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Published byAubrey Anderson Modified over 9 years ago
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Gottesman 1991 By Pooja, Jessica and Shohum
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Aims To investigate the risk of developing schizophrenia in different types of genetic relatives of a schizophrenic.
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Procedures Compiled data from 40 family studies from the best Western European studies reported over the past century.
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Findings
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Conclusions Risk for cousins (2%) is only slightly greater than the general population risk. Second-degree relatives have a risk of around 5%, while first- degree relatives have a risk close to 10%. With one schizophrenic parent the risk was 6% with two it rose to 46%. Monozygotic twins had a 48% concordance rate. Dizygotic twins had a 17%. Concordance rates in this study are not 100% which can suggest that the cause of schizophrenia may not be entirely genetic and other factors such as the environment and cognition may also play a role in the risk of an individual developing schizophrenia.
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