1. © 2013 Pearson Education, Inc. Chapter 15: Microbial Mechanisms of Pathogenicity $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Portals of Entry Bacterial Pathogens Viral Pathogens Eukaryotic Pathogens Portals of Exit FINAL ROUND

2. © 2013 Pearson Education, Inc. Topic 1: Portals of Entry $100 Question Which portal of entry is most often used by microorganisms? a. parenteral route b. mucous membranes of the respiratory route c. mucous membranes of the conjunctiva d. skin ANSWER BACK TO GAME

3. © 2013 Pearson Education, Inc. Topic 1: Portals of Entry $100 Answer Which portal of entry is most often used by microorganisms? a. parenteral route b. mucous membranes of the respiratory route c. mucous membranes of the conjunctiva d. skin BACK TO GAME

4. © 2013 Pearson Education, Inc. Topic 1: Portals of Entry $200 Question Which of the following diseases utilizes the respiratory tract as its portal of entry? a.giardiasis b.hepatitis c.influenza d.cholera BACK TO GAME ANSWER

5. © 2013 Pearson Education, Inc. Topic 1: Portals of Entry $200 Answer Which of the following diseases utilizes the respiratory tract as its portal of entry? a.giardiasis b.hepatitis c.influenza d.cholera BACK TO GAME

6. © 2013 Pearson Education, Inc. Topic 1: Portals of Entry $300 Question One disease that can be transmitted by the parenteral route is a. tetanus. b. trachoma. c. influenza. d. tuberculosis. BACK TO GAME ANSWER

7. © 2013 Pearson Education, Inc. Topic 1: Portals of Entry $300 Answer One disease that can be transmitted by the parenteral route is a. tetanus. b. trachoma. c. influenza. d. tuberculosis. BACK TO GAME

8. © 2013 Pearson Education, Inc. Topic 1: Portals of Entry $400 Question What is the portal of entry for chlamydia? a.genitourinary route b.gastrointestinal route c.skin d.respiratory route BACK TO GAME ANSWER

9. © 2013 Pearson Education, Inc. Topic 1: Portals of Entry $400 Answer What is the portal of entry for chlamydia? a.genitourinary route b.gastrointestinal route c.skin d.respiratory route BACK TO GAME

10. © 2013 Pearson Education, Inc. Topic 1: Portals of Entry $500 Question When pathogens enter the skin, they usually a.enter through the hair follicles and sweat ducts. b.penetrate intact skin. c.are injected into the skin. d.adhere to the skin and then penetrate the skin. BACK TO GAME ANSWER

11. © 2013 Pearson Education, Inc. Topic 1: Portals of Entry $500 Answer When pathogens enter the skin, they usually a.enter through the hair follicles and sweat ducts. b.penetrate intact skin. c.are injected into the skin. d.adhere to the skin and then penetrate the skin. BACK TO GAME

12. © 2013 Pearson Education, Inc. All gram-negative bacteria contain a.exotoxins. b.endotoxins. c.siderophores. d.IgA protease. Topic 2: Bacterial Pathogens $100 Question BACK TO GAME ANSWER

13. © 2013 Pearson Education, Inc. Topic 2: Bacterial Pathogens $100 Answer All gram-negative bacteria contain a.exotoxins. b.endotoxins. c.siderophores. d.IgA protease. BACK TO GAME

14. © 2013 Pearson Education, Inc. What is the action of kinases? a.coagulate fibrinogen b.hydrolyze hyaluronic acid c.break down fibrin d.break down collagen Topic 2: Bacterial Pathogens $200 Question BACK TO GAME ANSWER

15. © 2013 Pearson Education, Inc. What is the action of kinases? a.coagulate fibrinogen b.hydrolyze hyaluronic acid c.break down fibrin d.break down collagen Topic 2: Bacterial Pathogens $200 Answer BACK TO GAME

16. © 2013 Pearson Education, Inc. Which organism produces an exotoxin? a. Proteus spp. b. Neisseria meningitidis c. Staphylococcus aureus d. Salmonella typhi Topic 2: Bacterial Pathogens $300 Question BACK TO GAME ANSWER

17. © 2013 Pearson Education, Inc. Which organism produces an exotoxin? a. Proteus spp. b. Neisseria meningitidis c. Staphylococcus aureus d. Salmonella typhi Topic 2: Bacterial Pathogens $300 Answer BACK TO GAME

18. © 2013 Pearson Education, Inc. Topic 2: Bacterial Pathogens $400 Question BACK TO GAME ANSWER Which organism produces erythrogenic toxin? a. Staphylococcus aureus b. Streptococcus pyogenes c. Vibrio cholerae d. Corynebacterium diphtheriae

