C h a p t e r 10 Muscle Tissue PowerPoint® Lecture Slides prepared by Jason LaPres Lone Star College - North Harris Copyright © 2009 Pearson Education,

C h a p t e r 10 Muscle Tissue PowerPoint® Lecture Slides prepared by Jason LaPres Lone Star College - North Harris Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

An Introduction to Muscle Tissue
A primary tissue type, divided into Skeletal muscle Cardiac muscle Smooth muscle Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

An Introduction to Muscle Tissue
Skeletal Muscles Are attached to the skeletal system Allow us to move The muscular system Includes only skeletal muscles Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Functions of Skeletal Muscles
Produce skeletal movement Maintain body position Support soft tissues Guard openings Maintain body temperature Store nutrient reserves Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Skeletal Muscle Structures
Muscle tissue (muscle cells or fibers) Connective tissues Nerves Blood vessels Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Organization of Connective Tissues Muscles have three layers of connective tissues Epimysium: exterior collagen layer connected to deep fascia Separates muscle from surrounding tissues Perimysium: surrounds muscle fiber bundles (fascicles) contains blood vessel and nerve supply to fascicles Endomysium: surrounds individual muscle cells (muscle fibers) contains capillaries and nerve fibers contacting muscle cells contains myosatellite cells (stem cells) that repair damage Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Organization of Connective Tissues Muscle attachments Endomysium, perimysium, and epimysium come together: at ends of muscles to form connective tissue attachment to bone matrix i.e., tendon (bundle) or aponeurosis (sheet) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Nerves Skeletal muscles are voluntary muscles, controlled by nerves of the central nervous system (brain and spinal cord) Blood Vessels Muscles have extensive vascular systems that Supply large amounts of oxygen Supply nutrients Carry away wastes Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Skeletal Muscle Fibers
Are very long Develop through fusion of mesodermal cells (myoblasts) Become very large Contain hundreds of nuclei Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Internal Organization of Muscle Fibers The sarcolemma The cell membrane of a muscle fiber (cell) Surrounds the sarcoplasm (cytoplasm of muscle fiber) A change in transmembrane potential begins contractions Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Internal Organization of Muscle Fibers Transverse tubules (T tubules) Transmit action potential through cell Allow entire muscle fiber to contract simultaneously Have same properties as sarcolemma Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Internal Organization of Muscle Fibers Myofibrils Lengthwise subdivisions within muscle fiber Made up of bundles of protein filaments (myofilaments) Myofilaments are responsible for muscle contraction Types of myofilaments: thin filaments: made of the protein actin thick filaments: made of the protein myosin Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Internal Organization of Muscle Fibers Sarcoplasmic reticulum (SR) A membranous structure surrounding each myofibril Helps transmit action potential to myofibril Similar in structure to smooth endoplasmic reticulum Forms chambers (terminal cisternae) attached to T tubules Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Internal Organization of Muscle Fibers Triad Is formed by one T tubule and two terminal cisternae Cisternae: concentrate Ca2+ (via ion pumps) release Ca2+ into sarcomeres to begin muscle contraction Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Internal Organization of Muscle Fibers Sarcomeres The contractile units of muscle Structural units of myofibrils Form visible patterns within myofibrils Muscle striations A striped or striated pattern within myofibrils: alternating dark, thick filaments (A bands) and light, thin filaments (I bands) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Internal Organization of Muscle Fibers Sarcomeres M Lines and Z Lines: M line: the center of the A band at midline of sarcomere Z lines: the centers of the I bands at two ends of sarcomere Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Internal Organization of Muscle Fibers Sarcomeres Zone of overlap: the densest, darkest area on a light micrograph where thick and thin filaments overlap The H Band: the area around the M line has thick filaments but no thin filaments Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Internal Organization of Muscle Fibers Sarcomeres Titin: are strands of protein reach from tips of thick filaments to the Z line stabilize the filaments Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Sarcomere Function Transverse tubules encircle the sarcomere near zones of overlap Ca2+ released by SR causes thin and thick filaments to interact Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Muscle Contraction Is caused by interactions of thick and thin filaments Structures of protein molecules determine interactions Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Four Thin Filament Proteins F-actin (Filamentous actin) Is two twisted rows of globular G-actin The active sites on G-actin strands bind to myosin Nebulin Holds F-actin strands together Tropomyosin Is a double strand Prevents actin–myosin interaction Troponin A globular protein Binds tropomyosin to G-actin Controlled by Ca2+ Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Initiating Contraction Ca2+ binds to receptor on troponin molecule Troponin–tropomyosin complex changes Exposes active site of F-actin Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Thick Filaments Contain twisted myosin subunits Contain titin strands that recoil after stretching The mysosin molecule Tail: binds to other myosin molecules Head: made of two globular protein subunits reaches the nearest thin filament Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Myosin Action During contraction, myosin heads Interact with actin filaments, forming cross-bridges Pivot, producing motion Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Skeletal Muscle Contraction Sliding filament theory Thin filaments of sarcomere slide toward M line, alongside thick filaments The width of A zone stays the same Z lines move closer together Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Skeletal Muscle Contraction The process of contraction Neural stimulation of sarcolemma: causes excitation–contraction coupling Cisternae of SR release Ca2+: which triggers interaction of thick and thin filaments consuming ATP and producing tension Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

