1. Genetics of mating incompatibility in fungi BIO341F

2. From: Herskowitz, I. 1988. Microbiol. Rev. 52:536-553.
Yeast cell cycle

3. Yeast cell types and life cycle
From: Herskowitz, I Microbiol. Rev. 52:
Yeast cell types and life cycle

4. Signal transduction pathway from pheromone to transcription
From: Casselton, L. A. & Olesnicky, N. S Molecular genetics of mating recognition in basidiomycete fungi.
Microbiol. Mol. Biol. Rev, 62:55-70.

5. From: Herskowitz, I. 1988. Microbiol. Rev. 52:536-553.

6. Regulatory circuits
From: Herskowitz, I Microbiol. Rev. 52:

7. Regulation of entry into meiosis
From: Herskowitz, I Microbiol. Rev. 52:

8. * * Mating type switching: homothallic versus heterothallic
From: Herskowitz, I Microbiol. Rev. 52: * *

9. From: Herskowitz, I. 1988. Microbiol. Rev. 52:536-553.

10. Switching dependent on HO
MATa
HMRa
HMLa
From: Herskowitz, I Microbiol. Rev. 52:
HMLa
MATa
HMRa
Switching dependent on HO

11. Basidiomycete mating systems
Schizophyllum commune

13. Coprinus cinereus
From: Casselton, L. A. & Olesnicky, N. S Molecular genetics of mating recognition in basidiomycete fungi.
Microbiol. Mol. Biol. Rev, 62:55-70.

14. Unifactorial Incompatibility System- + + A1 + - A2

15. Bifactorial incompatibility system
A1B1
A2B1
A1B2
A2B2
A3B3
A4B3
A3B4
A4B4 - - - + +
A1B1 + -
A2B1
A1B2
A2B2

17. From: Casselton, L. A. & Olesnicky, N. S. 1998
From: Casselton, L. A. & Olesnicky, N. S Molecular genetics of mating recognition in basidiomycete fungi.
Microbiol. Mol. Biol. Rev, 62:55-70.

18. Adaptive potential of dikaryons, diploids, and haploids
Schizophyllum commune
Coprinus cinereus
Travis
Clark
Clark & Anderson Genetics 167:1663
1.5 cm
Anderson and Kohn Dikaryons, diploids, and evolution. In: Sex in Fungi: Molecular Determination and Evolutionary Implications (Eds. Heitman, Kronstad, and Casselton). ASM Press.

19. Mating-type pheromones, receptors and nuclear spacing.
See Schuurs et al FGB 23:
B genes:
-nuclear migration
A Genes:
-nuclear pairing
-coordinate nuclear division
-hook cell formation

20. B genes:
-hook cell fusion
A.H.R. Buller
Ursula Kues
Tim James

21. From Brown & Casselton

23. Appendix: Genome-wide mutation dynamic within a long-lived individual of Armillaria

24. Genetic individuals of Armillaria gallica in a mixed
hardwood forest

25. Mating of two compatible haploid strains
produces a diploid

26. A gene of Armillaria gallica
GME17863_g putative homeodomain 2 protein [Flammulina velutipes] NA MAAY1_SCHCO Mating-type protein A-alpha Y1 OS=Schizophyllum commune PE=2 SV=1 F1CZK4_FLAVE Putative homeodomain 2 protein OS=Flammulina velutipes GN=HD2-1 PE=3 SV=1 IPR001356; Homeobox IPR009057; Homeodomain-like IPR012287; Homeodomain-related IPR017970; Homeobox, conserved site GO: ; DNA binding; Molecular Function GO: ; sequence-specific DNA binding transcription factor activity; Molecular Function GO: ; protein binding; Molecular Function GO: ; nucleus; Cellular Component GO: ; regulation of transcription, DNA-dependent; Biological Process GO: ; transcription regulator activity; Molecular Function GO: ; sequence-specific DNA binding; Molecular Function GO: ; regulation of transcription; Biological Process
GME17864_g homeodomain type 1 mating protein a1-1 [Coprinopsis scobicola] NA MAB11_COPCI Mating-type protein beta1-1 OS=Coprinopsis cinerea PE=3 SV=1 Q9C1N6_COPSC Homeodomain type 1 mating protein a1-1 OS=Coprinopsis scobicola GN=a1-1 PE=3 SV=1 IPR001356; Homeobox IPR008422; Homeobox KN domain IPR009057; Homeodomain-like IPR012287; Homeodomain-related GO: ; DNA binding; Molecular Function GO: ; sequence-specific DNA binding transcription factor activity; Molecular Function GO: ; protein binding; Molecular Function GO: ; nucleus; Cellular Component GO: ; regulation of transcription, DNA-dependent; Biological Process GO: ; sequence-specific DNA binding; Molecular Function GO: ; regulation of transcription; Biological Process