1. Organelles – Part I

2. Organelles Organelles are ‘tiny organs.’Organelles are ‘tiny organs.’ –Organs are to humans as organelles are to cells.

3. Nucleus Function:Function: –The nucleus is the cell’s genetic control center. Stores DNAStores DNA Makes RNAMakes RNA Makes ribosomesMakes ribosomes Directs the synthesis of proteinsDirects the synthesis of proteins

4. Nucleus Structure:Structure: –The nucleus has 3 parts: It is surrounded by the nuclear envelope (membrane) that has tiny pores which material can pass into and out of the nucleus.It is surrounded by the nuclear envelope (membrane) that has tiny pores which material can pass into and out of the nucleus. Inside it containsInside it contains –DNA »When DNA is spread out it is called chromatin. »When DNA is coiled up it is called chromosomes. –The nucleolus, which appears as a dark spot inside the nucleus, manufactures ribosomes.

5. Nucleus Structure:Structure: –The nucleus has 3 parts: Inside it containsInside it contains –DNA »When DNA is spread out it is called chromatin. »When DNA is coiled up it is called chromosomes.

6. Nucleus Structure:Structure: –The nucleus has 3 parts: –The nucleolus, which appears as a dark spot inside the nucleus, manufactures ribosomes.

7. Nucleus Chromatin Nucleolus Pore Ribosomes Rough endoplasmic reticulum Two membranes of nuclear envelope

8. Ribosomes Function:Function: –Ribosomes manufacture proteins based on instructions they get from the DNA in the nucleus. Structure:Structure: –Ribosomes are small spherical structures. –They float in the cytoplasm OR are connected to the rough ER. –They are composed of proteins & RNA.

9. Ribosomes

10. Endoplasmic Reticulum (ER) There are two types of ER:There are two types of ER: –Smooth ER –Rough ER

11. Smooth ER Function:Function: –The smooth endoplasmic reticulum has a variety of functions: Synthesizes lipidsSynthesizes lipids Processes toxins and drugs in liver cellsProcesses toxins and drugs in liver cells Stores and releases calcium ions in muscle cellsStores and releases calcium ions in muscle cells Structure:Structure: –Smooth endoplasmic reticulum is composed of flattened sacs that often extend throughout the entire cytoplasm

12. Rough ER Function:Function: –The rough ER has three functions: Synthesis of proteins (in the attached ribosomes)Synthesis of proteins (in the attached ribosomes) Modification of proteins.Modification of proteins. Packing of proteins.Packing of proteins. Structure:Structure: –Rough endoplasmic reticulum is the same as the smooth but it is dotted with ribosomes which make it bumpy.

14. Golgi Apparatus (Golgi Bodies) Function:Function: –They receive and modify ER products then modify, sort, package and ship them to other organelles or the cell surface. Structure:Structure: –The Golgi apparatus looks like stacks of membranous sacs.

16. Lysosomes Function:Function: –They contain enzymes that break down: FoodFood Damaged organellesDamaged organelles Bacteria with which they fuse.Bacteria with which they fuse. Structure:Structure: –Lysosomes are made by the Golgi Apparatus. –They are tiny spheres of enzymes

18. Interesting Facts… Abnormal lysosomes can cause fatal diseases.Abnormal lysosomes can cause fatal diseases. When a cell is damaged the nucleus sends a message to the lysosome telling it to explode – the enzymes inside eat the cell – for this reason we also call lysosomes ‘suicide sacs’When a cell is damaged the nucleus sends a message to the lysosome telling it to explode – the enzymes inside eat the cell – for this reason we also call lysosomes ‘suicide sacs’

19. Huntingdon’s disease

20. Pompe’s disease

21. Tay-sachs disease

22. Vacuoles Function:Function: –Vacuoles can do all kinds of things. They can contain pigment (color)They can contain pigment (color) They can contain poison.They can contain poison. They have contain food or water.They have contain food or water. –Plants have central vacuoles that function store large amounts of water Structure:Structure: –Vacuole is the general term given to any other membrane sac in the cell.