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Dan-Thanh Nguyen Biology 402 March 20, 2012
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Symptoms: Fever Sore throat Weakness Headache Muscle aches Diarrhea Vomiting Severe hemorrhaging
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http://www.all-science-fair-projects.com/science_fair_projects_encyclopedia/Ebola
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http://www.reviews-technology.com/2010_08_24_archive.html
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http://www.mnzoo.org/faces/fruit-bat /
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http://www.who.int/csr/disease/ebola/Global_EbolaOutbreakRisk_20090510.png
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277274/?tool=pmcentrez
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Zaire (Democratic Republic of Congo) Sudan Cote d’Ivoire (Ivory Coast) Reston Bundibugyo
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http://viralzone.expasy.org/all_by_species/23.html
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Nucleoprotein Virion protein 35 Virion protein 40 Virion protein 30 Virion protein 24 Glycoprotein Soluble glycoprotein polymerase http://viralzone.expasy.org/all_by_species/23.html
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277274/?tool=pmcentrez
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Hepatocytes Endothelial cells Dendritic cells Monocytes Macrophages
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http://www.nature.com.libproxy.lib.unc.edu/nri/journal/v3/n8/full/nri1154.html#f3
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http://www.nature.com.libproxy.lib.unc.edu/nri/journal/v7/n7/full/nri2098.html
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http://jid.oxfordjournals.org/content/188/11/1618.full
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http://buquad.com/2011/10/17/bu-biolab/ http://www.nationalpost.com/related/topics/Canadian+scientists+develop+Ebola+treatment/3083100/story.html
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Dolnik, O.; L. Kolesnikova, and S. Becker. “Filoviruses: Interactions with the host cell.” Cellular and Molecular Life Sciences Vol 65. 756-776. 2008. http://www.springerlink.com/content/fk38279221156248/ http://www.springerlink.com/content/fk38279221156248/ “Ebola haemorrhagic fever.” World Health Organization. Dec 2011. http://www.who.int/mediacentre/factsheets/fs103/en/ http://www.who.int/mediacentre/factsheets/fs103/en/ “Ebola virus disease.” Wikipedia. http://en.wikipedia.org/wiki/Ebola_virus_diseasehttp://en.wikipedia.org/wiki/Ebola_virus_disease Feldmann, Heinz; Steven Jones, Hans-Dieter Klenk; and Hans-Joachim Schnittler. “Ebola virus: from discovery to vaccine.” Nature Reviews Immunology. Vol 3. 677-685 (August 2003). http://www.nature.com.libproxy.lib.unc.edu/nri/journal/v3/n8/full/nri1154.html#f3 http://www.nature.com.libproxy.lib.unc.edu/nri/journal/v3/n8/full/nri1154.html#f3 Geisbert, Thomas et al. “Mechanisms Underlying Coagulation Abnormalities in Ebola Hemorrhagic Fever: Overexpression of Tissue Factor in Primate Monocytes/Macrophages is a Key Event.” Journal of Infectious Diseases. Vol 188. 1618-1629. 2003. http://jid.oxfordjournals.org/content/188/11/1618.full.pdf+html http://jid.oxfordjournals.org/content/188/11/1618.full.pdf+html Mohamadzadeh, Mansour; Leiping Chen; and Alan L. Schmaljohn. “How Ebola and Marburg viruses battle the immune system.” Nature Reviews Immunology. Vol 7. 556-567 (July 2007). http://www.nature.com.libproxy.lib.unc.edu/nri/journal/v7/n7/full/nri2098.htmlhttp://www.nature.com.libproxy.lib.unc.edu/nri/journal/v7/n7/full/nri2098.html Takada, Ayato. “Filovirus Tropism: Cellular Molecules for Viral Entry.” Frontiers in Microbiology. 06 February 2012. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277274/pdf/fmicb-03-00034.pdf http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277274/pdf/fmicb-03-00034.pdf
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