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Osteogenesis imperfecta (compression fractures). OI-blue sclera.

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Presentation on theme: "Osteogenesis imperfecta (compression fractures). OI-blue sclera."— Presentation transcript:

1 Osteogenesis imperfecta (compression fractures)

2 OI-blue sclera

3 Osteopetrosis(Albers-Schonberg)-osteoclast defect, Inc. bone mass but still brittle

4 Osteochondromatosis Risk for malignancy? Chondrosarcoma

5 Osteochondromatosis

6

7

8 Osteochondromatosis w/ cartilage cap

9 TB in the spine (eponym)?Pott’s Dz

10 TB-granulomas, giant cells

11 Calcium stain-Normal Bone

12 Ca stain-Osteoporosis (Loss of Bone density)

13 Thick skull? Paget’s Hearing loss, Inc. serum Alk Phos, Inc. urine hydroxyproline Sxs? At Risk? osteosarcoma, CHF

14 Fibrous dysplasia of the rib Polyostotic FD + Café au Lait & Early Puberty? McCune-Albright

15 Fibrous Dysplasia-too much stroma

16 Osteoid osteoma

17

18 Osteoblastoma

19 Osteosarcoma-Codman’s Triangle #1 primary mal bone

20 Osteosarcoma-kids with Rb at risk, Chr 13 del Adults with previous radiation or Paget’s

21 Osteosarcoma Telangiotic type

22 Osteosarcoma-Telangiotic type

23 Osteosarcoma-appendicular bones

24 Chondroma Oiler’s-multi (one side Of the body) Mafucci’s-multi & hemangioma

25 Chondroma

26 Chondrosarcoma-axial bones

27 Chondrosarcoma-#2 primary mal bone

28 Chondrosarcoma

29 Chondrosarcoma-single mitosis is Dx

30 Ewing’s sarcoma-t(11,22)

31 (PAS+ ) Ewing’s

32 Liposarcoma-cell type? Flouret cell (multinucleated lipoblast)

33 Liposarcoma type?Well-diff/low grade

34 Liposarcoma type? Myxoid most common t12,16

35 Liposarcoma-myxoid signet ring cells

36 Liposarcoma-Pleomorphic w/ Giant lipoblast

37 Liposarcoma-Round cell

38 Liposarcoma-ugly looking isn’t it?

39 Mal Fibrous Histiocytoma-#1 soft tissue mal

40 Mal Fibrous Histiocytoma-giant cells

41 Mal Fibrous Histiocytoma

42

43 Synovial Sarcoma-biphasic epitheloid and spindle cell

44

45 Synovial Sarcoma-not synovial tissue

46 Synovial Sarcoma


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