1. Regenerativna medicina- priložnost za podjetja? Miomir Knežević Nacionalni inštitut za biologijo www.nib.si miomir.knezevic@nib.si

2. Uporabljeni material: Stem cells and the innovation process –Dr Paul Martin –Institute for the Study of Genetics, Biorisks and Society (IGBiS) University of Nottingham, UK Global commercialisation of UK stem cell research Nicola Perrin: N.M.R.Perrin.04@cantab.net N.M.R.Perrin.04@cantab.net Ian Bunker: Ian.bunker@uktradeinvest.gov.uk Ian.bunker@uktradeinvest.gov.uk The Role of Technology Foresight in Anticipating Global Technology Trend, Terutaka KUWAHARA, NISTEP

3. Ocene poslovnih priložnosti

4. Embrionalne matične celice Tkivno inženirstvo

5. Ne moreš graditi ugleda na tistem, kar šele nameravaš narediti Henry Ford

6. Uporaba nanotehnologije

7. Zakasnitveni čas od tehnološke realizacije do uporabe

8. 2005- 20152015-2025 Information and communications Electronics Life sciences Information and communications Electronics Space, marine and earth science Environment Energy and resources Manufacturing Nanotechnology and material Agriculture, forestry, fisheries and food Social infrastructure Industrial infrastructure Health, medical care and welfare Science and technology for society *1 Respondents chose at most three fields to cooperate. *2 Black arrow indicates that 30% to 50% of respondents. *3 Red arrow indicates that more than 50% of respondents. Nanotechnology and material Nanotechnology and material Multidisciplinarno okolje – Vede o življenju postajajo center

9. Basic research in drug development Regenerative medical science Technology for measuring biological substances Environmental and ecological biology Controlling higher-order biological functions Higher-order brain functions Brain generation and growth Bioinfomatics Basic research for new medical technologies Nanobiology Understanding and treating brain conditions Index povečanja znanja Socialno-ekonomski pomen Po 2015 Pred 2015 Sprememba vpliva “Ved o življenju”

10. Predvideni čas realizacije tehnologij – Vede o življenju Čas uporabe v praksi Bioinformatics Controlling higher-order biological functions Technology for measuring biological substances Understanding and treating brain conditions Basic research for new medical technologies Basic research in drug development Environmental and ecological biology Nanobiology Regenerative medical science Čas tehnološke realizacije

11. Najpomembnejše tehnologije na področju Ved o življenju “Top 10” TopicArea Year Effective technology to prevent cancer metastasis.Basic research for new medical technologies 2020 / 2030 Technology for immediate, complete control of allergies based on elucidation of the immunoregulatory mechanisms and environmental factors that lead to hay fever, atopic dermatitis, and other allergies. Basic research for new medical technologies 2015 / 2027 Treatment for preventing the progression of Alzheimer's disease.Understanding and treating brain conditions 2019 / 2030 Elucidation of the etiology of manic-dpressive psychosis at the molecular level. Understanding and treating brain conditions 2020 / - Technology to detect a cancerous tissue of the diameter smaller than 1 mm presenting anywhere in the body. Technology for measuring biological substances 2014 / 2023 Elucidation of the etiology of schizophrenia at the molecular level.Understanding and treating brain conditions 2022 / - Technologies for drug development to predict bioactivities of proteins such as interactions between protein and protein, between proteins and DNA or RNA, and between proteins and synthetic compounds from their higher order structure. Basic research in drug development 2015 / 2026 Mass production technology for fuels and bioplastics utilizing plants and microorganisms. Environmental and ecological biology 2014 / 2024 Technology to manipulate stem cell differentiation and growth for induction of functional cells to use for therapy. Regenerative medical science 2016 / 2029 Effective cancer prevention measures can be implemented by clarifying the relationships among multiple environmental risk factors associated with cancer. Basic research for new medical technologies 2020 / 2030 : Nove medicinske tehnologije in zdravila : Študij možganov : Regenerativna medicina

12. Regenerativna medicina Tehnološka pot Izdelava umetnih organov Razvoj osnivne tehnologije

13. Time (years) Value 5 10 15 20 Training Cell therapies Research tools Clinical trials Manufacturing Drug screening Cell banking Growth factors Toxicity testing Therapeutics Research applications Enabling technologies Timescale for commercial opportunities

14. Stopnje: Infrastruktura : Deležniki: Financiranje: ???? Basic Research Applied Development Clinical Therapies Universities, Research Institutes Biotech SMEs Pharma Clinicians Government / regulatory agencies Commercial funding VC, pharma Research Councils Charities Manufacturing Funding Gap Translation of stem cell research into commercial products

15. Noben uspeh ni dokončen, nobena napaka ni nepopravljiva: šteje le pogum, da nadaljuješ. Winston Churchill