The Neuromuscular Junction
Is the location of neural stimulation Action potential (electrical signal) Travels along nerve axon Ends at synaptic terminal Synaptic terminal: releases neurotransmitter (acetylcholine or ACh) into the synaptic cleft (gap between synaptic terminal and motor end plate) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

The Neurotransmitter Acetylcholine or ACh Travels across the synaptic cleft Binds to membrane receptors on sarcolemma (motor end plate) Causes sodium–ion rush into sarcoplasm Is quickly broken down by enzyme (acetylcholinesterase or AChE) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Action Potential Generated by increase in sodium ions in sarcolemma Travels along the T tubules Leads to excitation–contraction coupling Excitation–contraction coupling: action potential reaches a triad: releasing Ca2+ triggering contraction requires myosin heads to be in “cocked” position: loaded by ATP energy Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

The Contraction Cycle Five Steps of the Contraction Cycle
Exposure of active sites Formation of cross-bridges Pivoting of myosin heads Detachment of cross-bridges Reactivation of myosin Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

The Contraction Cycle Figure 10–12 The Contraction Cycle.
Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

The Contraction Cycle [INSERT FIG. 10.12, step 1]
Figure 10–12 The Contraction Cycle. Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

The Contraction Cycle Figure 10–12 The Contraction Cycle.

The Contraction Cycle Fiber Shortening Contraction Duration
As sarcomeres shorten, muscle pulls together, producing tension Contraction Duration Depends on Duration of neural stimulus Number of free calcium ions in sarcoplasm Availability of ATP Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

The Contraction Cycle Figure 10–13 Shortening during a Contraction.

The Contraction Cycle Relaxation Rigor Mortis Ca2+ concentrations fall
Ca2+ detaches from troponin Active sites are re-covered by tropomyosin Sarcomeres remain contracted Rigor Mortis A fixed muscular contraction after death Caused when Ion pumps cease to function; ran out of ATP Calcium builds up in the sarcoplasm Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

The Contraction Cycle Skeletal muscle fibers shorten as thin filaments slide between thick filaments Free Ca2+ in the sarcoplasm triggers contraction SR releases Ca2+ when a motor neuron stimulates the muscle fiber Contraction is an active process Relaxation and return to resting length are passive Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production The all–or–none principle
As a whole, a muscle fiber is either contracted or relaxed Tension of a Single Muscle Fiber Depends on The number of pivoting cross-bridges The fiber’s resting length at the time of stimulation The frequency of stimulation Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production Tension of a Single Muscle Fiber
Length–tension relationship Number of pivoting cross-bridges depends on: amount of overlap between thick and thin fibers Optimum overlap produces greatest amount of tension: too much or too little reduces efficiency Normal resting sarcomere length: is 75% to 130% of optimal length Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production Tension of a Single Muscle Fiber
Frequency of stimulation A single neural stimulation produces: a single contraction or twitch which lasts about 7–100 msec. Sustained muscular contractions: require many repeated stimuli Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production Three Phases of Twitch
Latent period before contraction The action potential moves through sarcolemma Causing Ca2+ release Contraction phase Calcium ions bind Tension builds to peak Relaxation phase Ca2+ levels fall Active sites are covered Tension falls to resting levels Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production Treppe A stair-step increase in twitch tension
Repeated stimulations immediately after relaxation phase Stimulus frequency <50/second Causes a series of contractions with increasing tension Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production Tension of a Single Muscle Fiber Wave summation
Increasing tension or summation of twitches Repeated stimulations before the end of relaxation phase: stimulus frequency >50/second Causes increasing tension or summation of twitches Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production Tension of a Single Muscle Fiber Incomplete tetanus
Twitches reach maximum tension If rapid stimulation continues and muscle is not allowed to relax, twitches reach maximum level of tension Complete Tetanus If stimulation frequency is high enough, muscle never begins to relax, and is in continuous contraction Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production Figure 10–16 Effects of Repeated Stimulations.

