1. Future Of Diagnostic Imaging A Look Into The Next Decade ? (Part 3)

2. 1980’s1990’s2000 - 2010 History of MR Magnets & Base Systems Gradient Systems “The Decade of RF” Fast Spin Echo Echo Planar Imaging Excite The Protons! Fast Easy to Use Robust Anatomical Functional RF Magnet ‘02 ‘07 8-Channel 32-Channel Massively Parallel 1.5T 3.0T Higher Field Strengths MR –More signal, capability, procedures

3. 3.0T Comprehensive Neurosurgery  MR-Guided Intra-Operative Procedures While Maintaining Full OR Functionality.  Multi-Modality Image Guided Techniques.  Support Variety of Surgical Procedures.  State-of-the-Art Patient Transport Design.  Dual use of 3T Magnet:  Diagnostic imaging  MR Guided Surgery

4. 20031998 1.5T 8:00 minutes 1 mm resolution 3T 3.5 minutes 0.16 mm resolution Never been seen before… new applications driving procedure volume

5. Noninvasive / minimally invasive therapy Focused US Tumor Ablation USA Breast Cancer: 180K new cases per year Hysterectomies: 170-300K / year for uterine fibroids 10 Sites globally are in Alpha testing of the technology 400+ patients successfully treated for Uterine Fibroid, Breast Fibroadenoma & Breast Cancer - negligible adverse events Ablation of tumors is monitored in real time using temperature sensitive MR imaging Business Case: >Potential patient population of 100,000+ annually. >Estimated Reimbursement rate: $7K-8K >A clinic can effectively perform 3-4 procedures/day

6. Why Is Digital Mammography Needed? Image Quality Film mammo has 20-35% missed cancers (screening) Film mammo has low positive predictive value Overexposed, underexposed films Film has poor contrast at skin line, chest wall Productivity / Economic Film is expensive to buy, process, handle & store Interventional procedures Only one copy of film – cannot be transmitted Film Screen Mammography Reduces Breast Cancer Mortality by 20-40%, But There is Significant Room for Improvement

7. Review WorkstationAdvanced ApplicationsAcquisition Platform Workflow Connectivity Productivity Quality Control IQ Dose RWS or PACS RIS Interface Storage Cache Improved Detection Softcopy Review Speed During Review CAD Solutions Reduce FP/Biopsy Clinical effectiveness Printer Improved Detection Dataflow Reporting Softcopy Review Speed During Review Connectivity Today’s Digital Solution * CAD Today’s Digital Solution

8.   Computer Aided Diagnosis Tomosynthesis 3D Contrast Mammography Delivered Limitation Interpretation variability Overlapping tissue Lesion 3D features Lesion not x-ray radio-opaque Image quality and QC Solution CAD 3D Contrast U/S FFDM FFDM Advanced Apps Target Mammography’s Key Limitations Delivered FFDM/US Fusion Premium View TACT ® 3D