1. © 2012 International Business Machines Corporation IBM Watson in Health Care Joel Farrell, IBM MedBiquitous Annual Conference 2013

2. 2 © 2012 International Business Machines Corporation  90 x IBM Power 750 1 servers  2880 POWER7 cores  POWER7 3.55 GHz chip  500 GB per sec on-chip bandwidth  10 Gb Ethernet network  15 Terabytes of memory  20 Terabytes of disk, clustered  Can operate at 80 Teraflops  Runs IBM DeepQA software  Scales out with and searches vast amounts of unstructured information with UIMA & Hadoop open source components  SUSE Linux provides a cost-effective open platform which is performance-optimized to exploit POWER 7 systems  10 racks include servers, networking, shared disk system, cluster controllers Watson Workload Optimized System (Power 750) – Original 1 Note that the Power 750 featuring POWER7 is a commercially available server that runs AIX, IBM i and Linux and has been in market since Feb 2010

3. 3 © 2012 International Business Machines Corporation Watson Today 1 to 4 p750's 16 cores 256 GB RAM Enhanced core algorithms Large case question Health care specific reasoning Health language normalization New health care specific scoring New NLP processors New Data Engine New Data Model

4. 4 © 2012 International Business Machines Corporation Key Differences Between Jeopardy and Healthcare 08/10/11 JeopardyHealthcare Single, known correct answer Multiple possible answers, “best” may be debatable No substantiating evidence allowedSubstantiating evidence essential Single dimensional input from one sourceMulti-dimensional input from multiple sources No dialogue/interaction by/with system Interaction by/with system – “prompting” for information Fixed repositoryDynamic repository Evidence profile and underlying algorithms based on trivia questions Evidence profile and underlying algorithms based on medical questions Consequence: Significant development required

5. 5 © 2012 International Business Machines Corporation Administrative Simplification PhysicianPatient Physician records symptoms, medical history, and vitals Physician determines patient is at risk for breast malignancy and wants a breast MRI. Staff requests MRI pre-authorization from WellPoint Utilization Management (UM) UM RN reads the pre-auth request (fax/email/transcribed vm) and creates a summary. RN queries Watson and reviews Watson’s recommendation Clinical staff Utilization Management Registered Nurses (RN) Utilization Management Registered Nurses (RN) Utilization Management Registered Nurses (RN) Clinical staff RN makes a decision: authorize or forward request to WLP MD Administrative Simplification Process with Watson Medical Policies / Care Guidelines

6. 6 © 2012 International Business Machines Corporation Oncology Advisor Use Case Workflow Pre-Authorization Patient Oncologist Nurse Office Staff Treatment Analyzer Longitudinal Patient Health Information Care Guidelines Genetic Testing Cost Information Medical Literature Morbidity and Mortality Info Medical Policy Query for patient specific treatment options (e.g., mortality, morbidity, likelihoods) Treatment options Discuss Treatment options Create tailored treatment program and adjust as needed Presumptiv e Diagnosis Care Management Comprehensive case management Authorize full treatment program instead of each episode of care Notify additional care givers of treatment authorization Claims Management Automated claims authorization for providers in patient’s care delivery team SURGERYSURGERY EMRClaims Summary Benefits  Increase evidence based treatment  Streamline pre-auth / claims administration  Improve coordination of collaborative care Coordinated collaborative care THERAPYTHERAPY Clinical Patient Data PCPPCP