1. Candis M. Morello, PharmD, CDE Research Interests Exploring clinical outcomes in diabetes patients Director, Diabetes Intense Medical Management Clinic, VASDHS Research Team with Jan Hirsch DIMM Clinic Managers Team Ginger Lo, Class of 2018 Mandy Leung, Class of 2018 Jennifer Vu, Class of 2017 Carmen Truong, Class of 2017 Clinical and Long Term Outcomes Andrea Bechthold, Class of 2014 John Khoan, Class of 2016 Patient Satisfaction Outcomes Sandy Chong, Class of 2014 Medication Adherence Outcomes Crystal Zhou, Class of 2015 Pharmacoeconomic Outcomes David Ha, Class of 2012 Christine Cadiz, Class of 2012 Mark Bounthavong, PharmD Andrew Zimmerman, Class of 2015 Medication & Comorbid Complexity John Khoan, Class of 2016 Taylor Rotunno, Class of 2016

2. Clinical Care: Finding the Best Combo with the Patient Stomach: GLP-1 analogs and amylin analog (slows gastric emptying) Brain: GLP-1 analogs, amylin analog (satiety) Pancreas/Beta cells: SFU, Glinides (insulin secretion) GLP-1 analogs, DPP-4 Inh (glucose- dependent insulin secretion) Pancreas/Alpha cells: GLP-1 analogs, amylin analog, DPP-4 Inh (  postprandial glucagon secretion) Gut: GLP-1 agonist, analog Mouth: GLP-1 analogs, amylin analog (reduced caloric intake) Muscles and tissues: TZD, Metformin (insulin sensitivity), Insulin (peripheral glucose uptake) Gut: AGI /BAS (delays CHO breakdown/absorption) Liver: Metformin, Insulin, GLP-1 analogs, amylin analog, DPP-4 Inh (↓ Hepatic glucose output)output) Image developed from images at: www.topnews.in/healthcare/node?page=12, www.jamesgillespiesps.ik.org, www.beyondbiology.org/beyondbiology.org/index on 6/18/10.Revised 6/9/14 CMMorellowww.topnews.in/healthcare/node?page=12www.jamesgillespiesps.ik.org www.beyondbiology.org/beyondbiology.org/index on 6/18/10.Revised Kidneys: SGLT-2 inh (increases glucose urinary output)

3. MEDICATION ADHERENCE COOKING GROCERIES LIVING SITUATION CULTURAL BELIEFS & PREFERENCES PHYSICAL ACTIVITY ACCESS TO CARE READINESS TO CHANGE USE OF TOBACCO, EtOH, ILLICIT DRUGS LEGAL ISSUES QUALITY & QUANITITY OF FOOD WEIGHT GLYCEMIC CONTROL HYPOGLYCEMIA NOCTURIA, BLURRY VISION, LOW ENERGY ELECTROLYES SODIUM INTAKE RENAL STATUS NEPHROPATHY MICROALBUMINERIA RETINOPATHY FOOT CARE PVD VISION CHANGES AMPUTATIONS FUNGAL INFECTIONS BACTERIAL INFECTIONS BLINDNESS MOTIVATING FACTORS FINANCES PERSON WITH DIABETES CLINICAL SOCIOECONOMIC AND BEHAVIORAL COMPLICATIONS MTM Spider Web © Adapted from Morello CM, Hirsch J, Lee KC. Navigating the complexity of patients through an innovative tool: The MTM Spider Web. JAPhA.2013; 53(5):530–538. Use of the MTM Spider Web © is protected by U.S. copyright laws. Permission for use is required by primary author at andismorello@ucsd.edu. DPN MEDICATION MONITORING, ADRS MEDICATION COMPLEXITY Individualized Clinical Care

4. Proposed Collaborations with SSPPS Faculty General Diabetes treatments Diabetes prevention Inflammatory impact on diabetes Medication therapy management Medication complexity Pharmacoeconomic impact Geriatrics Associated Conditions Cardiovascular Lipids Hypertension Neuropathy Retinopathy Nephropathy Wound healing Depression Hypothyroidism