1. The chemical senses Chapter 9

2. The Taste Bud

3. Taste Transduction Salty – Na+ goes through sodium channels Sour – H+ ions block potassium channels Sweet – much more complicated (second messenger system) Bitter – again complicated, some evidence for interesting genetic differences (PTC and supertasters)

4. Distribution of taste receptors

5. Central taste pathways

6. Olfactory anatomy

7. Olfactory receptors

8. Olfactory transduction

9. Central olfactory pathways

10. The vomeronasal system – a pathway for pheromones?

11. McClintock and menstrual synchrony Women who live together tend to menstruate at the same time Study 1: diary study of menstrual cycles in 135 Wellesley College dormitory residents Study 2: direct manipulation by using exposure to odorless axillary secretions influenced length of menstrual cycles

12. Claus Wedekind and the odour of love 1.The MHC complex is a set of genes that code for proteins that are involved in the immune system 2.It is better to reproduce with individuals whose MHC complex is different to your own 3.The MHC genes also affect the smell of mouse urine 4.Female mice prefer the smell of male urine that comes from critters with a different kind of MHC

13. Wedekind’s dirty T-shirts 1.Wedekind had men wear T-shirts for 2 days without wearing anything perfumed 2.He then placed them in boxes and asked women to rate the attractiveness of the odour 3.Women preferred the T-shirts of men who had dissimilar MHC complex “It smells like my boyfriend” 4.Not so keen on T-shirts from men who had similar MHC complex “It smells like my dad”

14. The progesterone connection 1.In mice, MHC odour preference switches during pregnancy 2.In women using birth control pills, MHC preference also switches