1. - Accurate Breast Cancer Detection Estimation - ABCDE - Costantino Giaconia, University of Palermo E-mail: costantino.giaconia@unipa.it Mobile number: +39 320 4376502 -market addressed e-health system manufacturers Public and private health organizations.

2. -R&D and Technical excellence Full exploitation of integrated Silicon Photomultipliers potential Design and realization of portable and low cost multi-sensors embedded system -Research Domain and ASP indication ASP2: Embedded Systems for Healthcare and Wellbeing -Market innovation and impact Novel method with interesting potential low industrial cost Novel Use of Integrated SiPM for e-health application It may potentially change market share among actors

3.  Limitations and disadvantages False-negative rates up to 20% False-positive rates up to 12% Depends on breast tissue density Cannot distinguish benign cancerous Possible harm caused by X-ray exposure Breast Cancer is a leading cause of death for women aged 40-55. In order to early detect this kind of cancer, screening mammography is the most used method.  Advanced Techniques Contrast-Enhanced Mammography Ultrasound or magnetic resonance imaging (MRI) Positron Emission Mammography (PEM) Near Infrared Spectroscopy

4. Consortium status: Well established collaboration between UNIPA and STM Missing capabilities and/or partners Clinical partner e-health Industry stakeholder SME on high tech embedded systems Silicon PhotoMultipliers for Breast Cancer Detection  Advantages of SiPM in NIRS over PIN or APD Higher Gain Lower Cost Lower Bias Voltage Temperature stability Wide dynamic range Ability to have multi-sensor or arrays for Near Infrared Spectroscopy  NIRS Technique Advantages No ionizing radiation (no X-ray) Non-invasive/No contrast agent No breast compression (comfortable) Dense breasts easily imaged Complementary to other breast imaging modalities Easy and inexpensive to implement