Tension Production Tension Produced by Whole Skeletal Muscles
Depends on Internal tension produced by muscle fibers External tension exerted by muscle fibers on elastic extracellular fibers Total number of muscle fibers stimulated Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Motor units in a skeletal muscle Contain hundreds of muscle fibers That contract at the same time Controlled by a single motor neuron Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Recruitment (multiple motor unit summation) In a whole muscle or group of muscles, smooth motion and increasing tension are produced by slowly increasing the size or number of motor units stimulated Maximum tension Achieved when all motor units reach tetanus Can be sustained only a very short time Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Sustained tension Less than maximum tension Allows motor units rest in rotation Muscle tone The normal tension and firmness of a muscle at rest Muscle units actively maintain body position, without motion Increasing muscle tone increases metabolic energy used, even at rest Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production Two Types of Skeletal Muscle Tension
Isotonic contraction Isometric contraction Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Isotonic Contraction Skeletal muscle changes length: resulting in motion If muscle tension > load (resistance): muscle shortens (concentric contraction) If muscle tension < load (resistance): muscle lengthens (eccentric contraction) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Isometric contraction Skeletal muscle develops tension, but is prevented from changing length Note: iso- = same, metric = measure Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production Resistance and Speed of Contraction
Are inversely related The heavier the load (resistance) on a muscle The longer it takes for shortening to begin And the less the muscle will shorten Muscle Relaxation After contraction, a muscle fiber returns to resting length by Elastic forces Opposing muscle contractions Gravity Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production Figure 10–19 Load and Speed of Contraction.

Tension Production Elastic Forces Opposing Muscle Contractions
The pull of elastic elements (tendons and ligaments) Expands the sarcomeres to resting length Opposing Muscle Contractions Reverse the direction of the original motion Are the work of opposing skeletal muscle pairs Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Tension Production Gravity
Can take the place of opposing muscle contraction to return a muscle to its resting state Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

ATP and Muscle Contraction
Sustained muscle contraction uses a lot of ATP energy Muscles store enough energy to start contraction Muscle fibers must manufacture more ATP as needed Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

ATP and CP Reserves Adenosine triphosphate (ATP) The active energy molecule Creatine phosphate (CP) The storage molecule for excess ATP energy in resting muscle Energy recharges ADP to ATP Using the enzyme creatine phosphokinase (CPK or CK) When CP is used up, other mechanisms generate ATP Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

ATP Generation Cells produce ATP in two ways Aerobic metabolism of fatty acids in the mitochondria Anaerobic glycolysis in the cytoplasm Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

ATP Generation Aerobic metabolism Is the primary energy source of resting muscles Breaks down fatty acids Produces 34 ATP molecules per glucose molecule Anaerobic glycolysis Is the primary energy source for peak muscular activity Produces two ATP molecules per molecule of glucose Breaks down glucose from glycogen stored in skeletal muscles Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Energy Use and Muscle Activity At peak exertion Muscles lack oxygen to support mitochondria Muscles rely on glycolysis for ATP Pyruvic acid builds up, is converted to lactic acid Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Muscle Fatigue When muscles can no longer perform a required activity, they are fatigued Results of Muscle Fatigue Depletion of metabolic reserves Damage to sarcolemma and sarcoplasmic reticulum Low pH (lactic acid) Muscle exhaustion and pain Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

The Recovery Period The time required after exertion for muscles to return to normal Oxygen becomes available Mitochondrial activity resumes Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

The Cori Cycle The removal and recycling of lactic acid by the liver Liver converts lactic acid to pyruvic acid Glucose is released to recharge muscle glycogen reserves Oxygen Debt After exercise or other exertion The body needs more oxygen than usual to normalize metabolic activities Resulting in heavy breathing Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Skeletal muscles at rest metabolize fatty acids and store glycogen During light activity, muscles generate ATP through anaerobic breakdown of carbohydrates, lipids, or amino acids At peak activity, energy is provided by anaerobic reactions that generate lactic acid as a byproduct Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Heat Production and Loss Active muscles produce heat Up to 70% of muscle energy can be lost as heat, raising body temperature Hormones and Muscle Metabolism Growth hormone Testosterone Thyroid hormones Epinephrine Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Muscle Performance Power The maximum amount of tension produced Endurance The amount of time an activity can be sustained Power and endurance depend on The types of muscle fibers Physical conditioning Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Muscle Fiber Types Three Types of Skeletal Muscle Fibers Fast fibers
Contract very quickly Have large diameter, large glycogen reserves, few mitochondria Have strong contractions, fatigue quickly Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Muscle Fiber Types Three Types of Skeletal Muscle Fibers Slow fibers
Are slow to contract, slow to fatigue Have small diameter, more mitochondria Have high oxygen supply Contain myoglobin (red pigment, binds oxygen) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Muscle Fiber Types Three Types of Skeletal Muscle Fibers
Intermediate fibers Are mid-sized Have low myoglobin Have more capillaries than fast fibers, slower to fatigue Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Muscle Fiber Types Figure 10–21 Fast versus Slow Fibers.

