1. Macromolecules CHAPTER 2.3

2. SECTION 2-1: THE NATURE OF MATTER REMEMBER… Atoms are made up of electrons (-), neutrons (neutral), and protons (+) Proton number = atomic number = type of element

3. SECTION 2-3: CARBON COMPOUNDS Organic compounds- those compounds that contain carbon Chemical Formulas - show how many and which atoms are in a compound Structural Formulas - show the arrangement of the atoms in a compound

4. Isomers - compounds with the same chemical formula, but different structure (ex. propanol and isopropanol)

5. glucose Fructose

6. COVALENT BOND #’S Atoms want to fill their electron shells. An atom wants to make just enough bonds to fill its shells. H makes one bond O makes two bonds C makes four bonds

7. MACROMOLECULES Monomers (smaller units) join to make polymers or macromolecules –Carbohydrates –Lipids –Proteins –Nucleic acids

8. CARBOHYDRATES Organic compounds composed of carbon, hydrogen and oxygen with a ratio of two hydrogen atoms to every one oxygen atom Made up of sugars

9. USE OF CARBOHYDRATES Source of energy for many living things Examples: sugar and starch

10. TYPES OF CARBOHYDRATES Monosaccharides Disaccharides Polysaccharides

11. MONOSACCHARIDES Only one sugar molecule Examples -glucose, fructose, and galactose All three are C 6 H 12 O 6, but they are isomers Draw Glucose

13. DISACCHARIDES Double sugars (two monosaccharides combined) Examples: sucrose, lactose, and maltose All are isomers with the chemical formula C 12 H 22 O 11

15. POLYSACCHARIDES Long chains of monosaccharides joined together Examples: starch, glycogen, and cellulose Plants store excess sugar as starch, and break it down for energy

17. Humans store excess sugar as glycogen, & break it down for energy Cellulose used by plants to build cell walls.

18. Carbohydrates and Nutrition Beware of low carbohydrate diets –Low carbohydrates cause your body to break down muscle (protein) –Low carbohydrates can cause your appetite to increase (your body thinks it is starving) Eat whole grains! –Whole grains provide fiber and help to prevent heart disease and cancer.

19. DEHYDRATION SYNTHESIS Two molecules join together by losing a molecule of water

21. HYDROLYSIS REACTION Larger molecules broken down into smaller molecules by the addition of water

22. LIPIDS Include fats, oils, steroids & waxes Composed of carbon, hydrogen and oxygen, but the # of H atoms per molecule is much greater then the # of O atoms An example, C 57 H 110 O 6

23. USES OF LIPIDS Stored for energy Form basic structure of cell membranes Protection Insulation Waterproof coverings

24. THE STRUCTURE OF SOME FATS Fatty Acids (a common type of fat): –a long carbon chain with a -COOH (carboxyl group) at one end

25. Different types of fatty acids: –Saturated - all single, covalent bonds in between carbons in chain –Unsaturated - one double bond between carbons in chain –Polyunsaturated - many double bonds between carbons in chain

29. Steroids include: –Cholesterol -made by animals and is both helpful & harmful –Testosterone/Estrogen – male/female hormones –Cortisone – medicine used to reduce swelling/itching

31. Fats and Nutrition Unsaturated fat is better for you than saturated fat. Double bonds are easier to break than single bonds. High fat diet actually increases appetite. To increase fat break down, you must increase physical activity. Good fats are found in some fish, olives, and nuts and actually help to prevent heart disease.

32. PROTEIN Made up of amino acids linked together Composed of C, H, & O as well as nitrogen, N, and possibly sulfur

33. USES OF PROTEINS Build living materials like muscle Act as enzymes to help carry out chemical reactions Fight disease Transport particles into or out of cells Act as markers on cells

34. AMINO ACID STRUCTURE Have a central C that is bound to: –carboxyl group (-COOH) –a hydrogen atom –a amino group (-NH2) –an “R” group

36. AlanineSerine General structure

37. There are 20 main amino acids. Each has same basic structure with the only difference being the “R” group Amino acids are linked by peptide bonds (formed by dehydration synthesis)

38. Peptide bond is between two amino acids Polypeptide – (a protein) many amino acids joined

40. Protein and Nutrition Proteins help to suppress appetite so eat a little at every meal. Proteins help build lean body mass. Increased lean body mass increase your BMR (basal metabolic rate). –This means that you burn more calories. Yo-yo dieting decreases BMR and makes your body store fat.

41. NUCLEIC ACIDS Composed of nucleotides Nucleotides consist of a sugar, a nitrogenous base, and a phosphate Nucleic acids include: DNA, RNA, ATP, and NAD