19. © 2013 Pearson Education, Inc. Topic 2: Bacterial Pathogens $400 Answer BACK TO GAME Which organism produces erythrogenic toxin? a. Staphylococcus aureus b. Streptococcus pyogenes c. Vibrio cholerae d. Corynebacterium diphtheriae

20. © 2013 Pearson Education, Inc. Topic 2: Bacterial Pathogens $500 Question Clostridium tetani causes the disease tetanus by producing a(n) a.endotoxin. b.exotoxin. c.capsule. d.enzyme. BACK TO GAME ANSWER

21. © 2013 Pearson Education, Inc. Topic 2: Bacterial Pathogens $500 Answer Clostridium tetani causes the disease tetanus by producing a(n) a.endotoxin. b.exotoxin. c.capsule. d.enzyme. BACK TO GAME

22. © 2013 Pearson Education, Inc. Topic 3: Viral Pathogens $100 Question Which virus irreversibly stops mitosis? a.human immunodeficiency virus b.herpes simplex virus c.rabies virus d.measles virus BACK TO GAME ANSWER

23. © 2013 Pearson Education, Inc. Topic 3: Viral Pathogens $100 Answer Which virus irreversibly stops mitosis? a.human immunodeficiency virus b.herpes simplex virus c.rabies virus d.measles virus BACK TO GAME

24. © 2013 Pearson Education, Inc. Topic 3: Viral Pathogens $200 Question Which virus causes basophilic inclusion bodies to accumulate in the nucleus? a.adenovirus b.rhabdovirus c.papovavirus d.cytomegalovirus BACK TO GAME ANSWER

25. © 2013 Pearson Education, Inc. Topic 3: Viral Pathogens $200 Answer Which virus causes basophilic inclusion bodies to accumulate in the nucleus? a.adenovirus b.rhabdovirus c.papovavirus d.cytomegalovirus BACK TO GAME

26. © 2013 Pearson Education, Inc. Which of the following refers to the visible effects of a viral infection? a.lysogenic conversion b.lysogenic effects c.cytopathic effects d.cytopathic conversion Topic 3: Viral Pathogens $300 Question BACK TO GAME ANSWER

27. © 2013 Pearson Education, Inc. Topic 3: Viral Pathogens $300 Answer Which of the following refers to the visible effects of a viral infection? a.lysogenic conversion b.lysogenic effects c.cytopathic effects d.cytopathic conversion BACK TO GAME

28. © 2013 Pearson Education, Inc. Topic 3: Viral Pathogens $400 Question What are the granules found in the cytoplasm or nucleus of some virus-infected cells? a.ribosomes b.mitochondria c.lysosomes d.inclusion bodies BACK TO GAME ANSWER

29. © 2013 Pearson Education, Inc. Topic 3: Viral Pathogens $400 Answer BACK TO GAME What are the granules found in the cytoplasm or nucleus of some virus-infected cells? a.ribosomes b.mitochondria c.lysosomes d.inclusion bodies

30. © 2013 Pearson Education, Inc. Topic 3: Viral Pathogens $500 Question Why is it difficult for antibodies to destroy HIV? a.HIV undergoes antigenic variation when an antibody binds to the virion. b. HIV infects and destroys the immune cells that produce and synthesize antibodies. c. They cannot reach the binding site for CD4 on the surface of the virus. d. Antibodies that target HIV are not produced by the host. BACK TO GAME ANSWER

31. © 2013 Pearson Education, Inc. Topic 3: Viral Pathogens $500 Answer Why is it difficult for antibodies to destroy HIV? a.HIV undergoes antigenic variation when an antibody binds to the virion. b. HIV infects and destroys the immune cells that produce and synthesize antibodies. c. They cannot reach the binding site for CD4 on the surface of the virus. d. Antibodies that target HIV are not produced by the host. BACK TO GAME

32. © 2013 Pearson Education, Inc. Topic 4: Eukaryotic Organisms $100 Question Which of the following does NOT contribute to fungal disease? a.cell walls b.toxins c.capsules d.allergic response of the host BACK TO GAME ANSWER

33. © 2013 Pearson Education, Inc. Topic 4: Eukaryotic Organisms $100 Answer Which of the following does NOT contribute to fungal disease? a.cell walls b.toxins c.capsules d.allergic response of the host BACK TO GAME

34. © 2013 Pearson Education, Inc. Topic 4: Eukaryotic Organisms $200 Question What type of organism produces saxitoxin? a. helminth b. alga c. fungus d. protozoan ANSWER BACK TO GAME

35. © 2013 Pearson Education, Inc. Topic 4: Eukaryotic Organisms $200 Answer What type of organism produces saxitoxin? a. helminth b. alga c. fungus d. protozoan BACK TO GAME

