1. Performance and Security of Internet Applications John Buten Manager, Enterprise Industries jbuten@akamai.com

2. © 2008 Akamai Akamai Confidential POWERING A BETTER INTERNET Who is Akamai? Leader in powering rich media, dynamic transactions and enterprise applications online Proven to speed dynamic Web sites and applications by up to 500% $860MM in Revenue 2009 NASDAQ: AKAM 3,100+ Customers 1,400+ Employees

3. © 2008 Akamai Evolution of Health Information Post Fax EDI Internet

4. © 2008 Akamai Imperatives of Health 2.0 1.Performance Matters 2.Size Matters 3.Security Matters 4.Location Matters Akamai Confidential POWERING A BETTER INTERNET

5. © 2008 Akamai 1. Performance Matters Akamai Confidential POWERING A BETTER INTERNET 8 Seconds4 Seconds 2 Seconds 1999 2006 2009 0246 8 10 Response Time (seconds) Consumer Expectation for Page Load Source: Jupiter Research Source: Forrester Research Over 50% of consumers expect pages to load in 2 seconds or less North American consumers

6. © 2008 Akamai 1. Performance Matters Akamai Confidential POWERING A BETTER INTERNET 0300 Page Response Time (Seconds) Page Weight (KB) 50100150200250 0 2 4 6 8 10 12 14 16 18 20 2.4 seconds/100KB Sites are getting heavier and slower, not lighter and faster Source: Akamai - global average page response of

7. © 2008 Akamai 2. Size Matters Akamai Confidential Web sites are critical point of communication in moment of truth

8. © 2008 Akamai 2. Size Matters Akamai Confidential POWERING A BETTER INTERNET Web sites are critical point of communication in moment of truth

9. © 2008 Akamai 3. Security Matters Healthcare and Pharmaceutical lead other industries with a poor 50% Source: White Hat Security, 2009 Social Networking High Tech Financial Services InsuranceRetailPharmaTelecommHealth

10. © 2008 Akamai 3. Security Matters 130 million accounts compromised $100 million in fines to card issuers 200-500,000 records compromised Forced to notify members 29,000 employee records compromised 15,000 patient records compromised $200,000 in fines Data theft is real as are the consequences

11. © 2008 Akamai 4. Location Matters Akamai Confidential POWERING A BETTER INTERNET Healthcare and Pharmaceutical lead other industries with a poor 50%

12. © 2008 Akamai 4. Location Matters POWERING A BETTER INTERNET Clinical research is a global endeavor Countries with Rave Sites Medidata Offices Outsourced Locations Data Center North America 76% +6%  South America 1% +165%  Europe 18% +25%  Asia 4% +93%  R&D Spend Analysis (PhRMA Members, 07) % of Worldwide Total R&D Spend % Change in Spend 06-07

13. © 2008 Akamai Akamai’s Vantage Point The world’s largest on-demand, distributed computing platform delivers all forms of Web content and applications for over 2,800 customers and 25,000 domains Resulting in traffic of: 500 billion hits / day 8+ million hits per second 100+ million streams / day 1,000,000+ concurrent streams 800+ Gbps The Akamai EdgePlatform: 60,000+ Servers 3,000+ Locations 70 Countries 1,000+ Networks 750+ Cities

14. Powering a Better Internet © 2009 Akamai Making the Internet Reliable Akamai’s Edge Platform and optimization technologies make the Internet a reliable and high-performance place to do business End User Application Origin Route Optimization Protocol Optimization Application Optimization

15. Powering a Better Internet © 2009 Akamai 0300 Page Response Time (Seconds) Page Weight (KB) 50100150200250 0 2 4 6 8 10 12 14 16 18 20 Without Akamai With Akamai 2.4 seconds/100KB 0.7 seconds/100KB Akamai enables richer Web experiences

16. © 2008 Akamai Akamai Flattens the Globe Akamai Confidential POWERING A BETTER INTERNET Online Transaction Speed (seconds)

17. © 2008 Akamai Akamai Inherent Security Protecting Applications in the Cloud Akamai’s 60,000+ servers act as a distributed firewall Resources for outclassing any DDOS or DNS attack Lock down your application to unknown traffic

18. Questions / Réponses John Buten Manager, Enterprise Industries jbuten@akamai.com