1. CHEM 2412L: Organic Chemistry Laboratory II Dr. Caroline Sheppard

2. Introduction to the course  Roll  Course webpage Course webpage  Short syllabus/syllabus on webpage  Schedule  Lab safety rules and forms Dr. Sheppard CHEM 2412L

3. ChemDraw  You will need this program for your laboratory reports  To download the program, go to http://sitelicense.cambridgesoft.com/sitelicen se.cfm?sid=2560 http://sitelicense.cambridgesoft.com/sitelicen se.cfm?sid=2560  Use Internet Explorer or Firefox  Use your CSU email to log on and follow instructions to download the program  Older versions of ChemDraw are acceptable Dr. Sheppard CHEM 2412L

4.  Check into drawers and kits for Lab 2  One group (2 students) per drawer  Drawer and kit content lists available on the webpage and in the laboratory Lab drawers and kits Dr. Sheppard CHEM 2412L

5.  Laboratory notebooks  Procedure notes  All measurements  All observations  Anything else you will need to write your report  Use Report Sheets as guidelines for observations  Perforated copy gets turned in at the end of the experiment  At the end of second week for two-week labs Some reminders and helpful hints… Dr. Sheppard CHEM 2412L

6.  Significant figures in measurements  Buret volume to 0.00 mL  Melting point to 0.1ºC  Balance to 0.000 g  Melting points  Report as a range and include units  e.g, 101.4 – 102.8 ºC Some reminders and helpful hints… Dr. Sheppard CHEM 2412L

7.  Observations  Should be descriptive  Describe what you observed: color change, formation of precipitate, warming of solution, etc.  Include time it took for change to occur  Clear vs. colorless? Some reminders and helpful hints… Dr. Sheppard CHEM 2412L

8.  When typing pre-labs/reports  Use subscripts in molecular formulas  H 2 SO 4 not H2SO4  Use the degree sign before ºC  Do not capitalize the names of chemicals  Structures should be drawn in ChemDraw  Mechanism curved arrows can be drawn by hand  Calculations may be drawn by hand, but must show all work Some reminders and helpful hints… Dr. Sheppard CHEM 2412L

9. Some reminders and helpful hints… Dr. Sheppard CHEM 2412L

10.  Laboratory Equipment  Ground glass joints in lab kits use vacuum grease  Types of tubing  Clear = water  Thin-walled black or red = gas  Thick-walled black or red = vacuum  Reflux, distillation, etc. Some reminders and helpful hints… Dr. Sheppard CHEM 2412L

11.  Techniques  Use of drying agent  Magnesium sulfate, sodium sulfate  Add in small portions and swirl until the drying agent no longer clumps (floats freely) or until the solution is clear  Use of IR  Instructions by the instrument  You may always ask for help!  Use of GCMS  Must be supervised by an instructor or TA Some reminders and helpful hints… Dr. Sheppard CHEM 2412L