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Polypetides and proteins

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Presentation on theme: "Polypetides and proteins"— Presentation transcript:

1 Polypetides and proteins
L.O.: Explain the formation of a peptide (amide) linkage between α-amino acids to form polypeptides and proteins. Describe the acid and alkaline hydrolysis of proteins and peptides to form α-amino acids or carboxylates. Exam qs

2 Formation of a dipeptide between glycine and alanine
Peptide: compound containing amino acids linked by peptide bonds. Peptide bond: amide bond in proteins and peptides.

3 Formation of a dipeptide between glycine and alanine
Draw an alternative dipeptide made from the condensation of glycine and Alanine.

4 Alternative reaction of alanine and glycine
4

5 Section of a polypeptide showing four different amino acids
5

6 Acid hydrolysis of a dipeptide
Reaction conditions: reflux with HCl for 24 hours. 6

7 Alkaline hydrolysis of a polypeptide chain
Reaction condition: NaOH, heat Note: sodium salts are formed. 7

8 Peptide hydrolysis (powerPoint)

9 Draw the organic products formed when the following protein is heated with concentrated hydrochloric acid:


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