Muscle Fiber Types Muscles and Fiber Types White muscle Red muscle
Mostly fast fibers Pale (e.g., chicken breast) Red muscle Mostly slow fibers Dark (e.g., chicken legs) Most human muscles Mixed fibers Pink Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Muscle Fiber Types Muscle Hypertrophy Muscle Atrophy
Muscle growth from heavy training Increases diameter of muscle fibers Increases number of myofibrils Increases mitochondria, glycogen reserves Muscle Atrophy Lack of muscle activity Reduces muscle size, tone, and power Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Muscle Fiber Types Physical Conditioning
Improves both power and endurance Anaerobic activities (e.g., 50-meter dash, weightlifting): use fast fibers fatigue quickly with strenuous activity Improved by: frequent, brief, intensive workouts hypertrophy Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Muscle Fiber Types Physical Conditioning
Improves both power and endurance Aerobic activities (prolonged activity): supported by mitochondria require oxygen and nutrients Improved by: repetitive training (neural responses) cardiovascular training Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Muscle Fiber Types What you don’t use, you lose
Muscle tone indicates base activity in motor units of skeletal muscles Muscles become flaccid when inactive for days or weeks Muscle fibers break down proteins, become smaller and weaker With prolonged inactivity, fibrous tissue may replace muscle fibers Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Cardiac Muscle Tissue Seven Characteristics of Cardiocytes
Unlike skeletal muscle, cardiac muscle cells (cardiocytes) Are small Have a single nucleus Have short, wide T tubules Have no triads Have SR with no terminal cisternae Are aerobic (high in myoglobin, mitochondria) Have intercalated discs Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Cardiac Muscle Tissue Intercalated Discs
Are specialized contact points between cardiocytes Join cell membranes of adjacent cardiocytes (gap junctions, desmosomes) Functions of intercalated discs Maintain structure Enhance molecular and electrical connections Conduct action potentials Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Cardiac Muscle Tissue Figure 10–22 Cardiac Muscle Tissue.

Cardiac Muscle Tissue Figure 10–22a Cardiac Muscle Tissue.

Cardiac Muscle Tissue Figure 10–22c Cardiac Muscle Tissue.

Cardiac Muscle Tissue Intercalated Discs Coordination of cardiocytes
Because intercalated discs link heart cells mechanically, chemically, and electrically, the heart functions like a single, fused mass of cells Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Cardiac Muscle Tissue Four Functions of Cardiac Tissue Automaticity
Contraction without neural stimulation Controlled by pacemaker cells Variable contraction tension Controlled by nervous system Extended contraction time Ten times as long as skeletal muscle Prevention of wave summation and tetanic contractions by cell membranes Long refractory period Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Smooth Muscle Tissue Smooth Muscle in Body Systems
Forms around other tissues In blood vessels Regulates blood pressure and flow In reproductive and glandular systems Produces movements In digestive and urinary systems Forms sphincters Produces contractions In integumentary system Arrector pili muscles cause “goose bumps” Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Smooth Muscle Tissue Structure of Smooth Muscle Nonstriated tissue
Different internal organization of actin and myosin Different functional characteristics Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Smooth Muscle Tissue Figure 10–23a Smooth Muscle Tissue.

Smooth Muscle Tissue Figure 10–23b Smooth Muscle Tissue.

Smooth Muscle Tissue Eight Characteristics of Smooth Muscle Cells
Long, slender, and spindle shaped Have a single, central nucleus Have no T tubules, myofibrils, or sarcomeres Have no tendons or aponeuroses Have scattered myosin fibers Myosin fibers have more heads per thick filament Have thin filaments attached to dense bodies Dense bodies transmit contractions from cell to cell Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Smooth Muscle Tissue Functional Characteristics of Smooth Muscle
Excitation–contraction coupling Length–tension relationships Control of contractions Smooth muscle tone Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Excitation–contraction coupling Free Ca2+ in cytoplasm triggers contraction Ca2+ binds with calmodulin: in the sarcoplasm activates myosin light–chain kinase Enzyme breaks down ATP, initiates contraction Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Length–Tension Relationships Thick and thin filaments are scattered Resting length not related to tension development Functions over a wide range of lengths (plasticity) Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Control of contractions Multiunit smooth muscle cells: connected to motor neurons Visceral smooth muscle cells: not connected to motor neurons rhythmic cycles of activity controlled by pacesetter cells Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings

Comparing Muscle Tissues

C h a p t e r 10 Muscle Tissue PowerPoint® Lecture Slides prepared by Jason LaPres Lone Star College - North Harris Copyright © 2009 Pearson Education,

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C h a p t e r 10 Muscle Tissue PowerPoint® Lecture Slides prepared by Jason LaPres Lone Star College - North Harris Copyright © 2009 Pearson Education,

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Presentation on theme: "C h a p t e r 10 Muscle Tissue PowerPoint® Lecture Slides prepared by Jason LaPres Lone Star College - North Harris Copyright © 2009 Pearson Education,"— Presentation transcript:

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