1. © NuAge Vision 2014 Email: admin@nuage-vision.comadmin@nuage-vision.com Webwww.nuage-vision.com Tel:+44 (0) 7803 122 583 +44 (0) 7553 040 928 Creating and Running Companies Bruce Savage BioQuest Consulting  What do I do?  Work with scientific founder/university to write business plan, raise investment and run the business on part time basis  I am currently on start up no 8  Have raised £14m

2. © NuAge Vision 2014 Email: admin@nuage-vision.comadmin@nuage-vision.com Webwww.nuage-vision.com Tel:+44 (0) 7803 122 583 +44 (0) 7553 040 928 Critical issues in running a successful company  Credible, realistic business plan  Strong focus on how co will make money and how it will give investors a good return  Raising adequate investment  Experienced management  Strong, clean IP with a plan to increase patent portfolio

3. © NuAge Vision 2014 Email: admin@nuage-vision.comadmin@nuage-vision.com Webwww.nuage-vision.com Tel:+44 (0) 7803 122 583 +44 (0) 7553 040 928 Comments on IP  Investors invest in your patents – your major asset  BUT looking for quality  patents in application do not have same value as granted patents  A good examination report can help with investment  Road to obtaining a granted patent can be long and expensive and risky  A freedom to operate search can help investors confidence

4. © NuAge Vision 2014 Email: admin@nuage-vision.comadmin@nuage-vision.com Webwww.nuage-vision.com Tel:+44 (0) 7803 122 583 +44 (0) 7553 040 928 How to build real value  Substantiate claims  Reduce to practice  Build a portfolio around core patent  Demonstrate real commercial value of IP by showing strong growth in sales of patent protected products

5. © NuAge Vision 2014 Email: admin@nuage-vision.comadmin@nuage-vision.com Webwww.nuage-vision.com Tel:+44 (0) 7803 122 583 +44 (0) 7553 040 928 Cytocell Molecular diagnostics company detection of genetic diseases  Sold products worldwide through distributors  98% sales outside UK  Core technology – through collaboration and sought licensing deals  IP problems principally in US  In licensed main product from Univ Oxford

6. © NuAge Vision 2014 Email: admin@nuage-vision.comadmin@nuage-vision.com Webwww.nuage-vision.com Tel:+44 (0) 7803 122 583 +44 (0) 7553 040 928 BioAnalab  Spin out from Univ Oxford – service company with pharma companies as customers  Strong growth in sales through  Web site  Conferences  Business development exec.  Know-how (SOP’s) but not patents licensed from university  Great deal of know-how in complex field

7. © NuAge Vision 2014 Email: admin@nuage-vision.comadmin@nuage-vision.com Webwww.nuage-vision.com Tel:+44 (0) 7803 122 583 +44 (0) 7553 040 928 CMP Therapeutics  Novel treatment for allergies based on natural product  IP assigned (not licensed) from Medical Research Council  Commercialisation through license deals once efficacy shown in clinical trials  IP issues in US but solved by inventor meeting USPO

8. © NuAge Vision 2014 Email: admin@nuage-vision.comadmin@nuage-vision.com Webwww.nuage-vision.com Tel:+44 (0) 7803 122 583 +44 (0) 7553 040 928 GFC Diagnostics  Test kits to detect smoking – insurance industry and hospital customers  Sales generated mainly through web site - worldwide and some personal selling  Initial patent on device lapsed but new patent filed on new chemistry, granted in US with no issues!!  Patent filing fees big cost  Strong growth in sales

9. © NuAge Vision 2014 Email: admin@nuage-vision.comadmin@nuage-vision.com Webwww.nuage-vision.com Tel:+44 (0) 7803 122 583 +44 (0) 7553 040 928 Summary  A granted patent really helps raise investment but there are other important considerations  Business plan must have a focus on a realistic commercialisation plan with a credible exit strategy.  Good management with experienced sales and marketing team  Good luck – especially with US patent office!