1. Institute of Systems Biology (INBIOSIS)/ School of Biosciences & Biotechnology (Faculty of Science & Technology), Bioinformatics Development in Malaysia Zeti, A.M.H. zeti@ukm.my

2. Introduction 5 main objectives:- To develop national biotechnology information network To undertake development of database in biotechnology of national importance To develop human resource development program To provide the necessary infrastructure, connectivity and resources for bioinformatics To develop R & D program in biocomputing, genome informatics, molecular modeling and software development

3. National Biotechnology Policy (April 2005) TARGET BIOTECHNOLOGY SECTORS Agricultural Biotechnology Healthcare Biotechnology Industrial Biotechnology Bioinformatics

4. 1. National Biotechnology Information Network Started in April 1998 NBBnet a distributed network with users from local universities and RIs based at MGI Interim Facility at UKM-MTDC Smart Technology Centre

5. 2. Development of Biotechnology Databases

8. 3. Human Resource Development Program Young Lecturer Scheme PhD program abroad various funding bodies MSc/PhD

9. 3. Human Resource Development Program INTAKE2003/20042004/20052005/20062006/20072007/2008 BSc1815111821 MSc///1013 PhD////2

10. 4. Infrastructure, connectivity and resources hosted at SGI server and workstations X86-based server and workstations Power PC workstation Cluster Systems Grid Systems

11. Bioinformatics infrastructures provided by

12. 4. Infrastructure, connectivity and resources

13. Another hub for bioinformatics Integrating Proteomics, Transcriptomics, Metabolic Profiling and Bioinformatics to reveal the Biology of Plants and Microbes www.ukm.my/inbiosis

14. 5. R & D Programs Computational Biology Genome Informatics Structural Bioinformatics Systems Biology

15. 5. R & D Programs Ministry of Science, Technology & Innovation BIOTEK Science-Fund Ministry of Higher Education Fundamental Research Grant Scheme

16. Projects by approved research area

17. 9 th Malaysia Plan RESEARCH PROJECTS Genomics and Molecular Biology Initiative - Approved Projects

18. Bioinformatics Projects @ UKM Development of Novel Technology for Accurate Function Prediction based on Protein 3D Structure and Molecular Interaction Information Development of Accelerator Hardware and Software Solutions for Genome Informatics Applications in silico proteomics analysis of tunicate proteins Functional Annotation of Predicted Protein Interaction Structural Bioinformatics on various proteins of interest (collaboration with wet lab people)

19. Bioinformatics Projects @ UKM Dynamic Simulation of Terpenoid Pathway Integrating genomic and proteomic data with structural bioinformatics: completing the picture in mitragyna metabolic pathway Modeling of Fatty Acid Biosynthetic Pathway in Plant Development and Application of Machine Learning Techniques to Biological Systems

20. Society 18th May 2005 (officially registered: 8th Dec 2006) www.masbic.org

21. Call for collaboration THANK YOU VERY MUCH FOR YOUR ATTENTION