36. © 2013 Pearson Education, Inc. Topic 4: Eukaryotic Organisms $300 Question Which of the following toxins is an alkaloid that can cause hallucinations resembling those produced by LSD? a. aflatoxin b. ergot c. phalloidin d. amanitin BACK TO GAME ANSWER

37. © 2013 Pearson Education, Inc. Topic 4: Eukaryotic Organisms $300 Answer Which of the following toxins is an alkaloid that can cause hallucinations resembling those produced by LSD? a. aflatoxin b. ergot c. phalloidin d. amanitin BACK TO GAME

38. © 2013 Pearson Education, Inc. Topic 4: Eukaryotic Organisms $400 Question Which of the following eukaryotic organisms can attach to a host by a sucking disc? a. Candida albicans b. Entamoeba histolytica c. Giardia lamblia d. Plasmodium malariae BACK TO GAME ANSWER

39. © 2013 Pearson Education, Inc. Topic 4: Eukaryotic Organisms $400 Answer BACK TO GAME Which of the following eukaryotic organisms can attach to a host by a sucking disc? a. Candida albicans b. Entamoeba histolytica c. Giardia lamblia d. Plasmodium malariae

40. © 2013 Pearson Education, Inc. Topic 4: Eukaryotic Organisms $500 Question What is the causative agent of elephantiasis? a. Entamoeba histolytica b. Candida albicans c. Cryptococcus neoformans d. Wuchereria bancrofti BACK TO GAME ANSWER

41. © 2013 Pearson Education, Inc. Topic 4: Eukaryotic Organisms $500 Answer What is the causative agent of elephantiasis? a. Entamoeba histolytica b. Candida albicans c. Cryptococcus neoformans d. Wuchereria bancrofti BACK TO GAME

42. © 2013 Pearson Education, Inc. Topic 5: Portal of Exit $100 Question Arthropods provide a portal of exit for microbes in a.skin. b.blood. c.respiratory tract. d.genitourinary tract. BACK TO GAME ANSWER

43. © 2013 Pearson Education, Inc. Topic 5: Portal of Exit $100 Answer Arthropods provide a portal of exit for microbes in a.skin. b.blood. c.respiratory tract. d.genitourinary tract. BACK TO GAME

44. © 2013 Pearson Education, Inc. Topic 5: Portal of Exit $200 Question Sneezing is a portal of exit for the a.gastrointestinal tract. b.respiratory tract. c.blood. d.genitourinary tract. BACK TO GAME ANSWER

45. © 2013 Pearson Education, Inc. Topic 5: Portal of Exit $200 Answer Sneezing is a portal of exit for the a.gastrointestinal tract. b.respiratory tract. c.blood. d.genitourinary tract. BACK TO GAME

46. © 2013 Pearson Education, Inc. Topic 5: Portal of Exit $300 Question Pathogens that are discharged from the respiratory tract cause what disease? a.salmonella b.whooping cough c.poliomyelitis d.rabies BACK TO GAME ANSWER

47. © 2013 Pearson Education, Inc. Topic 5: Portal of Exit $300 Answer BACK TO GAME Pathogens that are discharged from the respiratory tract cause what disease? a.salmonella b.whooping cough c.poliomyelitis d.rabies

48. © 2013 Pearson Education, Inc. Topic 5: Portal of Exit $400 Question Infections transmitted from the skin include a.yaws. b.tularemia. c.yellow fever. d.plague. BACK TO GAME ANSWER

49. © 2013 Pearson Education, Inc. Topic 5: Portal of Exit $400 Answer Infections transmitted from the skin include a.yaws. b.tularemia. c.yellow fever. d.plague. BACK TO GAME

50. © 2013 Pearson Education, Inc. Topic 5: Portal of Exit $500 Question Which of the following diseases can be transmitted by a biting insect? a.shigellosis b.mumps c.tularemia d.chickenpox BACK TO GAME ANSWER

51. © 2013 Pearson Education, Inc. Topic 5: Portal of Exit $500 Answer Which of the following diseases can be transmitted by a biting insect? a.shigellosis b.mumps c.tularemia d.chickenpox BACK TO GAME

52. © 2013 Pearson Education, Inc. FINAL ROUND Question Septic shock can result from using antibiotics to treat a. gram-negative bacterial infections. b. fungal infections. c. viral infections. d. protozoan infections. BACK TO GAME ANSWER

53. © 2013 Pearson Education, Inc. FINAL ROUND Answer Septic shock can result from using antibiotics to treat a. gram-negative bacterial infections. b. fungal infections. c. viral infections. d. protozoan infections.. BACK TO GAME