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Published byMerilyn Barnett Modified over 9 years ago
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Population Genetic Hardy-Wienberg Law Genetic drift Inbreeding Genetic Bottleneck Outbreeding Founder event Effective population size Gene flow
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Population Genetics Genotype, phenotype locus, genotype frequency, allele frequency
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Determining the genotype for an enzyme in a fish.
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IDHP (isocitrate dehydrogenase) from a grasshopper Individuals 1 2 3... AA aa Aa
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Genotype and Phenotype Genotypes AA, aa (Homozygous), Aa (Heterozygous) Phenotype trait X = AA and Aa, trait Y = aa Alleles A and a If p = proportion of allele A and if q = proportion of allele a Then p+q = 1 Knowing p and q the Hardy-Wienberg Equilibrium gives the expected frequency of the three genotypes as: (p+q) 2 = p 2 +2pq + q 2 = 1 AA = p 2, aa = q 2 and Aa = 2pq
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Hardy-Wienberg Equilibrium Assumptions Population size is very large Random mating is occurring No mutation is taking place No immigration (geneflow) No selection is occurring
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Genetic drift
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Inbreeding A alleles common by descent
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Effective population size Founder effect Genetic bottleneck Outbreeding depression Gene flow
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