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Published byUrsula Walsh Modified over 9 years ago
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Conference on Diabetes Types of diabetes mellitus type 1 -- insulin dependent type 2 – insulin independent Experiment with type 1 genetic or environmental w/immuno-supp Assay development radioimmunoassay – insulin concentrations histologic evaluation with Bata cell detection blood glucose measurement blood antibodies measurement
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ISLETS Of LANGERHANS in pancreas
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Acinar cells islet
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ISLETS OF LANGERHANS stained with aldehyde-fuchsin, which selectively stains secretory granules of insulin-secreting Beta cells
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kidney
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Blood sugar concentrations Normal range 80 – 120 mg/dl Diabetic range >120 mg/dl
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ROLES AND SPECIFIC ACTIONS OF ANTIOBODIES IN IMMUNITY COMPLEMENT - MEDIATED LYSIS OPSONIZATION - PROMOTE PHAGOCYTOSIS TOXIN NEUTRALIZATION PREVENTION OF MICROBIAL BINDING TO MUCOSAL SURFACE VIRUS NEUTRALIZATION - INTERFERES WITH CELL PENETRATION
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EFFECTOR T CELLS DELAYED - TYPE HYPERSENSITIVITY T CELLS CYTOTOXIC CELLS DESTROYS TRANSPLANTED ORGANS
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Measure antibodies in blood
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radioimmunoassay for insulin blood concentrations
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