1. Chemical, Radiological and Nuclear Weapons Session 8 Pre-recorded YSU – Weapons of Mass Destruction Course

2. This Session Chemical Weapons –Action on the Body –Comparison of Chemical Properties –Method of Treatment Radioactivity –What is it? –Types of radiation

3. This Session Radiological Dispersion Devices –How explosives work –Why radiological devices are a problem Nuclear Weapons –How they work –Practicality

4. Keep In Mind Chemical Differences in Agent –In standard conditions The Difficulty in Dissemination How They Affect People The Purpose of the Agent

5. Dissemination Aerosolized Pressurized Cylinder Heavy Spray Liquid Evaporative Surfaces and Foods

6. Group Name - Vesicants Mustard (H) Lewisite (L) Dichloroarsine (PD) Nitrogen Mustards (HN) Latin vesica meaning bladder or vessel that holds liquid. S, As and N-based blister agents. Military classes C07, 08 and 09

7. Mustard C4-H8-C12-S M.W. 159.08 Colorless to Yellow Oily Liquid Garlic Odor BP – 215C MP – 13C High lipid solubility/low water.68mg/L Vapor Density = 5.4 Vapor Pressure = 0.11 mm Hg

8. Action on The Body Some have chemotheraputic use Damage DNA (similar to radiation) Prevent cell division Edema of lungs, skin blisters Pain and swelling of mucosa 1-12 hrs for effect preceded by red skin Death from asphyxiation??

9. Vesicants – Typical Treatment Remove clothes – light bleach decon Arsenicals will decon in water Pain Management Intubation may be required No antidotes except British anti-Lewisite

10. Group Name – Nerve Agents Soman (GD) Tabun (GA) Sarin (GB) VX VX2 Similar to Nitrogen-Phosphorous Pesticides Military agents C-01, 02, 03, 04, 05 and 06

11. VX Less than 1 drop of VX will cause death Persistent in soil for 2-6 days

12. VX C11-H26-N-O2-P-S MW – 267.37 Odorless/Colorless to straw color BP – 298C MP – -51C High lipid solubility/soluble in cool water 30 g/L Vapor Density = 9.2 Vapor Pressure = 0.0007 mm Hg

13. Nerve Agents – Action on the Body Inhibition of cholinesterase Pinpoint pupils Profuse runny nose, sweating, nausea Urination/defecation Convulsions progress to paralysis Vapors may cause chest discomforts Pulmonary edema Cessation of breathing from edema or exhaustion/CA

14. Nerve Agents – Typical Treatment Atropine and 2 PAM Chloride may aid in airway restrictions and profuse fluids Diazepam anti-convulsant Remove clothing Decon with soap and water Decon with mild hypochlorite

15. Group Name - Asphyxiants Chloropicrin Chlorine Diphosgene Phosgene Also called choking agents. Military agents C14 and 15

16. Chlorine Cl2 MW – 70.906 Yellow Green-noxious odor gas BP – -34.04C MP – -105C Corrosive to plastics and rubber Vapor Density = 2.5 Vapor Pressure = 5830 mm Hg

17. Asphyxiants – Action on the Body Displacement of oxygen At 1-3 ppm mild irritation of lungs At 30 ppm chest pain, cough, dyspnea At 40 ppm pneumonitis, edema At 430 ppm lethal over 30 minutes At 1000 ppm lethal in a few minutes

18. Asphyxiants – Typical Treatment ABCs (Airway, breathing, circulation) Oxygen therapy Halogens may produce chemical burns Flush skin with cool water Bandages may stick to skin Decon with water if necessary but most have high V.P.

19. Group Name – Blood Agents Arsine gas Cyanogen chloride Hydrogen cyanide Military Classes C-12 and 13 May be Arsenic or Cyanide-based

20. Hydrogen Cyanide C-H-N MW – 27.03 Sweet to bitter almond-like. May be colorless to lt. blue liquid, gas above 78F BP – 25C MP – -13.4C Solubility 1,000,000 mg/L Vapor Density = 0.94 Vapor Pressure = 742 mm Hg

21. Blood Agents – Action on the Body Inhibit the binding of oxygen or CO 2 /O 2 exchange Palpitation cyanosis, dyspnea Low doses may produce symptoms over an hour Anxiety, confusion, vertigo, numbness, salivation, rapid, then slow irregular respiration, vomiting, giddiness BP rise, HR lower, Pink Skin (in some)

22. Blood Agents – Typical Treatment If arsenical agent a light vinegar solution may be used for decon otherwise water (but many have high V.P.) Remove from scene + O 2 therapy Blood transfusion may be necessary

23. Group Name - Urticants Agent CX Phosgene Oxime T-2 Mycotoxin Military class C-11 T-2 toxin is also classified as C-23 dermal biotoxin From Latin urtica which is a stinging nettle plant. Latin urticare means itching or stinging.

