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Molecules of Life Chapter 22 Great Idea:
A cell’s major parts are constructed from a few simple molecular building blocks
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Chapter Outline Organic Molecules Proteins: The Workhorses of Life
Carbohydrates Lipids Minerals and Vitamins
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Organic Molecules
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Four Basic Characteristics
Most molecules based on chemistry of carbon Organic molecules Life’s molecules form from few elements H, O, C, N97.5% of body weight Molecules composed of simple building blocks Arranged differently Shape determines behavior Determines ability for bonding
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Chemical Shorthand No H atoms or bonds to H are shown
C atoms are not shown explicitly Shorthand
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Proteins: The Workhorses of Life
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Amino Acids: The Building Blocks of Proteins
Carboxyl group Amino group Carbon atom Side group
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Amino Acids: The Building Blocks of Proteins
Side Group Makes amino acid unique
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Amino Acids cont. Bonding Protein
Two amino acids H bonds with OH Forms H2O Forms peptide bond Polypeptide chain Protein Large molecule Chain of amino acids Only 20 amino acids in living organisms
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The Structure of Proteins
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Proteins as Enzymes Enzymes Specific shape & structure
Facilitates bonding
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Proteins as Enzymes
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How Drugs Work Blocking enzymes Shape of molecules Block active site
Molecules cannot bond Reaction does not take place Shape of molecules Block membrane transport Block neurotransmitters
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Carbohydrates
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Carbohydrates Structure Simplest Monosaccharides Polysaccharide
C, H, O Simplest Sugars CnH2nOn Monosaccharides Polysaccharide Starches Cellulose
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Lipids
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Lipids Lipids Role of lipids Phospholipids Insoluble in water
Cell membranes Store energy Phospholipids Make up cell membrane
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Saturated and Unsaturated Fats
C is fully bonded Basis of cholesterol Unsaturated Monounsaturated Polyunsaturated hydrogenation
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Lipids - molecules with large nonpolar areas soluble in nonpolar solvents:
A triglyceride is a fat or an oil. If the chain contains double bonds the fat is unsaturated.
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Cholesterol - a steroid
An essential component of cell membrane Made from saturated fats
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Like dissolves like. The lipids solubilize nonpolar substances in water.
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Lipid bilayer - a component of the cell membrane
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Cell Membranes Cell membrane Hydrophilic Hydrophobic
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Minerals and Vitamins
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Minerals Minerals Example All chemical elements except C, H, N, O
Calcium 2% of weight
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Vitamins Vitamins Water soluble Fat soluble Function Organic molecules
Must be taken in with food Except vitamin D Water soluble Vitamins B & C Fat soluble Vitamins A, D, E, & K Function Assist enzymes
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