.php

15. Legal Stuff This material is based upon work supported by the National Science Foundation under Grants No. ABI-1062432 This work was supported in part by the Lilly Endowment, Inc. and the Indiana University Pervasive Technology Institute Any opinions presented here are those of the presenter(s) and do not necessarily represent the opinions of the National Science Foundation or any other funding agencies Except where otherwise noted, contents of this presentation are copyright 2014 by the Trustees of Indiana University. This document is released under the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/). This license includes the following terms: You are free to share – to copy, distribute and transmit the work and to remix – to adapt the work under the following conditions: attribution – you must attribute the work in the manner specified by the author or licensor (but not in any way that suggests that they endorse you or your use of the work). For any reuse or distribution, you must make clear to others the license terms of this work.

16. Fin Questions? Bill Barnett barnettw@iu.edu Tom Doak tdoak@iu.edu Le-Shin Wu lewu@iu.edu Carrie Ganote cganote@iu.edu