1. BioSciencs Foro November 8th, New York Joaquin Guinea Chairman of BIOMADRID (www.biomadrid.org)www.biomadrid.org

2. 288,800 people employed in the high technology sectors (10.7% of the working population). Investment in R&D: 2,400 million euros (1.76% of the GDP). 40,000 workers in R&D. 15 universities and more than 50 academic research centres. 230,000 university students and 2,000 doctorate students every year. 27.3% of Spanish scientists are in Madrid and they produce 31% of the scientific publications in Spain. More than 20 technology transfer centres. Three fully operating scientific parks and another three under construction. GLOBAL DATA ON THE REGION OF MADRID R&D

3. 37 companies fully dedicated to biotechnology are located in Madrid (32% of the total spanish companies). 83% of the investment in R&D by biotechnology companies in Spain takes place in Madrid. 400 biomedical companies (with around 25,000 workers) are located in Madrid. 5,000 Life Sciences researchers work in academic centres in Madrid. 31% of the Spanish biomedical scientific publications have its origin in Madrid. More than 300 new PhD graduates in Life Sciences every year. More than 25,000 patients involved in more than 1,000 clinical trials every year, in 75 hospital centres. MADRID BIOSCIENCE REGION IN FIGURES

5. SOME EXAMPLES OF MADRID BIOTECH COMPANIES R&D PROJECTS Cell Therapy based on the use of stem cells obtained from adults. Generation of new therapeutic molecules based on antibodies for treatment of degenerative and inflammatory infectious diseases. Development of genetic engineering tools for medical diagnosis, the agro-food industry and environmental control (clinical and molecular diagnosis). Development of precision analytical equipment by means of biosensors (nanobiotechnology). New systems to produce recombinant proteins in genetically modified plants (with application in chemical&food industry) or from insect larvae (with application in animal health). Diagnosis and treatment of allergies by development of an individualized molecular immunotherapy.

6. BIOTECH SECTOR SUPPORT FROM PUBLIC SECTOR EUROPEAN COMMISION SPANISH GOVERNMENT Ministery of Education Ministery of Industry MADRID REGIONAL GOVERNMENT Directorate General of Technological Innovation Madrid Development Agency (IMADE) PROMOMADRID MADRID CITY COUNCIL