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Population Genetic Hardy-Wienberg Law Genetic drift Inbreeding Genetic Bottleneck Outbreeding Founder event Effective population size Gene flow.

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Presentation on theme: "Population Genetic Hardy-Wienberg Law Genetic drift Inbreeding Genetic Bottleneck Outbreeding Founder event Effective population size Gene flow."— Presentation transcript:

1 Population Genetic Hardy-Wienberg Law Genetic drift Inbreeding Genetic Bottleneck Outbreeding Founder event Effective population size Gene flow

2 Population Genetics Genotype, phenotype locus, genotype frequency, allele frequency

3 Determining the genotype for an enzyme in a fish.

4 IDHP (isocitrate dehydrogenase) from a grasshopper Individuals 1 2 3... AA aa Aa

5 Genotype and Phenotype Genotypes  AA, aa (Homozygous), Aa (Heterozygous)‏ Phenotype trait X = AA and Aa, trait Y = aa Alleles  A and a If p = proportion of allele A and if q = proportion of allele a Then p+q = 1 Knowing p and q the Hardy-Wienberg Equilibrium gives the expected frequency of the three genotypes as: (p+q) 2 = p 2 +2pq + q 2 = 1 AA = p 2, aa = q 2 and Aa = 2pq

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7 Hardy-Wienberg Equilibrium Assumptions Population size is very large Random mating is occurring No mutation is taking place No immigration (geneflow) No selection is occurring

8 Genetic drift

9 Inbreeding A alleles common by descent

10 Effective population size Founder effect Genetic bottleneck Outbreeding depression Gene flow


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