1. SPI USA, Inc. 4,5/4,5 CM A Brief Overview of SPI USA, Inc.: Location, People, Activities, and Outlook By Elia Cossis Your Partner for Innovation SPI USA, Inc. 5523 Research Park Drive, Suite 325 Baltimore, MD 21225 Phone: 443.543.5530 E-mail: info@usaspi.com

2. Location  SPI USA is located at bwtech@UMBC, a 41-acre Research & Technology Park located just outside of the University of Maryland, Baltimore County (UMBC) campus

3. Location [cont.]

4.  SPI USA is located along the Baltimore-Washington corridor and has a large concentration of life sciences research institutions and industry  Maryland’s growing life sciences industry has more than 5,500 biotechnology jobs and another 3,400 jobs in pharmaceuticals

5. Location [cont.]  A distinct advantage of being in the bwtech@UMBC Research and Technology Park is the proximity of the campus to other prominent research institutions  SPI USA is 15 minutes from downtown Baltimore and 30 minutes from the Washington DC beltway

6. Location [cont.]

8. People  Dr. Antonio Moreira – Principal Consultant/ Executive Vice President  Edward Sybert – Senior Consultant/Trainer  Elia Cossis – Consultant/Business Dev.  Nicole Hawkins – Project/Office Manager  Tania Monterastelli – Associate (P/T)

9. Activities  SPI USA’s activities are divided into the following areas: 1)BioGMP training software 2)US Training Seminars 3)International Training Seminars 4)US Consulting 5)International Consulting

10. Activities [cont.] BioGMP™ Training Software  In mid 2005, SPI USA updated the BioGMP ™ software content to reflect current changes to FDA CGMP regulations  Sold about 10 BioGMP™ software packages in 2005 independent of seminar sales  Submitted proposals to the State for funding to support the development of a new BioGMP ™ Net software product

11. Activities [cont.] US and International Seminars 2005  CGMP Training Seminars  4 US (Las Vegas, San Francisco, Boston, Philly)  4 Intl. (Brazil, London, Toronto, Rome)  GLP Training Seminar  2 US (Philadelphia, Boston)  Medical Devices Training Seminars  1 US (Boston)  2 Intl. (Paris, Amsterdam)

12. Activities [cont.] US and International Seminars 2006  CGMP Training Seminars  3 US (New Hampshire, Philadelphia, Seattle)  3 Intl. (London, Brazil, Germany)  GLP Training Seminars  2 US (San Francisco, Boston)  1 Intl (Amsterdam)  GCP Training Seminars  2 US (Baltimore, San Diego)

13. Activities [cont.] US and International Seminars 2006 [cont.]  Bio-Production Training Seminars  2 US (Washington, San Francisco)  1 Intl. (Ireland)  Medical Devices Training Seminars  3 US (Miami, New Hampshire, Minneapolis)  2 Intl. (Ireland, Amsterdam)

14. Activities [cont.] International and US Consulting 2005  International Consulting Projects  Atral-Cipan (ongoing)  KACTS (Saudi Arabia/pending)  JMS Singapore (complete)  US Consulting Projects  McKesson (complete)  FDA (complete)  Colorado State University (complete)  Omnia Biologics (pending)  Becton Dickenson (complete)  IntelliTECH (pending)

15. Outlook for 2006  Consulting Strategies for SPI USA, Inc. in 2006 Develop business with the World Bank, USAID, IDB and other agencies headquartered in the Washington DC area Develop a closer working relationship with the SPI USA Irvine office Continue to focus strongly on the biotechnology and pharmaceutical sectors utilizing in-house expertise Diversify project areas to focus on market studies, feasibility studies, sector assessments, strategic alliances, innovation and partnership development Develop new partnerships with training and consulting organizations/companies to collaborate on proposal preparation, projects and training

16. Outlook for 2006 [cont.]  Target income for 2006 is around $500,000 BioGMP and BioGMP Net sales: $100k International seminars: $100k US seminars: $150k International and US consulting: $200k

17. USA Inc. 5523 Research Park Dr., Suite 325 Baltimore, MD 21228 Tel: +1 443 543 5530 Fax: +1 443 543 5533 info@usaspi.com www.usaspi.com SPI USA Contact Information California USA – Irvine 2102 Business Center Drive, Suite 220E Irvine, CA 92612 Tel: +1 949 253 5702 Fax: +1 949 253 5703 spiusa-irvine@usaspi.com Maryland