24. Trichothecene (T-2) C24-H34-O9 MW – 466.53 MP – 150C White crystalline solid Solubility - most common solvent

25. Urticants – Action on Body Airborne – pulmonary hemorrhage Ingest – hempoietic difficulties DNA damage, protein synthesis inhibitor Extreme itching to excruciating dermal pain Ocular pain, gastrointestinal bleeding Hypotension

26. Urticants – Typical Treatment Remove clothing Irrigate eyes and skin with water Decon with soap and water Move to fresh air Inhaled bronchiodialator Dopamine or norepi for hypotension Platelets or plasma may be necessary

27. Group Name - RCAs Bromobenzylcyanide Chloroacetophenone Pepper Spray Agent OC Military classes C-17, 18 and 19. Class C-16 are incapacitating agents that may be RCAs as well

28. Chloroacetophenone C8-H7-Cl-O MW – 154.6 Colorless to white crystalline solid BP – 244C MP – 58C Solubility: insol. in water – sol. in alcohol Vapor Density = 5.32 Vapor Pressure =.0054 mm Hg

29. What is Radioactivity? Elements have atomic mass numbers Mass is the number (weight) of the protons and neutrons in the nucleus Some elements can have different forms –Uranium 233, 235, 238 all have 92 protons

30. Atom Protons + Neutrons = AM Number 92 Protons + 146 Neutrons = Uranium 238

31. Radioactivity Most elements are very stable Radioactive elements want to change They can lose parts of themselves spontaneously. This is called decay. –Alpha particles –Beta particles –Gamma rays

32. Decay Products Alpha Particle –Helium 4 nucleus is given off –High energy –Cannot penetrate a sheet of paper –Will travel up to 10 cm –Can be carried into the air –Ionizing

33. Decay Products Beta Particle –High speed electron –Ionizing –Can penetrate human skin, wood, clothes –Emits x-rays as it slows –Travels up to 9 meters –Can cause skin burns

34. Decay Products Gamma Rays –Very high energy –Short wavelength –Travels at speed of light –Penetrates steel –Not particles - photons

35. Concern with Radiation Some radioactive elements have a very long half-life. A half-life is the amount of time it takes for the element to become half as radioactive as it was at the starting point. This can be days to thousands of years depending on the element.

36. Radiological Dispersion Device Dirty Bomb Traditional explosive device core Radioactive elemental inner shell Intended to scatter debris and particles Waste nuclear material can come from chem labs, from old equipment, RIA clinical procedures, nuclear medicine waste and power plant rods.

37. Health Effects Cell damage Chromosomal changes Free ions destroy tissue Damage bone marrow and lymphatics Immune changes TIME DISTANCE SHIELDING

38. Standard Explosive Devices Exothermic Process –Add NaOH to Water –Burn Gasoline Endothermic Process –Ice Melting

39. Explosive Process Chemicals are elements + bonds Certain combinations store high energy Trinitrotoluene, Ammonium picrate Primary Explosive (detonator) –Very sensitive to heat, shock, spark etc. Secondary Charge –Packs punch Main Charge

40. Nuclear Reaction Fission Device –If you can split the nucleus of a radioactive element, you can release very high energy –Weapons and powerplants –Bombardment of neutrons –When a nucleus is struck it gives off avg. of 2.4 neutrons. –If atoms are not compact, the reaction will not continue

41. Nuclear Reaction If the mass is more dense the fission can become a chain reaction because the free neutrons can strike more nuclei The amount of an element necessary to carry on this chain is called critical mass. For a weapon, a supercritical mass is used producing a devastating chain reaction and an enormous exothermic reaction.

42. Our Fortune Nature only allows us to accomplish this with a few radioactive materials. It is difficult to refine these elements into weapons-grade material 100 pounds of element will probably yield less than a few ounces of weapons-grade element.

43. Up and Coming Special exercise Monday and Wednesday Simulated incident Mod. 3 papers due on March 1 at 11PM Please turn in your short answer question before 11:00 PM on Friday.