1. SU: DNA The diagram shows Rosalind Franklin’s x-ray diffraction image of DNA. How did this evidence affect the work of Watson and Crick? –A. It was used to determine the physical structure of DNA. –B. It was used to identify the four bases that make up DNA. –C. It was used to develop the theory of independent assortment. –D. It was used to show that DNA was the molecule of inheritance.

2. Class Business Gattaca Essay Due tomorrow – 30 HP! Writing across the curriculum prompt due tomorrow: –In one paragraph describe photosynthesis! Outline 12-2 Due on Tuesday (5HP) Reading Quiz 12-2 on Tuesday Outline 12-3 Due Thursday (10HP) Reading Quiz 12-3 on Friday

11. HOMEWORK Gattaca Essay Due tomorrow – 30 HP! Writing across the curriculum prompt due tomorrow: –In one paragraph describe photosynthesis! Outline 12-2 Due on Tuesday (5HP) Reading Quiz 12-2 on Tuesday Outline 12-3 Due Thursday (10HP) Reading Quiz 12-3 on Friday

12. SU: Base-Pairing Which base sequence in DNA is complementary to the base sequence TATCGG –A. ATAGCC –B. UCUATT –C. GCGUTT –D. ATACAA –Hint: Use Chargaff’s Rule

13. Classroom Business GATTACA Essay/ Genetic Engineering Essay Writing across the curriculum: In one paragraph describe the process of photosynthesis Outline 12-2 Due Tuesday, Quiz Tuesday Outline 12-3 Due Thursday, Quiz Friday No school tomorrow. Sub on Monday: –Use the workbooks. Section 12-2

19. DNA – deoxyribonucleic acid 3 Functions of DNA: 1.To store and use information to direct the activity’s of the cell 2.To copy itself exactly in order to form new cells 3.Must be able to pass copies of their DNA to offspring in order to keep species from going extinct

20. DNA Nucleotides Made of 3 parts: 1. phosphate molecule 2. sugar molecule – deoxyribose 3. nitrogen base – can be 1 of the 4 below: - adenine- thymine - cytosine- guanine **sugar & phosphate molecules are ALWAYS THE SAME IN EVERY NUCLEOTIDE

21. Create your own DNA Molecul e On the back of your nucleotide handout write.. –3 Red “A” - Adenine –3 Green “T” - Thymine –3 Blue “C” – Cytosine –3 Yellow “G” – Guanine –12 Black “Phosphate Groups” –12 White “ Sugar” - Deoxyribose

22. Directions to make your own DNA Model Follow Chargoff’s Rules! Step 1: Cut out templates. Step 2: Cut your nucleotides Step 3: Pair your nucleotides together. Step 4: Link them together with the sugar and phosphate groups. Step 5: Sit back and look with awe at your completed DNA molecule.

23. Answer the following questions in your notebook… Choose one side of your DNA molecule to be your leading strand. –What is your final DNA sequence? What is your final complementary sequence? –This is the DNA strand that is opposite your leading strand. Make a prediction what would happen if you made a mistake in your DNA molecule. Would the structure be different? Would the nucleotides match? What do you think happens when this occurs inside your cells?

24. HOMEWORK Gattaca Essay Due tomorrow – 30 HP! Writing across the curriculum prompt due tomorrow: –In one paragraph describe photosynthesis! Outline 12-2 Due on Tuesday (5HP) Reading Quiz 12-2 on Tuesday Outline 12-3 Due Thursday (10HP) Reading Quiz 12-3 on Friday

25. SU: DNA Structure The two chains of a DNA molecule are held together by bonds between… –A. Base Pairs –B. Sugars and Phosphates –C. Amino Acids –D. Nucleotides

26. Class Business Outline 12-2 Due Today Reading Quiz 12-2 Quiz Today Outline 12-3 Due Thursday Reading Quiz 12-3 Friday DNA Molecule

27. Review: Structure of DNA Hydrogen bonds Nucleotide Sugar-phosphate backbone Key Adenine (A) Thymine (T) Cytosine (C) Guanine (G) Section 12-1 Go to Section:

28. AdenineGuanine Cytosine Thymine Phosphate group Deoxyribose Review: DNA Nucleotides Section 12-1 Go to Section:

31. Structure of Chromosomes Vocabulary –Chromatin –Histones

40. DNA Replication Vocabulary –Replication –DNA Polymerase

45. Homework Outline 12-3 Due Thursday Reading Quiz 12-3 on Friday

46. 3:2:1 Exit Slip 3 Things you learned today 2 Things that you did not expect 1 Question for further inquiry