1. Supplementary Figures

2. Data source: Canadian Cancer Statistics 2013

6. APC starts from changepoint year for the following cancer types (stat. sig.): All cancers (males)2003 Prostate (males) 2001 Colorectal (males) 2000 Kidney (males) 2003 Colorectal (females) 2000 Thyroid (females) 2002

7. APC starts from changepoint year for the following cancer types: All cancers (males) 2001 Larynx (males) 2001 Prostate (males) 2001 Non-Hodgkin lymphoma (males) 2001 Non-Hodgkin lymphoma (females) 2000 Breast (females) 2002 Data source: Canadian Cancer Statistics 2013 APC starts from changepoint year for the following cancer types (stat. sig.): All cancers (males)2001 Prostate (males) 2001 Colorectal (males) 2004 All cancers (females) 2002 Ovary 2004

8. Data source: Canadian Cancer Statistics 2013